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Spasmodic torticollis, also known as cervical dystonia, affects about three people in 10,000, or an estimated 85,000 individuals in the United States alone. Despite this, there has been until now a lack of information outside of the professional medical literature for use by individuals with this disorder and their families. This book provides comprehensive information on the disorder for people with spasmodic torticollis and those close to them. Medical terms and concepts are introduced sequentially and then used as building blocks for the later discussion. Beginning with a clear definition of the disorder, opening chapters categorize this neurologic disease as one of the broader category of movement disorders, and differentiate it from other conditions with which it is often confused. The authors then present a stepwise introduction to the relevant anatomy and physiology of the nervous system and neck. They draw on the experiences of their patients to build a progressive depiction of the experiences an individual might have as he or she goes through the initial onset of symptoms, progression of the disorder, seeking medical care, diagnosis, treatment, and subsequent outcome. Personal vignettes from the experiences of selected patients are provided where they illustrate particular points in the discussion. Subsequent chapters discuss various modes of treatment for spasmodic torticollis. Prior to the mid-1980?s, there were no specific treatments for this disorder. Nearly all treatment consisted of using oral medications that were primarily intended for other medical conditions. Since most of these medications are still in use, and a few new ones have been added, a chapter is devoted to detailing them and discussing the general principles of medication therapy. During the past decade, chemodenervation using botulinum toxin has become the primary and most effective treatment for spasmodic torticollis. For those few patients who require surgery, a description is provided of the neurosurgical techniques developed during the last twenty years specifically for its treatment. The final chapter is a manual of therapeutic rehabilitation exercises designed to alleviate the symptoms of spasmodic torticollis. These exercises can be performed by most patients with no assistance and a bare minimum of equipment. Since each person?s case of spasmodic torticollis is different, only certain of the exercises may be appropriate for any given individual. They should be undertaken only after discussion with your physician. These exercises are accompanied by detailed illustrations that emphasize the particular muscles relevant to each posture or movement. About the Authors: Dr. Pathak is a neurologist with a special interest in the neurologic rehabilitation of movement disorders, especially spasmodic torticollis. Dr. Frei is a neurologist specialized in the field of neurogenetics, and has conducted clinical trials on a number of movement disorders, including spasmodic torticollis. Dr. Truong is a neurologist and movement disorders specialist. He has conducted active research in the management of movement disorders, including spasmodic torticollus. He was one of the pioneers in the use of botulinum toxin to manage this condition, and has lectured worldwide on the management of movement disorders.
As many as 250,000 people in the United States have dystonia, making it the third most common movement disorder following essential tremor and Parkinson's disease. Authoritative and reader-friendly, Handbook of Dystonia, Second Edition provides a wide-ranging overview of the latest research and developments regarding the pathogenesis, evaluation, and management of the disease. The book offers detailed coverage of every available treatment option for dystonia and includes four categorized sections on medical management, botulinum toxin injections, phenol and neurolytic therapy, and surgical intervention. The book reviews the genetic factors of dystonia and supplies in-depth coverage of the neuroanatomy, neurophysiology, and neuropathology of the disease. It covers secondary causes of dystonia, including drug-induced and psychogenic presentations. It also examines non-motor symptoms relating to movement disorders and analyzes innovative approaches for treatment including deep brain stimulation. New to the Second Edition: Four new chapters dedicated to the discussion of individual botulinum toxins recently approved to treat dystonia: Botox, Myobloc, Disport, and Xeomin Dystonic symptoms associated with Parkinson’s disorders The use of Transcranial Magnetic Stimulation (TMS) as a treatment option for dystonia Spasticity and its pathogenesis, evaluation, and treatment with toxins, other injectables and surgical therapies Summarizing what is known about the disorder, the book dramatically improves the recognition and understanding of this debilitating disease.
