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This multivolume reference work addresses the fact that the well being of humankind is predicated not only on individuals receiving adequate nutrition but also on their genetic makeup. The work includes more than 100 chapters organized in the following major sections: Introduction and Overview; Epigenetics of Organs and Diseases in Relation to Diet and Nutrition; Detailed Processes in Epigenetics of Diet and Nutrition; Modulating Epigenetics with Diet and Nutrition; and Practical Techniques. While it is well known that genes may encode proteins responsible for structural and dynamic components, there is an increasing body of evidence to suggest that nutrition itself may alter the way in which genes are expressed via the process of epigenetics. This is where chemically imposed alteration in the DNA sequence occurs or where the functional expression of DNA is modulated. This may include changes in DNA methylation, non-coding RNA, chromatin, histone acetylation or methylation, and genomic imprinting. Knowledge regarding the number of dietary components that impact on epigenetic processes is increasing almost daily. Marshalling all the information on the complex relationships between diet, nutrition, and epigenetic processes is somewhat difficult due to the wide myriad of material. It is for this reason that the present work has been compiled.
Handbook of Epigenetics: The New Molecular and Medical Genetics, Second Edition, provides a comprehensive analysis of epigenetics, from basic biology, to clinical application. Epigenetics is considered by many to be the new genetics in that many biological phenomena are controlled, not through gene mutations, but rather through reversible and heritable epigenetic processes. These epigenetic processes range from DNA methylation to prions. The biological processes impacted by epigenetics are vast and encompass effects in lower organisms and humans that include tissue and organ regeneration, X-chromosome inactivation, stem cell differentiation, genomic imprinting, and aging. The first edition of this important work received excellent reviews; the second edition continues its comprehensive coverage adding more current research and new topics based on customer and reader reviews, including new discoveries, approved therapeutics, and clinical trials. From molecular mechanisms and epigenetic technology, to discoveries in human disease and clinical epigenetics, the nature and applications of the science is presented for those with interests ranging from the fundamental basis of epigenetics, to therapeutic interventions for epigenetic-based disorders. Timely and comprehensive collection of fully up-to-date reviews on epigenetics that are organized into one volume and written by leading figures in the field Covers the latest advances in many different areas of epigenetics, ranging from basic aspects, to technologies, to clinical medicine Written at a verbal and technical level that can be understood by scientists and college students Updated to include new epigenetic discoveries, newly approved therapeutics, and clinical trials
"Food For Thought: An Epigenetic Guide to Wellness" By George J. Febish and Jo Anne Oxley You Make Your Own Luck! How to Change Your Health Luck! We have more Control Than we Think! American health is getting worse and people actually believe that getting old equates to getting ill. Co-authors George J. Febish and Jo Anne Oxley declare that this is absolutely not true. People are empowered to be as healthy as they can be. People do not have good or bad genes. The problem is that genes are being turned ON or OFF, which causes health or illness. In Food For Thought: An Epigenetic Guide to Wellness, the authors reveal what turns genes on and off and how people can control these switches. In this book, readers can explore two new fields of biology that impact the quality of life. Epigenetics is the study of how human genes are switched on and off. For example, cancer genes can either be turned on or off and tumor fighting genes can be turned on or off. Nutrigenomics is the study of how different foods cause epigenetic switches to our genes. It is a mapping of which foods switch on or off which genes. The state of ones health is not random nor is it luck. It is the sum of all the decision a person makes in his of her life. It includes foods eaten and those not eaten, how one thinks, what one believes in as well as the physical environment one lives in. Food For Thought: An Epigenetic Guide to Wellness will teach readers how they can control life changing switches to improve their health, lifestyle, and mental attitude. Each one is responsible for his or her health. Doctors and the government are not responsible. Making the right decisions and living a better life is everybodys choice.
Nutrition and Epigenetics presents new information on the action of diet and nutritional determinants in regulating the epigenetic control of gene expression in health and disease. Each chapter gives a unique perspective on a different nutritional or dietary component or group of components, and reveals novel mechanisms by which dietary factors modulate the epigenome and affect development processes, chronic disease, and the aging process. This pivotal text: Documents the epigenetic effect of antioxidants and their health benefits Adds to the understanding of mechanisms leading to disease susceptibility and healthy aging Illustrates that the epigenetic origins of disease occur in early (fetal) development Synthesizes the data regarding nutrient and epigenomic interactions Nutrition and Epigenetics highlights the interactions among nutrients, epigenetics, and health, providing an essential resource for scientists and clinical researchers interested in nutrition, aging, and metabolic diseases.
The new edition of the Handbook of Nutrition and Food follows the format of the bestselling earlier editions, providing a reference guide for many of the issues on health and well being that are affected by nutrition. Completely revised, the third edition contains 20 new chapters, 50 percent new figures, and updates to most of the previously existi
​This easy to use text provides practitioners and researchers with a global view of current and emerging issues concerned with successful pregnancy outcomes and approaches that have been successful or show promise in ensuring a successful pregnancy. The fully updated and revised second edition expands its scope with topics not covered in the first edition including pregnancy and military service; sleep disorders during pregnancy; the gut microbiome during pregnancy and the newborn; requirement for vitamin D in pregnancy; the environment—contaminants and pregnancy; preeclampsia and new approaches to treatment; health disparities for whites, blacks, and teen pregnancies; depression in pregnancy—role of yoga; safe food handling for successful pregnancy outcome; relationship of epigenetics and diet in pregnancy; caffeine during pregnancy; polycystic ovary syndrome; US Hispanics and preterm births; celiac disease and pregnancy; cannabis use during pregnancy. The second edition of Handbook of Nutrition and Pregnancy will be a valuable resource for clinicians and other healthcare professionals who treat and counsel women of child-bearing age and pregnant women.
This book disseminates current information pertaining to the modulatory effects of foods and other food substances on behavior and neurological pathways and, importantly, vice versa. This ranges from the neuroendocrine control of eating to the effects of life-threatening disease on eating behavior. The importance of this contribution to the scientific literature lies in the fact that food and eating are an essential component of cultural heritage but the effects of perturbations in the food/cognitive axis can be profound. The complex interrelationship between neuropsychological processing, diet, and behavioral outcome is explored within the context of the most contemporary psychobiological research in the area. This comprehensive psychobiology- and pathology-themed text examines the broad spectrum of diet, behavioral, and neuropsychological interactions from normative function to occurrences of severe and enduring psychopathological processes.
Explores the Newly Discovered Link Between Nutrition and EpigeneticsCurrent research suggests that nutrients are more than just food components and that certain nutrients can impact the expression of genes that lead to the development of chronic diseases. With contributions from experts in both fields, Nutrients and Epigenetics examines the epigene
Epigenetics is emerging as an important factor in risk of diseases of global importance including obesity, cardiovascular disease and cancer. Unlike gene polymorphisms which have been the focus of understanding the role of inherited disease susceptibility for some time, epigenetic can be modified by environmental factors, in particular nutrition. Thus research into the role of epigenetics in disease has substantial potential for explaining the impact of the environmental factors such as diet on disease risk. Since epigenetic processes can be modified by nutrition, it may be possible to modify inappropriate epigenetic marks by nutritional interventions to reduce disease risk. This book will explore current understanding of the interaction between nutrition, epigenetics and disease risk, will place this knowledge in the context of global health and discuss the ethical implications of this research.