Helmut Sigel
Published: 1988-03-30
Total Pages: 538
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Metal Ions in Biological Systems is devoted to increasing our understanding of the relationship between the chemistry of metals and life processes. The volumes reflect the interdisciplinary nature of bioinorganic chemistry and coordinate the efforts of researchers in the fields of biochemistry, inorganic chemistry, coordination chemistry, environmental chemistry, biophysics, pharmacy, and medicine. Volumes deal with such topics as the formation, stability, structure, and reactivity of biological compounds of low and high molecular weight containing metal ions; the metabolism and transport of metal ions and their complexes; and new models of complicated natural structures and processes. Devoted solely to the vibrant research area of nickel and its role in biology, Volume 23 offers a comprehensive account of this important subject from the perspectives of 24 distinguished, international authorities. In 11 stimulating, in-depth chapters, Nickel and Its Role in Biology covers nickel and its function in the environment, in aquatic systems, in plants, as well as its metabolism in man and animals ... treats nickel ion binding to amino acids and peptides ... examines nickel in proteins and enzymes, including hydrogenases ... considers the interaction of nickel with nucleic acids and their constituents ... displays thoroughly the toxicology of nickel compounds ... and describes the analysis of nickel in biological materials. With more than 1,400 references to assist further research, Nickel and Its Role in Biology is an essential resource for scientists and students in several disciplines, including biochemistry; bioinorganic, inorganic, and coordination chemistry; biophysics; molecular biology; enzymology; pharmacology; clinical chemistry; nutrition; and toxicology. Book jacket.