As many as 250,000 people in the United States have dystonia, making it the third most common movement disorder following essential tremor and Parkinson's disease.Authoritative and reader-friendly, Handbook of Dystonia, Second Edition provides a wide-ranging overview of the latest research and developments regarding the pathogenesis, evaluation, an
There is a dearth of books on neurological examination that give a comprehensive analysis of the subject. Dr. Navneet Kumar, with his expertise and vast teaching as well as practising experience, provides tips to the students and practitioners to conduct neurological examination of the patients in a scientific and systematic manner. He shows with, great skill, how the examination of first impression and gait, history taking, and examination of higher mental functions including speech are to be conducted. The book, in the Second Edition, has been updated and enhanced by introducing more illustrations and visuals for clear understanding and diagnosis of diseases and disorders. The text focuses on the examination of all the cranial nerves (First to Twelfth), the motor system, movement disorders, the sensory system, the autonomic nervous system, and bladder dysfunction, with equal deftness, besides other important concepts. This systematically organised book provides different approaches to examine the unconscious patient, and special neurological situations, the methods of neurological investigation, as well as the methods of case sheet writing. Primarily intended as a practical handbook for the students of MBBS, MD (Medicine), DNB (Medicine), Paediatrics and Psychiatry, the book would also be of great value to the students pursuing DM (Neurology) and M.Ch. (Neurosurgery) as well as practising physicians and neurologists. KEY FEATURES • Gives anatomical details of all cranial nerves. • Highlights common problems in neurology, generally not mentioned in any other handbook. • Provides about 200 real photographs and diagrams, and also a large number of tables to illustrate the concepts. • Includes a thorough analysis of neurological investigations. TARGET AUDIENCE • MBBS / MD (Medicine) / DNB (Medicine) • Paediatrics & Psychiatry • DM (Neurology) / M.Ch. (Neurosurgery)
Fully updated throughout, the second edition of the Manual of Botulinum Toxin Therapy provides practical guidance on the use of Botox in a wide variety of disorders. New chapters have been added on the use of botulinum toxin in wound healing, in focal hand dystonia and in thoracic outlet syndrome, as well as others. There are new chapters on the use of botulinum toxins in conjunction with ultrasound guidance. Using clear line-drawings the Manual describes the relevant injection sites for each condition and gives comparative dosage tables for the various formulations of toxins used in different muscle groups. Throughout the emphasis is on technique and the book can be used as both a teaching aid and in bedside guidance. The manual will be of use to neurologists, otolaryngologists, urologists, ophthalmologists, dermatologists, internists, pain management specialists, rehabilitation specialists and plastic surgeons, and any other clinicians discovering the potential of botulinum toxin.
Botulinum toxin A is a remarkably versatile treatment with a steadily expanding list of indications, which include strabismus, hemifacial spasm, focal dystonias such as spasmodic torticollis, dysphonia and writer’s cramp, as well as adult and childhood spasticity. Recent innovations include its use in some types of pain, in autonomic and gastrointestinal disorders, and in cosmetic medicine, such as hyperhidrosis, hypersalivation, rectal fissure, achalasia and facial wrinkles. Botulinum toxin is arguably the safest and most effective treatment in movement disorders since the introduction of levodopa, and is an increasingly important option in many other fields. The long-awaited second edition of the Handbook of Botulinum Toxin Treatment brings the reader up to date with the many advances in background knowledge and in clinical practice in both the established and the newer indications, including the use of a second serotype botulinum toxin B. The book is an introduction and practical guide for doctors and paramedical staff who use botulinum toxin or who may want to refer patients or care for patients being treated elsewhere. Initial chapters provide historical and general information. The rest of the book concentrates on the different conditions treated with botulinum toxin. Chapters follow a standard format with a pragmatic approach based on the wide experience of the authors.
"Rating scales are used daily by everyone involved in the management of patients with neurologic disease and in the design and management of neurologic clinical trials. Now there is a single source for the wide range of scales used in specific neurologic diseases and neurorehabilitation. You will refer to this volume constantly! The first edition of the Handbook of Neurologic Rating Scales quickly became an invaluable reference work on the increasing array of scales for measuring neurologic disease. In the brief few years since the first edition the importance of this book has only increased. New Chapters Include Scales On: Generic and general use Pediatric neurology and rehabilitation Peripheral neuropathy and pain Ataxia HIV/AIDS And instruments for diagnosing headaches. Formal measurement of the effects of neurologic disease and of treatment effects, beyond the description of changes on the standard neurologic examination, is a relatively recent development. Controlled clinical trials and outcomes research are at the heart of modern information-based medicine, and neurologic scales are essential tools in clinical trials designed to provide this information. A Resource for Clinical Trials The Handbook of Neurologic Rating Scales provides a resource for clinicians and clinical investigators in the broad field of neurology and neurologic rehabilitation to help them: evaluate the clinical trials literature by providing information on the scales being used evaluate and select appropriate and efficient scales for clinical trials and outcomes research, and provide information that will help them to develop new scales or measures or to improve existing ones. A Resource for Evaluating Disease Status Outcomes research is playing an increasingly important role in clinical management and neurorehabilitation, and these also depend largely on measurement of disease status and change. In this era of managed care, neurologists must produce outcomes data demonstrating the effectiveness of neurologic care if the specialty is to survive, and certainly if it is to thrive. Even effective therapies are likely to fall by the wayside if studies to prove their effectiveness are not done. Comprehensive and Standardized Information on All Scales Each chapter in this volume contains the scales of importance and in current use, including a sequence of scale descriptions and specific scales in a standard format, as well as a summary and recommendations indicating which scales are most useful for specific purposes and whether a combination of scales is particularly useful or if better scales are needed. Each entry notes: the purpose for which the scale was developed and its current uses if they differ from those for which it was developed a detailed description of the scale information about validation, such as: Does the scale have face validity? i.e., does it appear to measure what it purports to measure? how and by whom the scale is administered the time needed to administer and score the scale the scale itself or, when the scale is proprietary or too long for inclusion, a description and key references special considerations, including unusual measures needed to obtain a valid score or problems in administering the test in specific patients advantages, or what makes the scale good or useful. Disadvantages, or what makes the scale difficult to use or impairs its reliability key references, including the original publication of the scale and its validation Downloadable PDFs of the scales contained in the Handbook of Neurologic Rating Scales are included with the purchase of this book. The password to download the files can be found in the book itself.
