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With a new focus on evidence-based practice, the 3rd edition of this authoritative reference covers every aspect of infusion therapy and can be applied to any clinical setting. Completely updated content brings you the latest advances in equipment, technology, best practices, guidelines, and patient safety. Other key topics include quality management, ethical and legal issues, patient education, and financial considerations. Ideal as a practical clinical reference, this essential guide is also a perfect review tool for the CRNI examination. - Authored by the Infusion Nurses Society, this highly respected reference sets the standard for infusion nursing practice. - Coverage of all 9 core areas of INS certification makes this a valuable review resource for the examination. - Material progresses from basic to advanced to help new practitioners build a solid foundation of knowledge before moving on to more advanced topics. - Each chapter focuses on a single topic and can serve as a stand-alone reference for busy nursing professionals. - Expanded coverage of infusion therapy equipment, product selection, and evaluation help you provide safe, effective care. - A separate chapter on infusion therapy across the continuum offers valuable guidance for treating patients with infusion therapy needs in outpatient, long-term, and home-care, as well as hospice and ambulatory care centers. - Extensive information on specialties addresses key areas such as oncology, pain management, blood components, and parenteral nutrition. - An evidence-based approach and new Focus on Evidence boxes throughout the book emphasize the importance of research in achieving the best possible patient outcomes. - The user-friendly design highlights essential information in handy boxes, tables, and lists for quick access. - Completely updated coverage ensures you are using the most current infusion therapy guidelines available.
It is our wish that readers discover the importance of polymyxin structure in relation to the mechanisms of activity, resistance and toxicity. We emphasized that reliable analytic methods for polymyxins are critical when investigating their pharmacokinetics (PK) and pharmacodynamics (PD). The complicated dose definitions and different pharmacopoeial standards have already compromised the safe use of polymyxins in patients. Therefore, informed by the latest pharmacological information, scientifically-based dosing recommendations have been proposed for intravenous polymyxins. Considering the PK/PD limitations and potential development of resistance, polymyxin combinations are encouraged; however, the current literature has not shown definite microbiological benefits, possibly because most clinical studies to date overlooked key PK/PD principles. Nephrotoxicity is the major dose-limiting factor and it is imperative to elucidate the mechanisms and develop novel approaches to minimize polymyxin-associated toxicities. In addition, the anti-endotoxin effect of polymyxins supports their clinical use to treat Gram-negative sepsis. Fortunately, the discovery of new-generation polymyxins with wider therapeutic windows has benefited from the latest achievements in polymyxin research.
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A classic in its field, this popular text provides clinical coverage of critical care nursing, with an emphasis on holism in practice. Beginning with the psychosocial concepts of care, the text progresses through assessment and management of a variety of disorders. Now under the head authorship of Tricia Morton, Critical Care Nursing maintains its popular holistic approach to the complexities of adult health and critical care. The Eighth Edition is now in full-color, and has been thoroughly updated to reflect recent changes and advances in critical care nursing. A CD-ROM in the back of this edition has common Critical Care Drug Monographs, Crisis Values of Lab Tests, Critical Care Nursing Procedures, Animations, and comprehensive critical care exams.