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This issue of Neurosurgery Clinics, guest edited by Dr. Michael A. Vogelbaum, is devoted to Glioblastoma, Part I: Surgical Management and Adjuncts. This is one of four issues selected each year by the series Consulting Editors, Russell R. Lonser and Daniel K. Resnick. Articles in this issue include: Perioperative Management of Patients with Glioblastoma, Role of Resection in Glioblastoma Management, Advancing Imaging to Enhance Surgery, Intraoperative Imaging for High-Grade Glioma Surgery, Use of Intraoperative Fluorophores, Extent of Resection of Glioblastoma, Functional Mapping for Glioma Surgery: Preoperative Mapping Tools, Functional Mapping for Glioma Surgery: Intraoperative Mapping Tools, Surgical Adjuncts for Glioblastoma, Window of Opportunity Clinical Trials to Evaluate Novel Therapies for Brain Tumors, Stereotactic Laser Ablation of Glioblastoma, Radiosurgery for Glioblastoma, Challenges Associated with Reoperation in Patients with Glioma, and Surgery for Glioblastoma in Elderly Patients.
This issue of Neurosurgery Clinics, guest edited by Dr. R. Mark Richardson and Dr. Vasileios Kokkinos, will focus on Epilepsy Surgery: The Network Approach. This issue is one of four selected each year by our series consulting editors, Dr. Russell R. Lonser and Dr. Daniel K. Resnick. Topics discussed in this issue will include: History of the network approach in epilepsy surgery, Networks in temporal lobe epilepsy, Networks in frontal lobe epilepsy, Networks in parietal and occipital lobe epilepsy, Structures facilitating epileptogenic network formation, Extracranial interictal and ictal EEG in sEEG planning, Ictal semiology as a tool for sEEG planning, The significance of MRI lesions in sEEG planning, Functional networks in epilepsy presurgical evaluation, Automation advances in sEEG planning, Interpretation of the intracranial sEEG signal, Electrical cortical stimulation, Epileptogenic index, Modeling the epileptogenic network, Machine learning in epilepsy surgery evaluations, Neuromodulation of epilepsy networks, and Decision-making in epilepsy surgery.
This issue of Neurosurgery Clinics, guest edited by Dr. Linda M. Liau, is dedicated to Glioblastoma: Molecular and Clinical Trials. This issue is one of four selected each year by the series consulting editors, Drs. Russell R. Lonser and Daniel K. Resnick. Topics will include—but are not limited to—Pathology & Molecular Markers, Cellular States & Genetic Diversity in Glioblastoma, Mismatch Repair in Glioblastoma Resistance, Genetic Susceptibility in Brain Cancer, Pediatric Gliomas: Molecular Landscape & Emerging Targets, Molecularly Targeted Clinical Trials, Novel Radiation Sensitizers, Immunotherapy Checkpoint Inhibitors, Brain Tumor Vaccines, CAR T Cells, Oncolytic Virotherapy, Targeting Cancer Stem Cells, Therapeutic Delivery to CNS, Theranostics: Dual Modality PET Tracers, and Neuroimaging & Novel Response Assessments.
This issue of Neurosurgery Clinics, guest edited by Dr. Domagoj Coric, provides an Update on Motion Preservation Technologies. This issue is one of four selected each year by our series consulting editors, Drs. Russell R. Lonser and Daniel K. Resnick. This issue discusses state-of-the-art indications, technique, devices, complications and evidence basis for motion preserving technologies in the cervical and lumbar spines. Topics covered in this issue will include: Cervical Total Disc Replacement: Indications and Technique, Cervical Total Disc Replacement: Off-label and Expanded Indications, Cervical Total Disc Replacement: FDA-approved Devices, Cervical Total Disc Replacement: Novel Devices, Cervical Spine Surgery: Arthroplasty versus Fusion versus Posterior Foraminotomy, Cervical Total Disc Replacement: Complications and Complication Avoidance, Cervical Total Disc Replacement: Long-term Outcomes, Biomechanics of Cervical Arthroplasty Devices, Adjacent-level Disease following Spinal Arthroplasty, Lumbar Total Disc Replacement: Current Usage, and Posterior Lumbar Facet Replacement and Arthroplasty.