Principles and Practice of Movement Disorders provides the complete, expert guidance you need to diagnose and manage these challenging conditions. Drs. Stanley Fahn, Joseph Jankovic and Mark Hallett explore all facets of these disorders, including the latest rating scales for clinical research, neurochemistry, clinical pharmacology, genetics, clinical trials, and experimental therapeutics. This edition features many new full-color images, additional coverage of pediatric disorders, updated Parkinson information, and many other valuable updates. An accompanying Expert Consult website makes the content fully searchable and contains several hundred video clips that illustrate the manifestations of all the movement disorders in the book along with their differential diagnoses. Get just the information you need for a clinical approach to diagnosis and management, with minimal emphasis on basic science. Find the answers you need quickly and easily thanks to a reader-friendly full-color format, with plentiful diagrams, photographs, and tables. Apply the latest advances to diagnosis and treatment of pediatric movement disorders, Parkinson disease, and much more. View the characteristic presentation of each disorder with a complete collection of professional-quality, narrated videos online. Better visualize every concept with new full-color illustrations throughout. Search the complete text online, follow links to PubMed abstracts, and download all of the illustrations, at www.expertconsult.com.
Movement Disorders in Childhood, Second Edition, provides the most up-to-date information on the diseases and disorders that affect motor control, an important area of specialization within child neurology. Over the past several decades, advances in genetics, neuroimaging, neurophysiology, and other areas of neuroscience have provided new understanding of the underlying etiologies and mechanisms of these conditions as well as new opportunities for more accurate diagnosis and effective treatment. This new edition builds upon the success of the first edition, with comprehensive scientific and clinical updates of all chapters. In addition, there are new chapters on hereditary spastic paraplegia, quantitative motor assessments, autoimmune disorders, and movement disorders in the developmental neuropsychiatric disorders ADHD, OCD, and autism. Additional materials are provided on the latest in drug treatments, computer based strategies for genetic diagnosis, and helpful videos for phenomenology. - Provides the only current reference specifically focused on childhood movement disorders - Investigates the underlying etiologies and mechanisms of these disorders - Completely revised and updated with new materials and a more disease-oriented approach - New coverage of genetics and movement disorders, immunology and movement disorders, and an introduction to the latest quantitative analysis - New videos of instructive and unusual childhood movement disorders - 2016 BMA Medical Book Awards Highly Commended in Neurology
Connectomic Deep Brain Stimulation (DBS) covers this highly efficacious treatment option for movement disorders such as Parkinson's Disease, Essential Tremor and Dystonia. The book examines its impact on distributed brain networks that span across the human brain in parallel with modern-day neuroimaging concepts and the connectomics of the brain. It asks several questions, including which cortical areas should DBS electrodes be connected in order to generate the highest possible clinical improvement? Which connections should be avoided? Could these connectomic insights be used to better understand the mechanism of action of DBS? How can they be transferred to individual patients, and more. This book is suitable for neuroscientists, neurologists and functional surgeons studying DBS. It provides practical advice on processing strategies and theoretical background, highlighting and reviewing the current state-of-the-art in connectomic surgery. - Written to provide a "hands-on" approach for neuroscience graduate students, as well as medical personnel from the fields of neurology and neurosurgery - Includes preprocessing strategies (such as co-registration, normalization, lead localization, VTA estimation and fiber-tracking approaches) - Presents references (key articles, books and protocols) for additional detailed study - Provides data analysis boxes in each chapter to help with data interpretation