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Oncology has developed as a subspecialty of medicine with unique and often complex clinical problems. This handbook ofhematologic and oncologic emer gencies provides a compact, concise, yet comprehensive guide to the manage ment of a variety of difficult clinical situations. The authors of the various chapters are all clinicians with experience in the management of these difficult patients. Their efforts provide insight and a ready source of practical infor mation which lends itself to use in the clinic and in the inpatient ward. The authors sincerely hope that this handbook will be of service to house officers and fellows alike, as they develop skills in the management of the emergent problems of patients with hematologic and other neoplasms. Janice P. Dutcher Peter H. Wiernik Bronx, New York, ;; Contents 1. Syndrome of Inappropriate Antidiuretic Hormone Secretion and Hyponatremia ... 000 ... Stuart L. Marcus, M.D., Ph. D., and Joachim Z. Fuks, M.D. 1. Introduction ... 1 2. Mechanisms ... 3 3. Etiology ... . 3 4. Diagnosis ... 5 5. Treatment ... . 6 References ... . 8 2. Acute Tumor Lysis Syndrome: Prevention and Management . . 9 Stuart L. Marcus, M.D., Ph. D., and Avi I. Einz;ig, M.D. 1. Introduction ... 9 2. Risk Factors for the Development of Azotemia in Acute Tumor Lysis Syndrome ... 10 3. Metabolic Abnormalities That Occur during Acute Tumor Lysis Syndrome ... 11 ... 4. Prevention of Acute Tumor Lysis Syndrome: Management prior to Beginning Chemotherapy ... 13 ... 5. Posttreatment Management: Indications for Dialysis ... 14 . . References ... 15 ...
This issue of Emergency Medicine Clinics focuses on Hematology and Oncology Emergencies, with topics including: Cardiovascular toxicities of cancer therapies; The latest cancer agents and their complications; Infections in the cancer patient; Pediatric oncologic emergencies; Rapid fire oncologic emergencies; Rapid fire hypercalcemia; Rapid fire sickle cell disease; Rapid fire SVC Syndrome; The Cancer ED; EM Oncology Fellowship; Anticoagulation Reversal; and Rapid Fire Blast Crisis/Hyperviscosity.
This issue of Emergency Medicine Clinics edited by Drs. John Perkins and and Jonathan Davis focuses on emergencies related to Hematology/Oncology and covers topics such as: Oncologic Mechanical Emergencies, Neutropenic Fever, Oncologic Metabolic Emergencies, Acute Leukemias, Pediatric Oncologic Emergencies, Chemotherapeutic Medications and their Emergent Complications, Anemia, Thrombotic Microangiopathies (TTP, HUS, HELLP), Congenital Bleeding Disorders, Acquired Bleeding Disorders and Antithrombotic agents, Sickle Cell Disease, and more!
Handbook of Hematologic Malignancies provides a unique, practical, and concise guide focused on the must-know points of diagnosis, prognosis, therapeutic management, and cutting edge clinical trial opportunities for each hematologic malignancy. With an ever-increasing growth of evidence and a significant expansion of available treatment options for patients with hematologic disease, remaining current and up-to-date can be extremely challenging for practicing clinicians. This comprehensive subspecialty handbook is designed and organized for the busy hematologist, hematologic oncologist, hematopathologist, and trainee in mind. Every chapter is richly illustrated with color figures and flow diagrams, and contains helpful tables on differential diagnosis, prognostic scoring systems and therapeutic options. A concise case-based review for testing pathologic diagnosis and clinical knowledge for each chapter is included for digital download online and in the e-book. Written by experienced clinicians at the world-renowned Moffitt Cancer Center in Tampa, Florida, as well as contributions from leading academicians throughout the country, this handbook is an essential resource for anyone diagnosing, treating, or managing patients with hematologic malignancy. KEY FEATURES: Contains clear prognostic and diagnostic tools (e.g., tables/flow diagrams/pathology images) with emphasis on key differential diagnoses and diagnostic dilemmas Easy to use treatment recommendations with bullet point format and key references. Discusses the future of patient management based on practice changing clinical trials Includes access to digitally downloadable case-based clinical scenarios and questions with high resolution pathology images linked to each individual chapter
This new resource on managing oncologic emergencies is directed at all health care professionals who care for patients with cancer or survivors. Edited and written by clinician-experts at The University of Texas MD Anderson Cancer Center, the book covers the full range of oncologic emergencies, from cardiac and neurologic to orthopedic to hematologic, and addresses important palliative care, ethical, and Emergency Department considerations. Chapters are structured with busy clinicians in emergent and urgent settings in mind, and each chapter concludes with a series of key practice points and a list of suggested readings for those who wish to delve deeper into a subject. For any clinician facing the increasing number of patients who experience an oncologic emergency, this is an up-to-date, clinically focused, and authoritative resource.
