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Laron syndrome (LS), or primary growth hormone (GH) insensitivity, was first described in 1966. Since then, many patients worldwide have been diagnosed with LS, which involves defects in the GH receptor that cause combined congenital deficiency of GH and IGF-I activities. In this comprehensive book the authors draw upon 50 years of multidisciplinary clinical and investigative follow-up of the large Israeli cohort of LS patients. The genetic basis of the syndrome is fully considered, and all aspects of the pathophysiology of IGF-I deficiency are described. Data derived from the recently generated mouse model of LS are reviewed and compared with the human LS experience. Valuable advice is provided on treatment, and treatment effects, such as metabolic effects, adipose tissue alterations, and impact on aging, are fully explored. Together, this book condenses, consolidates, compares, and contrasts data derived from the human and mouse LS experiences and provides a unique resource for clinical and basic scientists to evaluate and compare IGF-I and GH actions.
Masters Theses in the Pure and Applied Sciences was first conceived, published, and disseminated by the Center for Information and Numerical Data Analysis and Synthesis (CINDAS)* at Purdue University in 1957, starting its coverage of theses with the academic year 1955. Beginning with Volume 13, the printing and dis semination phases of the activity were transferred to University Microfilms/Xerox of Ann Arbor, Michigan, with the thought that such an arrangement would be more beneficial to the academic and general scientific and technical community. After five years of this joint undertaking we had concluded that it was in the interest of all concerned if the printing and distribution of the volumes were handled by an international publishing house to assure improved service and broader dissemination. Hence, starting with Volume 18, Masters Theses in the Pure and Applied Sciences has been disseminated on a worldwide basis by Plenum Publishing Corporation of New York, and in the same year the coverage was broadened to include Canadian universities. All back issues can also be ordered from Plenum. We have reported in Volume 39 (thesis year 1994) a total of 13,953 thesis titles from 21 Canadian and 159 United States universities. We are sure that this broader base for these titles reported will greatly enhance the value of this impor tant annual reference work. While Volume 39 reports theses submitted in 1994, on occasion, certain uni versities do report theses submitted in previous years but not reported at the time.
This lively book examines recent trends in animal product consumption and diet; reviews industry efforts, policies, and programs aimed at improving the nutritional attributes of animal products; and offers suggestions for further research. In addition, the volume reviews dietary and health recommendations from major health organizations and notes specific target levels for nutrients.
The Encyclopedia includes 125 entries, beginning with the origins of genetics including historical background on the work of Gregor Mendel and Charles Darwin, and progressing to the structure of DNA and modern theories such as selfish genes. All branches of genetics are covered, including the genetics of bacteria, viruses, insects, animals and plants, as well as humans. Important topical issues such as the human genome project, bioethics, the law and genetics, genetic disorders, GM crops, and the use of transgenic animals for food and pharmaceutical products are fully surveyed. A section on techniques and biotechnology includes modern methods of analysis, from DNA fingerprinting to the new science of bioinformatics. The articles, all written by specialists, are largely non-mathematical and progress from general concepts to deeper understanding. Each essay is fully referenced, with suggestions for further reading. The text is supplemented by extensive illustrations, tables and a color plate section. The Encyclopedia of Genetics will be a valuable companion for all those working or studying in the various fields of genetical research, and a fascinating reference for all readers with a basic background in biology. Also includes color inserts.
In the past decade, animal scientists have learned that administering recombinantly derived somatotropin (growth hormone) to cows improves milk production and that giving beta-adrenergic agonists to meat animals improves productivity and leanness. In order for these metabolic modifiers to yield benefits, however, sound management of the animals' nutrition is necessary. This volume reports on how these substances work in the animals' metabolism, what effects they might have on nutrient requirements of domestic livestock, and what information should be developed further by investigators. The book explores the current understanding of the biology, structure, mechanisms of action, and treatment effects of somatotropin, beta-adrenergic agonists, and anabolic steroids. A companion volume to the Nutrient Requirements of Domestic Animals series, this authoritative volume will be required reading for animal scientists, researchers, veterinarians, livestock farmers, and faculty and students in university animal veterinary science programs.
List of members in each volume.
"Want to be healthy, vital , alert, and active on your 100th birthday? Then you must read this book." --Dr. Bob Goldman, president, National Academy of Sports Medicine Discover the Age-Reversing Benefits of Human Growth Hormone Lose Fat, Gain Muscle Increase Energy Level Increase Immune Function Enhance Sexual Performance Increase Cardiac Output Improve Skin Elasticity Remove Wrinkles Eliminate Cellulite Improve Vision Increase Memory Retention Improve Quality of Sleep Increase Exercise Performance Lower Blood Pressure Improve Cholesterol Profile Increase Bone Mass Quicken Wound Healing
Sturkie's Avian Physiology is the classic comprehensive single volume on the physiology of domestic as well as wild birds. The Sixth Edition is thoroughly revised and updated, and features several new chapters with entirely new content on such topics as migration, genomics and epigenetics. Chapters throughout have been greatly expanded due to the many recent advances in the field. The text also covers the physiology of flight, reproduction in both male and female birds, and the immunophysiology of birds. The Sixth Edition, like the earlier editions, is a must for anyone interested in comparative physiology, poultry science, veterinary medicine, and related fields. This volume establishes the standard for those who need the latest and best information on the physiology of birds. - Includes new chapters on endocrine disruptors, magnetoreception, genomics, proteomics, mitochondria, control of food intake, molting, stress, the avian endocrine system, bone, the metabolic demands of migration, behavior and control of body temperature - Features extensively revised chapters on the cardiovascular system, pancreatic hormones, respiration, pineal gland, pituitary gland, thyroid, adrenal gland, muscle, gastro-intestinal physiology, incubation, circadian rhythms, annual cycles, flight, the avian immune system, embryo physiology and control of calcium - Stands out as the only comprehensive, single volume devoted to bird physiology - Offers a full consideration of both blood and avian metabolism on the companion website (http://booksite.elsevier.com/ 9780124071605). Tables feature hematological and serum biochemical parameters together with circulating concentrations of glucose in more than 200 different species of wild birds