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This is the second volume in the series of proceedings from the International Workshop on Life Science Grid. It represents the few, if not the only, dedicated proceedings volumes that gathers together the presentations of leaders in the emerging sub-discipline of grid computing for the life sciences. The volume covers the latest developments, trends and trajectories in life science grid computing from top names in bioinformatics and computational biology: A Konagaya; J C Wooley of the National Science Foundation (NSF) and DoE thought leader in supercomputing and life science computing, and one of the key people in the NSF CIBIO initiative; P Arzberger of PRAGMA fame; and R Sinnott of UK e-Science. Sample Chapter(s). Chapter 1: The Grid as a ba for Biomedical Knowledge Creation (155 KB). Contents: The Grid as a OC BaOCO for Biomedical Knowledge Creation (A Konagaya); Cyberinfrastructure for the Biological Sciences (CIBIO) (J C Wooley); Controlling the Chaos: Developing Post-Genomic Grid Infrastructures (R Sinnott & M Bayer); A Framework for Biological Analysis on the Grid (T Okumura et al.); An Architectural Design of Open Genome Services (R Umetsu et al.); Proteome Analysis Using iGAP in Gfarm (W W Li et al.); Large-Scale Simulation and Prediction of HLA-Epitope Complex Structures (A E H Png et al.); Process Integration for Bio-Manufacturing Grid (Z Q Shen et al.); and other papers. Readership: Practitioners of grid computing as applied to the life sciences, life scientists and biologists working on large computational solutions that require grid computing."
Researchers in the ?eld of life sciences rely increasingly on information te- nology to extract and manage relevant knowledge. The complex computational and data management needs of life science research make Grid technologies an attractive support solution. However, many important issues must be addressed before the Life Science Grid becomes commonplace. The 1st International Life Science Grid Workshop (LSGRID 2004) was held in Kanazawa Japan, May 31–June 1, 2004. This workshop focused on life s- ence applications of grid systems especially for bionetwork research and systems biology which require heterogeneous data integration from genome to phenome, mathematical modeling and simulation from molecular to population levels, and high-performance computing including parallel processing, special hardware and grid computing. Fruitful discussions took place through 18 oral presentations, including a keynote address and ?ve invited talks, and 16 poster and demonstration p- sentations in the ?elds of grid infrastructure for life sciences, systems biology, massive data processing, databases and data grids, grid portals and pipelines for functional annotation, parallel and distributed applications, and life science grid projects. The workshop emphasized the practical aspects of grid techno- gies in terms of improving grid-enabled data/information/knowledge sharing, high-performance computing, and collaborative projects. There was agreement among the participants that the advancement of grid technologies for life science research requires further concerted actions and promotion of grid applications. We therefore concluded the workshop with the announcement of LSGRID 2005.
"This book provides methodologies and developments of grid technologies applied in different fields of life sciences"--Provided by publisher.
This is the second volume in the series of proceedings from the International Workshop on Life Science Grid. It represents the few, if not the only, dedicated proceedings volumes that gathers together the presentations of leaders in the emerging sub-discipline of grid computing for the life sciences.The volume covers the latest developments, trends and trajectories in life science grid computing from top names in bioinformatics and computational biology: A Konagaya; J C Wooley of the National Science Foundation (NSF) and DoE thought leader in supercomputing and life science computing, and one of the key people in the NSF CIBIO initiative; P Arzberger of PRAGMA fame; and R Sinnott of UK e-Science.
The only single, up-to-date source for Grid issues in bioinformatics and biology Bioinformatics is fast emerging as an important discipline for academic research and industrial applications, creating a need for the use of Grid computing techniques for large-scale distributed applications. This book successfully presents Grid algorithms and their real-world applications, provides details on modern and ongoing research, and explores software frameworks that integrate bioinformatics and computational biology. Additional coverage includes: * Bio-ontology and data mining * Data visualization * DNA assembly, clustering, and mapping * Molecular evolution and phylogeny * Gene expression and micro-arrays * Molecular modeling and simulation * Sequence search and alignment * Protein structure prediction * Grid infrastructure, middleware, and tools for bio data Grid Computing for Bioinformatics and Computational Biology is an indispensable resource for professionals in several research and development communities including bioinformatics, computational biology, Grid computing, data mining, and more. It also serves as an ideal textbook for undergraduate- and graduate-level courses in bioinformatics and Grid computing.
