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Examines the role of the ANS in the maintenance and control of bodily homeostasis, as well as in the pathogenesis, pathophysiology, and treatment of disorders such as cardiovascular disease, hypertension, asthma, arrhythmia, diabetes, ischemia, myocardial infarction, urinary retention, and depression.
This comprehensive reference describes the clinical manifestations and underlying physiological and pathophysiological mechanisms of human autonomic nervous system disorders-detailing the latest methods for testing autonomic nervous system functions.
Autonomic Nervous System provides an introduction to the latest science and detailed chapters on advances in the clinical diagnosis and treatment of autonomic system disorders. The autonomic nervous system controls all involuntary actions within the human nervous system. Core body functions regulated by the autonomic system include breathing, heartbeat, blood pressure, body temperature, perspiration, and bowel, bladder and sexual function. Our understanding of the neurotransmitters associated with the autonomic nervous system has expanded over the past 15 years associated with current research efforts and are now impacting the diagnosis and treatment of autonomic nervous system disorders by clinical neurologists. This volume is a valuable companion for neuroscience and clinical neurology researchers and practitioners. - A volume in the Handbook of Clinical Neurology series, which has an unparalleled reputation as the world's most comprehensive source of information in neurology - International list of contributors, including the leading workers in the field - Describes the advances that have occurred in clinical neurology and the neurosciences and their impact on the understanding of neurological disorders and on patient care
In 1964, George Solomon coined the term psychoneuroimmunology. In the intervening 30 years, this term has emerged into a dynamic field of study which investigates the unique interactions between the nervous, endocrine, and immune systems. The Handbook of Human Stress and Immunity is a comprehensive reference for this dynamic new field. Focusing on how stressors impact the central nervous system and the resulting changes in immune responses, the Handbook is the first to describehow stress specifically affects human immune systems. It discusses how stress generally makes people more susceptible to infection, how personal support systems can counteract the physiological effects of stress, and how stress, or lack of stress, affects the aging process. Chapters are authored by the leading names in the field and cover such diseases as autoimmune disease, viral pathogenesis, herpes, HIV, and AIDS.
This book is a guide to the everyday clinical management of disorders of the autonomic nervous system, from identification of the key symptoms of autonomic involvement and comprehensive history taking to choice of treatment. The book will assist the reader in determining the anatomic distribution of the disease, as well as underlying autonomic syndromes, and in transforming the clinical picture into a coherent explanation of the patient’s autonomic problem. In addition, guidelines are provided on selection of the most appropriate autonomic and laboratory tests and formulation of appropriate non-pharmacological and pharmacological management strategies. With cases drawn from clinical experience and a list of available online resources, Bedside Approach to Autonomic Disorders will aid the reader in acquiring the skills that are mandatory in order to put patients on the right clinical track. It will be a valuable guide for trainees and young doctors interested in autonomic disorders from the fields of neurology, internal medicine, cardiology, diabetology, and urology.
Handbook of Innovations in CNS Regenerative Medicine provides a comprehensive overview of the CNS regenerative medicine field. The book describes the basic biology and anatomy of the CNS and how injury and disease affect its balance and the limitations of the present therapies used in the clinics. It also introduces recent trends in different fields of CNS regenerative medicine, including cell transplantation, bio and neuro-engineering, molecular/pharmacotherapy therapies and enabling technologies. Finally, the book presents successful cases of translation of basic research to first-in-human trials and the steps needed to follow this path. Areas such as cell transplantation approaches, bio and neuro-engineering, molecular/pharmacotherapy therapies and enabling technologies are key in regenerative medicine are covered in the book, along with regulatory and ethical issues. - Describes the basic biology and anatomy of the CNS and how injury and disease affect its balance - Discusses the limitations of present therapies used in the clinics - Introduces the recent trends in different fields of CNS regenerative medicine, including cell transplantation, bio and neuro-engineering, molecular/pharmacotherapy therapies, and enabling technologies - Presents successful cases of translation of basic research to first-in-human trials, along with the steps needed to follow this path
"The Dysautonomia Project" is a much needed tool for physicians, patients, or caregivers looking to arm themselves with the power of knowledge. It combines current publications from leaders in the field of autonomic disorders with explanations for doctors and patients about the signs and symptoms, which will aid in reducing the six-year lead time to diagnosis.
This volume provides a comprehensive accounting of pain and its relation to neurology. It is dedicated entirely to the mechanisms and clinical aspects of the subject, and provides a wealth of information on the latest neurobiological and clinical data surrounding the topic. From discussions of the physiology and pathology of the pain pathways from signaling, via spinal cord and supraspinal processing to endogenous pain modulation, users will gain an invaluable reference that provides a new understanding of pain related topics, including cytokines, sex differences, and the autonomic nervous system. Practicing clinicians, internists, surgeons, and those in the fields of psychiatry and gerontology will gain a greater understanding of this challenging topic with chapters that deal extensively with peripheral and central pain conditions, including specific disorders such as fibromyalgia, whiplash, psychiatric diseases, dementia, and even cancer. In addition, treatments for neuropathic pain are also thoroughly presented and discussed. * A comprehensive guide to the topic of pain and its relation to neurology* Invaluable information on specific topics of interest, including discussions of pain and its implications for related diseases and conditions such as fibromyalgia, whiplash, and even psychiatric disorders* Treatment protocols for neuropathic pain and patient care
Thoroughly updated for its Third Edition, this text will be the definitive reference on autonomic nervous system disorders, for practicing and academic neurologists and clinicians in such areas as cardiology and gastroenterology where autonomic disorders are prevalent. The book focuses on patient care and provides the sophisticated laboratory testing information necessary for clinical diagnosis and management.This edition has a new co-editor, Eduardo E. Benarroch, MD, who provides more detailed information on the role of the central nervous system in autonomic disorders. The book incorporates the latest advances in noninvasive laboratory testing to evaluate abnormalities in the control of blood pressure, heart rate, urination, digestion, sexual function, and sweating.
Straightforward and practical, this is the first book to provide detailed guidance for using neurobiological methods in the study of human social behavior, personality, and affect. Each chapter clearly introduces the method at hand, provides examples of the method's applications, discusses its strengths and limitations, and reviews concrete experimental design considerations. Written by acknowledged experts, chapters cover neuroimaging techniques, genetic measurement, hormonal methods, lesion studies, startle eyeblink responses, facial electromyography, autonomic nervous system responses, and modeling based on neural networks.