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This book offers a complete discussion of product development in the pharmaceutical and biotechnology industries from discovery, to product launch, through life cycle management. The book is organized for optimal usefulness in the education and training of health care professionals (MD, PharmD, PhD), at universities. The format is a set of figures, tables and lists, along with detailed narrative descriptions, including real-life examples, illustrations, controversies in industry, and references. The editors and authors of the book are industry and research experts in a variety of disciplines.
Musculoskeletal diseases are rapidly becoming a major health concern. The incidence of osteoarthritis, the most common arthritic disorder, is increasing steadily due to the graying of the world population. This disease is responsible of human life, a time in for significant morbidity, particularly in the second half which the quality of life is of primary importance. The aim of this publication is to bring to physicians and scientists a comprehensive overview of the field, from molecules to men. The direct costs related to osteoarthritis have been increasing steadily over the years and will soon be comparable to those of other major illnesses, such as cardiovascular diseases. This, of course, does not take into account all of the other costs related to the disease which often cannot be simply calculated in dollars and cents. There has been a great deal of renewed interest in osteoarthritis in the last few decades. This has been brought on by the need to improve our knowledge of all aspects of the disease, especially with regard to its etiopathogenesis and treatment. The most recent findings and developments on the structural, bio chemical, biomechanical and molecular changes observed in clinical and ex perimental osteoarthritis are presented in this book.
This book focuses on the impacts of the built environment, and how to predict and measure the benefits and consequences of changes taking place to address sustainability in the development and building industries. It draws together the best treatments of these subjects from the Leeds Sustainability Institute’s inaugural International Conference on Sustainability, Ecology, Engineering, Design for Society (SEEDS). The focus of discussion is on understanding how buildings and spaces are designed and nurtured to obtain optimal outcomes in energy efficiency and environmental impacts. In addition to examining technical issues such as modeling energy performance, emphasis is placed on the health and well-being of occupants. This holistic approach addresses the interdependence of people with the built and natural environments. The book’s contents reflect the interdisciplinary and international collaboration critical to assembly of the knowledge required for positive change.
Descreve como a corrupção é julgada na arbitragem comercial internacional. Procura explicar porque não há uma uniformidade na política arbitral em relação à corrupção. Analisa casos relativos à corrupção e arbitragem. Examina a legislação sobre corrupção, assim como convenções internacionais relevantes.
Delivering an encompassing overview of the factors, varieties, and applications determining product containment, this concise reference provides authoritative information on containment processes. It reviews the historical context, definition, evolution, and application of containment technology, analyzes a variety of containment techniques in new