"This reference presents a vital compendium of research detailing the latest case studies, architectures, frameworks, methodologies, and research on Grid and Cloud Computing"--
During the last decade, national and international scientific organizations have become increasingly engaged in considering how to respond to the biosecurity implications of developments in the life sciences and in assessing trends in science and technology (S&T) relevant to biological and chemical weapons nonproliferation. The latest example is an international workshop, Trends in Science and Technology Relevant to the Biological Weapons Convention, held October 31 - November 3, 2010 at the Institute of Biophysics of the Chinese Academy of Sciences in Beijing. Life Sciences and Related Fields summarizes the workshop, plenary, and breakout discussion sessions held during this convention. Given the immense diversity of current research and development, the report is only able to provide an overview of the areas of science and technology the committee believes are potentially relevant to the future of the Biological and Toxic Weapons Convention (BWC), although there is an effort to identify areas that seemed particularly ripe for further exploration and analysis. The report offers findings and conclusions organized around three fundamental and frequently cited trends in S&T that affect the scope and operation of the convention: The rapid pace of change in the life sciences and related fields; The increasing diffusion of life sciences research capacity and its applications, both internationally and beyond traditional research institutions; and The extent to which additional scientific and technical disciplines beyond biology are increasingly involved in life sciences research. The report does not make recommendations about policy options to respond to the implications of the identified trends. The choice of such responses rests with the 164 States Parties to the Convention, who must take into account multiple factors beyond the project's focus on the state of the science.
This book presents research from many of the major projects involved in the emerging global grid infrastructure. With a particular focus on the practical advantages and applications of grid computing – including real case studies – the book provides an in-depth study of grid technology for a wide range of different needs. Topics: examines a remote instrumentation infrastructure, and a methodology to support e-science applications on e-infrastructures; describes the GEMS storage system, and pipeline workflows for optimizing end-to-end performance in wide-area networks; investigates semantic grid system architecture, social grid agents, and monitoring platforms designed for large-scale distributed systems; explores job control using service-level agreements; introduces the Composable Services Architecture for dynamic service provisioning, and the semantically driven communication middleware platform, Phoenix; discusses the PhyloGrid application, and a numerical simulation performed using grid computing.
The integration of grid, cloud and other e-infrastructures into the fields of biology, bioinformatics, biomedicine, and healthcare are crucial if optimum use is to be made of the latest high-performance and distributed computer technology in these areas. Science gateways are concerned with offering intuitive graphical user interfaces to applications, data, and tools on distributed computing infrastructures. This book presents the joint proceedings of the Tenth HealthGrid Conference and the Fourth International Workshop on Science Gateways for Life Sciences (IWSG-Life), held in Amsterdam, Netherlands in May 2012. The HealthGrid conference promotes the exchange and debate of ideas, technologies and solutions likely to promote the integration of grids into biomedical research and health in the broadest sense. The IWSG-Life workshop series is a forum that brings together scientists from the field of life sciences, bioinformatics, and computer science to advance computational biology and chemistry in the context of science gateways. These events have been jointly organized to maximize the benefit from synergies and stimulate the forging of further links in joint research areas. The book is divided into three parts. Part I includes contributions accepted to the HealthGrid conference; Part II contains the papers about various aspects of the development and usage of science gateways for life sciences. The joint session is recorded in Part III, and addresses the topic of science gateways for biomedical research. The book will provide insights and new perspectives for all those involved in the research and use of infrastructures and technology for healthcare and life sciences.
Unter "Grid Computing" versteht man die gleichzeitige Nutzung vieler Computer in einem Netzwerk für die Lösung eines einzelnen Problems. Grundsätzliche Aspekte und anwendungsbezogene Details zu diesem Gebiet finden Sie in diesem Band. - Grid Computing ist ein viel versprechender Trend, denn man kann damit (1) vorhandene Computer-Ressourcen kosteneffizient nutzen, (2) Probleme lösen, für die enorme Rechenleistungen erforderlich sind, und (3) Synergieeffekte erzielen, auch im globalen Maßstab - Ansatz ist in Forschung und Industrie (IBM, Sun, HP und andere) zunehmend populär (aktuelles Beispiel: Genomforschung) - Buch deckt Motivationen zur Einführung von Grids ebenso ab wie technologische Grundlagen und ausgewählte Beispiele für moderne Anwendungen