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A Nobel Prize–winning cancer biologist, leader of major scientific institutions, and scientific adviser to President Obama reflects on his remarkable career. A PhD candidate in English literature at Harvard University, Harold Varmus discovered he was drawn instead to medicine and eventually found himself at the forefront of cancer research at the University of California, San Francisco. In this “timely memoir of a remarkable career” (American Scientist), Varmus considers a life’s work that thus far includes not only the groundbreaking research that won him a Nobel Prize but also six years as the director of the National Institutes of Health; his current position as the president of the Memorial Sloan-Kettering Cancer Center; and his important, continuing work as scientific adviser to President Obama. From this truly unique perspective, Varmus shares his experiences from the trenches of politicized battlegrounds ranging from budget fights to stem cell research, global health to science publishing.
We’ve been led to believe that when we get sick, it’s our genetics. Or it’s just bad luck—and doctors alone hold the keys to optimal health. For years, Lissa Rankin, M.D., believed the same. But when her own health started to suffer, and she turned to Western medical treatments, she found that they not only failed to help; they made her worse. So she decided to take matters into her own hands. Through her research, Dr. Rankin discovered that the health care she had been taught to practice was missing something crucial: a recognition of the body’s innate ability to self-repair and an appreciation for how we can control these self-healing mechanisms with the power of the mind. In an attempt to better understand this phenomenon, she explored peer-reviewed medical literature and found evidence that the medical establishment had been proving that the body can heal itself for over 50 years. Using extraordinary cases of spontaneous healing, Dr. Rankin shows how thoughts, feelings, and beliefs can alter the body’s physiology. She lays out the scientific data proving that loneliness, pessimism, depression, fear, and anxiety damage the body, while intimate relationships, gratitude, meditation, sex, and authentic self-expression flip on the body’s self-healing processes. In the final section of the book, you’ll be introduced to a radical new wellness model based on Dr. Rankin’s scientific findings. Her unique six-step program will help you uncover where things might be out of whack in your life—spiritually, creatively, environmentally, nutritionally, and in your professional and personal relationships—so that you can create a customized treatment plan aimed at bolstering these health-promoting pieces of your life. You’ll learn how to listen to your body’s "whispers" before they turn to life-threatening "screams" that can be prevented with proper self-care, and you’ll learn how to trust your inner guidance when making decisions about your health and your life. By the time you finish Mind Over Medicine, you’ll have made your own Diagnosis, written your own Prescription, and created a clear action plan designed to help you make your body ripe for miracles.
The next time you get sick, consider this before picking up the aspirin: your body may be doing exactly what it's supposed to. In this ground-breaking book, two pioneers of the science of Darwinian medicine argue that illness as well as the factors that predispose us toward it are subject to the same laws of natural selection that otherwise make our bodies such miracles of design. Among the concerns they raise: When may a fever be beneficial? Why do pregnant women get morning sickness? How do certain viruses "manipulate" their hosts into infecting others? What evolutionary factors may be responsible for depression and panic disorder? Deftly summarizing research on disorders ranging from allergies to Alzheimer's, and form cancer to Huntington's chorea, Why We Get Sick, answers these questions and more. The result is a book that will revolutionize our attitudes toward illness and will intrigue and instruct lay person and medical practitioners alike.
Essential, required reading for doctors and patients alike: A Pulitzer Prize-winning author and one of the world’s premiere cancer researchers reveals an urgent philosophy on the little-known principles that govern medicine—and how understanding these principles can empower us all. Over a decade ago, when Siddhartha Mukherjee was a young, exhausted, and isolated medical resident, he discovered a book that would forever change the way he understood the medical profession. The book, The Youngest Science, forced Dr. Mukherjee to ask himself an urgent, fundamental question: Is medicine a “science”? Sciences must have laws—statements of truth based on repeated experiments that describe some universal attribute of nature. But does medicine have laws like other sciences? Dr. Mukherjee has spent his career pondering this question—a question that would ultimately produce some of most serious thinking he would do around the tenets of his discipline—culminating in The Laws of Medicine. In this important treatise, he investigates the most perplexing and illuminating cases of his career that ultimately led him to identify the three key principles that govern medicine. Brimming with fascinating historical details and modern medical wonders, this important book is a fascinating glimpse into the struggles and Eureka! moments that people outside of the medical profession rarely see. Written with Dr. Mukherjee’s signature eloquence and passionate prose, The Laws of Medicine is a critical read, not just for those in the medical profession, but for everyone who is moved to better understand how their health and well-being is being treated. Ultimately, this book lays the groundwork for a new way of understanding medicine, now and into the future.
