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A guide for constructing and using composite indicators for policy makers, academics, the media and other interested parties. In particular, this handbook is concerned with indicators which compare and rank country performance.

The Belmont Report

United States. National Commission for the Protection of Human Subjects of Biomedical and Behavioral Research

Published: 1978

Total Pages: 614


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This book provides an introduction to index numbers for statisticians, economists and numerate members of the public. It covers the essential basics, mixing theoretical aspects with practical techniques to give a balanced and accessible introduction to the subject. The concepts are illustrated by exploring the construction and use of the Consumer Prices Index which is arguably the most important of all official statistics in the UK. The book also considers current issues and developments in the field including the use of large-scale price transaction data. A Practical Introduction to Index Numbers will be the ideal accompaniment for students taking the index number components of the Royal Statistical Society Ordinary and Higher Certificate exams; it provides suggested routes through the book for students, and sets of exercises with solutions.
This book is a most excellent addition to the knowledge base needed to deliver high-quality primary clinical care. It is 10 years since the author last pulled together a collection of the most authoritative clinical guidelines in an easily digestible format. Now a whole plethora of information is available online covering primary to tertiary care which to the busy primary care clinician can be overwhelming. This is therefore no longer a collection of all available guidelines - this is unashamedly a selection of the guidelines relevant to primary care that Dr Smith finds most useful in his dail.
This volume covers all aspects of the antibiotic discovery and development process through Phase II/III. The contributors, a group of highly experienced individuals in both academics and industry, include chapters on the need for new antibiotic compounds, strategies for screening for new antibiotics, sources of novel synthetic and natural antibiotics, discovery phases of lead development and optimization, and candidate compound nominations into development. Beyond discovery , the handbook will cover all of the studies to prepare for IND submission: Phase I (safety and dose ranging), progression to Phase II (efficacy), and Phase III (capturing desired initial indications). This book walks the reader through all aspects of the process, which has never been done before in a single reference. With the rise of antibiotic resistance and the increasing view that a crisis may be looming in infectious diseases, there are strong signs of renewed emphasis in antibiotic research. The purpose of the handbook is to offer a detailed overview of all aspects of the problem posed by antibiotic discovery and development.
A NEW AND ESSENTIAL RESOURCE FOR THE PRACTICE OF EPIDEMIOLOGY AND PUBLIC HEALTH The CDC Field Epidemiology Manual is a definitive guide to investigating acute public health events on the ground and in real time. Assembled and written by experts from the Centers for Disease Control and Prevention as well as other leading public health agencies, it offers current and field-tested guidance for every stage of an outbreak investigation -- from identification to intervention and other core considerations along the way. Modeled after Michael Gregg's seminal book Field Epidemiology, this CDC manual ushers investigators through the core elements of field work, including many of the challenges inherent to outbreaks: working with multiple state and federal agencies or multinational organizations; legal considerations; and effective utilization of an incident-management approach. Additional coverage includes: � Updated guidance for new tools in field investigations, including the latest technologies for data collection and incorporating data from geographic information systems (GIS) � Tips for investigations in unique settings, including healthcare and community-congregate sites � Advice for responding to different types of outbreaks, including acute enteric disease; suspected biologic or toxic agents; and outbreaks of violence, suicide, and other forms of injury For the ever-changing public health landscape, The CDC Field Epidemiology Manual offers a new, authoritative resource for effective outbreak response to acute and emerging threats. *** Oxford University Press will donate a portion of the proceeds from this book to the CDC Foundation, an independent nonprofit and the sole entity created by Congress to mobilize philanthropic and private-sector resources to support the Centers for Disease Control and Prevention's critical health protection work. To learn more about the CDC Foundation, visit www.cdcfoundation.org.
Based on the work of a collection of experts from the laboratory science and quality assurance fields, A Laboratory Quality Handbook of Best Practices and Relevant Regulations provides all of the information needed to run a successful laboratory that is in compliance with all regulations. From sample tracking to accurate documentation, training to methods validation, maintenance to calibration, and out-of-spec responses to preparation for audits, a combination of people, instrumentation and documentation must work in sync for high quality results. This handbook provides information that will help a laboratory achieve high quality results and compliance. Contents: Quality Assurance in the Laboratory, History of Regulation, Training in the Laboratory, Laboratory Documentation and Data, Sample Control and LIM Systems, Methods Validation
Inorganic Controlled Release Technology: Materials and Concepts for Advanced Drug Formulation provides a practical guide to the use and applications of inorganic controlled release technology (iCRT) for drug delivery and other healthcare applications, focusing on newly developed inorganic materials such as bioresorbable glasses and bioceramics. The use of these materials is introduced for a wide range of applications that cover inorganic drug delivery systems for new drug development and the reformulation of existing drugs. The book describes basic concepts, principles, and industrial practices by discussing materials chemistry, physics, nano/microstructure, formulation, materials processing, and case studies, as well as the evaluation and characterization of iCRT systems commonly investigated during industrial R&D. - Provides the first book on inorganic controlled release technology (iCRT), covering key aspects from chemistry, physics, synthetic methods, formulation design, characterization and evaluation - Includes several industry-related case studies to provide practical guidance on how to use iCRT as an alternative to organic polymers systems for both future drug developments and other active ingredient applications - Demonstrates how iCRT offers an unmet business need for improved, controlled release of actives versus traditional CRT systems, which are known to have difficulty with the controlled delivery of both poorly and highly water soluble drug compounds