This issue of Neurosurgery Clinics, guest edited by Drs. Edjah Nduom and Jeff Olson, will focus on Metastases to the Central Nervous System. This issue is one of four selected each year by our series consulting editors, Dr. Russell R. Lonser and Dr. Daniel K. Resnick. Topics discussed in this issue will include: Epidemiology of metastatic CNS disease, Initial approach to the patient with a newly diagnosed solitary brain metastasis, Initial approach to the patient with multiple newly diagnosed brain metastases, When to consider a stereotactic biopsy for brain metastases, Techniques for open surgical resection of cerebral metastases, Laser ablation for cerebral metastases, Histopathological features and laboratory markers of common brain metastases, Recurrence vs radiation necrosis – evaluation and treatment, Anti-epileptic drugs for the management of cerebral metastases, Chemotherapy for the management of cerebral metastases, Approach to the management of metastatic leptomeningeal disease, Immune therapy for CNS metastases, Novel therapeutic targets for the treatment of cerebral metastases, Skull base metastases – diagnosis and management, and more.
This issue of Neurosurgery Clinics, guest edited by Dr. John Hurlbert, is devoted to Current State of the Art in Spinal Cord Injury. This is one of four issues selected each year by the series Consulting Editors, Russell R. Lonser and Daniel K. Resnick. Articles in this issue are dedicated to basics of spinal cord injury and emerging therapy and include topics such as: Pathophysiology of spinal cord injury, Natural history of spinal cord injury, Diagnostic imaging in spinal cord injury, Spinal cord injury clinical assessment tools, Spinal cord injury management on the front line, Central Cord Syndrome redefined, Compartment Syndrome, Hypothermia, Pharmaceutical, Regeneration, and Neural interfacing and modulation.
This issue of Neurosurgery Clinics focus on Intraoperative Imaging. Article topics will include historical, current and future intraoperative imaging modality; iMRI suites: history, design, utility and cost-effectiveness; Stereotactic platforms for iMRI; iMRI for tumor: maximizing extent of resection of glioma; IMRI for tumor: combining iMRI with functional MRI; iMRI for tumor: pituitary adenoma; iMRI for tumor: MR thermometry; iMRI for tumor: LITT for spinal tumors; iMRI for functional/epilepsy neurosurgery: DBS placement; iMRI for functional/epilepsy neurosurgery: MR thermometry for mesial temporal epilepsy; iMRI for functional/epilepsy neurosurgery: MR thermometry HIFU; Fluorescence imaging/agents in tumor resection; Intraoperative 3D ultrasound; Intraoperative 3D CT: spine surgery; Intraoperative 3D CT: cranial/functional/trigem; Intraoperative imaging for vascular lesions; Imaging of intraoperative drug delivery; Intraoperative ultrasound for peripheral nerve; and Intraoperative Raman Spectroscopy.
This issue of Neurosurgery Clinics, guest edited by Drs. Guy McKhann and Hugues Duffau, with consulting editors Russell R. Lonser and Daniel K. Resnick, will focus on Low-Grade Glioma. Topics includes, but are not limited to, Epidemiology and Molecular Epidemiology; WHO Pathological and Molecular Classification; Molecular Pathogenesis; Glioma Cell Migration and Heterogeneity; Clinical Presentation, Natural History, and Prognosis; LGG Epilepsy; MRI, fMRI, DTI, Molecular Imaging; Brain Mapping Techniques in LGG; Surgical Adjuncts to Increase EOR iMRI, Flourescence, Raman Histology; Mapping Cognition and Emotion; Extent of Resection; EOR vs Molecular Classification; Chemotherapy Treatment and Trials; Radiotherapy Treatment and Trials; Higher Order Surgical Questions; and Building a Glioma Practice.
This issue of Neurosurgery Clinics focuses on Controversies in Spinal and Cranial Surgery. Article topics will include:Sacro-illiac Fusion; Interspinous Spacers;Bone Morphogenetic Protein, Platelet Concentrates and Other Biologics; MIS decompression; Pipeline flow diversion in subarachnoid hemorrhage; Direct versus indirect bypass for moyamoya disease; Management of prenatally diagnosed myelomeningocele; Management of incidental aneurysm; Surgical management of incidental low-grade glioma; and more!
This second edition presents core clinical neuroanesthesia and neurointensive care knowledge in a practical, user-friendly format.