"Although physicians make use of science, this book argues that medicine is not itself a science, but rather an interpretive practice that relies heavily on clinical reasoning." "In How Doctors Think, Kathryn Montgomery contends that assuming medicine is strictly a science can have adverse effects. She suggests these can be significantly reduced by recognizing the vital role of clinical judgment."--BOOK JACKET.
This classic MUP text discusses the historical development of science, technology and medicine in Western Europe and North America from the Renaissance to the present. Combining theoretical discussion and empirical illustration, it redefines the geography of science, technology and medicine.
The nature of scientific activity has changed dramatically over the last half century, and the objectivity and rigorous search for evidence that once defined it are being abandoned. Increasingly, this text argues, dogma has taken the place of authentic science. This study examines how conflicts of interest--both institutional and individual--have become pervasive in the science world, and also explores the troubling state of research funding and flaws of the peer-review process. It looks in depth at the dominance of several specific theories, including the Big Bang cosmology, human-caused global warming, HIV as a cause of AIDS, and the efficacy of anti-depressant drugs. In a scientific environment where distinguished experts who hold contrary views are shunned, this book is an important contribution to the examination of scientific heterodoxies.
There is a growing interest in studies that document the relationship between science and medicine - as ideas, practices, technologies and outcomes - across cultural, national, geographic terrain. Tibetan medicine is not only known as a scholarly medical tradition among other Asian medical systems, with many centuries of technological, clinical, and pharmacological innovation; it also survives today as a complex medical resource across many Asian nations - from India and Bhutan to Mongolia, Tibet (TAR) and China, Buryatia - as well as in Western Europe and the Americas. The contributions to this volume explore, in equal measure, the impacts of western science and biomedicine on Tibetan grounds - i.e., among Tibetans across China, the Himalaya and exile communities as well as in relation to globalized Tibetan medicine - and the ways that local practices change how such “science” gets done, and how this continually hybridized medical knowledge is transmitted and put into practice. As such, this volume contributes to explorations into the bi-directional flows of medical knowledge and practice.
One of the pathways by which the scientific community confirms the validity of a new scientific discovery is by repeating the research that produced it. When a scientific effort fails to independently confirm the computations or results of a previous study, some fear that it may be a symptom of a lack of rigor in science, while others argue that such an observed inconsistency can be an important precursor to new discovery. Concerns about reproducibility and replicability have been expressed in both scientific and popular media. As these concerns came to light, Congress requested that the National Academies of Sciences, Engineering, and Medicine conduct a study to assess the extent of issues related to reproducibility and replicability and to offer recommendations for improving rigor and transparency in scientific research. Reproducibility and Replicability in Science defines reproducibility and replicability and examines the factors that may lead to non-reproducibility and non-replicability in research. Unlike the typical expectation of reproducibility between two computations, expectations about replicability are more nuanced, and in some cases a lack of replicability can aid the process of scientific discovery. This report provides recommendations to researchers, academic institutions, journals, and funders on steps they can take to improve reproducibility and replicability in science.
Why was there a meltdown at the Fukushima power plant? Why do some people get cancer and not others? Why is global warming happening? Why does one person get depressed in the face of life's vicissitudes while another finds resilience? Questions like these—questions of causality—form the basis of modern scientific inquiry, posing profound intellectual and methodological challenges for researchers in the physical, natural, biomedical, and social sciences. In this groundbreaking book, noted psychiatrist and author Peter Rabins offers a conceptual framework for analyzing daunting questions of causality. Navigating a lively intellectual voyage between the shoals of strict reductionism and relativism, Rabins maps a three-facet model of causality and applies it to a variety of questions in science, medicine, economics, and more. Throughout this book, Rabins situates his argument within relevant scientific contexts, such as quantum mechanics, cybernetics, chaos theory, and epigenetics. A renowned communicator of complex concepts and scientific ideas, Rabins helps readers stretch their minds beyond the realm of popular literary tipping points, blinks, and freakonomic explanations of the world.