This revised and updated second edition of Handbook of Hematologic Malignancies continues to be an essential and "go-to" resource for the busy hematologist, hematologic oncologist, hematopathologist, oncology advanced practice provider, oncology nurse, and trainee. Concisely organized, each chapter provides the most current, need-to-know points of diagnosis, prognosis, therapeutic management, and clinical trial opportunities for each hematological malignancy. Chapters are complete with richly illustrated figures to highlight the hematopathologic characteristics of diseases in addition to helpful tables on differential diagnosis, prognostic scoring systems, molecular profiles, and therapeutic options. A new case-based chapter concludes the handbook with clinical cases designed to test a clinician's knowledge of pathologic diagnosis and clinical presentation of diseases covered in the book. With over twenty new FDA-approved indications since publication of the first edition, including breakthroughs with CAR-T therapy, and other evidence-based treatment options for patients with hematologic disease, this book serves as quick reference to practice changing information on challenging diagnostic dilemmas, frontline and refractory treatment scenarios, and more. The subspecialty field of hematologic oncology is ever-changing and expanding with available treatment options and this second edition keeps the busy clinician abreast of recent findings and their impact on evidence-based treatment and management. Written by experienced clinicians at the world-renowned Moffitt Cancer Center in Tampa, Florida, as well as contributions from leading academicians, hematologists, and oncologists throughout the country, this unique handbook is packed with authoritative knowledge and clinical insight into all known hematologic cancers. Key Features: Includes seven new chapters covering CAR-T and novel therapeutic options including CD19 CAR-T therapy, novel cellular therapies, cytokine release syndrome, cancer associated thrombosis, and more Comprises compact and updated disease-site chapters describing new standards of care and management considerations in bullet point format with key references Highlights important diagnostic tools that assist with conducting key differential diagnoses and unveiling answers to diagnostic dilemmas Provides updates of potential practice-changing clinical trials and paradigm shifting treatment considerations in each disease-based chapter
Der überarbeitete Leitfaden für Diagnose, Management und Behandlung von Blutkrankheiten und Krebs bei Kindern. Kinder mit Blutkrankheiten und Krebs sind eine ganz spezifische Gruppe, die besondere Diagnosemaßnahmen und ein spezifisches Management erfordert. Das Handbook of Pediatric Hematology and Oncology stellt Klinikern auf jedem Niveau anhand eines aktuellen Algorithmus praxisorientierte Handlungsanleitungen zur Verfügung. Die aktualisierte dritte Auflage wurde von einem Expertenteam des Children`s Hospital & Research Center Oakland zusammengestellt. - Präsentiert aktuelle Management- und Behandlungsrichtlinien für die meisten bekannten Blutkrankheiten und bösartigen Krebserkrankungen. - Neuester Algorithmus-Ansatz für Diagnose und Management der häufigsten Krankheitsbilder mit Verweisen zur Fachliteratur. - Bietet zum schnellen Nachschlagen Tabellen mit visualisierten Darstellungen der Symptome, Laborergebnissen, Differenzialdiagnosen und beinhaltet Behandlungsempfehlungen. - Zeigt mittels Fallstudien die verschiedenen hämatologischen und onkologischen Aspekte, u. a. hämolytische Anämie, Sichelzellenkrankheit, Hämophilie, Neuroblastom, weiches und hartes Sarkom. -Enthält eine nützliche Arzneimittelliste und Informationen zu chemotherapeutischen Wirkstoffen, Dosierung, Handlungsmechanismen, Schwangerschaft, Indikationen und Nebenwirkungen. - Behandelt Transfusionsmedizin, Stammzellentransplantation, Management zentraler Venenkatheter, Schmerzbehandlung, onkologische Notfälle und Grundlagen der Chemotherapie. Aufgrund seiner Praxisorientierung und des handlichen Formats ist die 3. Auflage des Handbook of Pediatric Hematology and Oncology eine unschätzbare Quelle für Medizinstudenten, Praktikanten, Patienten, Fach- und Pflegepersonal in der pädiatrischen Hämatologie und Onkologie, Kinderärzte und Einsteiger in das Fachgebiet der Hämatologie und Onkologie.
The Handbook of Cancer Emergencies is a portable, up-to-date, comprehensive guide to the most common oncologic emergencies, acute medical disorders, and treatment-related complications that can occur with malignancy. Topics covered include cardiac tamponade, spinal cord compression, hypercalcemia, and all other major emergent disorders seen in the cancer patient. This easy-to-use, affordable, quick reference is an essential resource not only for oncologists/hematologists, but also for physicians and healthcare professionals of varying specialties who provide day-to-day patient care.