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Research on bacterial adhesion and its significance is a major field involving many different aspects of nature and human life, such as marine science, soil and plant ecology, most importantly, the biomedical field. The adhesion ofbacteria to the food industry, and human tissue surfaces and implanted biomaterial surfaces is an important step in the patho genesis of infection. Handbook 0/ Bacterial Adhesion: Principles, Methods, and Applications is an outgrowth of the editors' own quest for information on laboratory techniques for studying bacte rial adhesion to biomaterials, bone, and other tissues and, more importantly, a response to significant needs in the research community. This book is designed to be an experimental guide for biomedical scientists, biomaterials scientists, students, laboratory technicians, or anyone who plans to conduct bacterial adhesion studies. More specifically, it is intended for all those researchers facing the chal lenge of implant infections in such devices as orthopedic prostheses, cardiovascular devices or catheters, cerebrospinal fluid shunts or extradural catheters, thoracic or abdominal catheters, portosystemic shunts or bile stents, urological catheters or stents, plastic surgical implants, oral or maxillofacial implants, contraceptive implants, or even contact lenses. It also covers research methods for the study of bacterial adhesion to tis sues such as teeth, respiratory mucosa, intestinal mucosa, and the urinary tract. In short, it constitutes a handbook for biomechanical and bioengineering researchers and students at all levels.
Handbook of Antimicrobial Coatings is the first comprehensive work on the developments being made in the emerging field of antimicrobial coatings. Crucial aspects associated with coating research are presented in the form of individual chapters. Particular close attention has been given to essential aspects necessary to understand the properties of novel materials. The book introduces the reader to progress being made in the field, followed by an outline of applications in different areas. Various methods and techniques of synthesis and characterization are detailed as individual chapters. Chapters provide insight into the ongoing research, current trends and technical challenges in this rapidly progressing field. The covered topics were chosen so that they can be easily understood by new scholars as well as advanced learners. No book has been written on this topic thus far with so much crucial information for materials scientists, engineers and technologists. - Offers the first comprehensive work on developments being made in the emerging field of antimicrobial coatings - Features updates written by leading experts in the field of anti-microbial coatings - Includes discussions of coatings for novel materials - Provides various methods and techniques of synthesis and characterization detailed in individual chapters
Biofilms and Implantable Medical Devices: Infection and Control explores the increasing use of permanent and semi-permanent implants and indwelling medical devices. As an understanding of the growth and impact of biofilm formation on these medical devices and biomaterials is vital for protecting the health of the human host, this book provides readers with a comprehensive treatise on biofilms and their relationship with medical devices, also reporting on infections and associated strategies for prevention. - Provides useful information on the fundamentals of biofilm problems in medical devices - Discusses biofilm problems in a range of medical devices - Focuses on strategies for prevention of biofilm formation
This book explores the relationship between the surface roughness of artificial implants used for hard tissue replacement and their bacterial adhesion.
PEEK biomaterials are currently used in thousands of spinal fusion patients around the world every year. Durability, biocompatibility and excellent resistance to aggressive sterilization procedures make PEEK a polymer of choice, replacing metal in orthopedic implants, from spinal implants and hip replacements to finger joints and dental implants. This Handbook brings together experts in many different facets related to PEEK clinical performance as well as in the areas of materials science, tribology, and biology to provide a complete reference for specialists in the field of plastics, biomaterials, medical device design and surgical applications. Steven Kurtz, author of the well respected UHMWPE Biomaterials Handbook and Director of the Implant Research Center at Drexel University, has developed a one-stop reference covering the processing and blending of PEEK, its properties and biotribology, and the expanding range of medical implants using PEEK: spinal implants, hip and knee replacement, etc. Covering materials science, tribology and applications Provides a complete reference for specialists in the field of plastics, biomaterials, biomedical engineering and medical device design and surgical applications
Fimbriae are the best-studied bacterial colonization factors. They are of paramount importance in bacterial pathogenesis and microbial ecology. Due to the advent of new and powerful techniques, an impressive amount of information has been accumulated on these important surface organelles over the last decade. The first book of its kind, Fimbriae brings together into one volume the state of the art of this very active field. Internationally recognized researchers give both a horizontal and lateral approach to fimbriology. Selected types of fimbriae are extensively reviewed and fundamental questions such as evolution, control or regulation, biogenesis, bacteria-host interaction, and fimbriae-based vaccines are examined.
Study of the phenomena of bacterial adhesion to surfaces has accelerated considerably over the past 10 to 15 years. During this period, microbiologists have become increasingly aware that attachment to a substratum influences considerably the activities and structures of microbial cells. Moreover, in many cases attached communities of cells have important effects on their substratum and the surrounding environment. Such phenomena are now known to be important in plant and animal hosts, water and soil ecosystems, and man-made structures and industrial processes. Much work on microbial adhesion in the early 1970s was descriptive. Those studies were important for detecting and describing the phenomena of bacterial adhesion to substrata in various environments; the findings have been presented in numerous recently published, excellent books and reviews. In some studies, attempts were made to elucidate some funda mental principles controlling adhesion processes in different environments containing a variety of microorganisms. Common threads have been observed occasionally in different studies. Taken as a whole, however, the information has revealed that many disparate factors are involved in adhesion processes. Whether a particular microorganism can adhere to a certain substratum depends on the properties of the microbial strain itself and on charac teristics of the substratum and of the environment.
The Bad Bug Book 2nd Edition, released in 2012, provides current information about the major known agents that cause foodborne illness.Each chapter in this book is about a pathogen—a bacterium, virus, or parasite—or a natural toxin that can contaminate food and cause illness. The book contains scientific and technical information about the major pathogens that cause these kinds of illnesses.A separate “consumer box” in each chapter provides non-technical information, in everyday language. The boxes describe plainly what can make you sick and, more important, how to prevent it.The information provided in this handbook is abbreviated and general in nature, and is intended for practical use. It is not intended to be a comprehensive scientific or clinical reference.The Bad Bug Book is published by the Center for Food Safety and Applied Nutrition (CFSAN) of the Food and Drug Administration (FDA), U.S. Department of Health and Human Services.
The Perfect Slime presents the latest state of knowledge and all aspects of the Extracellular Polymeric Substances, (EPS) matrix – from the ecological and health to the antifouling perspectives. The book brings together all the current material in order to expand our understanding of the functions, properties and characteristics of the matrix as well as the possibilities to strengthen or weaken it. The EPS matrix represents the immediate environment in which biofilm organisms live. From their point of view, this matrix has paramount advantages. It allows them to stay together for extended periods and form synergistic microconsortia, it retains extracellular enzymes and turns the matrix into an external digestion system and it is a universal recycling yard, it protects them against desiccation, it allows for intense communication and represents a huge genetic archive. They can remodel their matrix, break free and eventually, they can use it as a nutrient source. The EPS matrix can be considered as one of the emergent properties of biofilms and are a major reason for the success of this form of life. Nevertheless, they have been termed the “black matter of biofilms” for good reasons. First of all: the isolation methods define the results. In most cases, only water soluble EPS components are investigated; insoluble ones such as cellulose or amyloids are much less included. In particular in environmental biofilms with many species, it is difficult to impossible isolate, separate the various EPS molecules they are encased in and to define which species produced which EPS. The regulation and the factors which trigger or inhibit EPS production are still very poorly understood. Furthermore: bacteria are not the only microorganisms to produce EPS. Archaea, Fungi and algae can also form EPS. This book investigates the questions, What is their composition, function, dynamics and regulation? What do they all have in common?