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This book provides insights into the principles of operation of the cerebral cortex. These principles are key to understanding how we, as humans, function. The book includes Appendices on the operation of many of the neuronal networks described in the book, together with simulation software written in Matlab.
This updated edition covers a range of new topics, including stress and the immune system, post-traumatic stress and crisis intervention, Eye Movement Desensitization and Reprocessing (EMDR), Critical Incident Stress Debriefing (CISD), Crisis Management Briefings in response to mass disasters and terrorism, Critical Incident Stress Management (CISM), spirituality and religion as stress management tools, dietary factors and stress, and updated information on psychopharmacologic intervention in the human stress response. It is a comprehensive and accessible guide for students, practitioners, and researchers in the fields of psychology, psychiatry, medicine, nursing, social work, and public health.
Monika Fludernik presents a detailed analysis of free indirect discourse as it relates to narrative theory, and the crucial problematic of how speech and thought are represented in fiction. Building on the insights of Ann Banfield's Unspeakable Sentences, Fludernik radically extends Banfield's model to accommodate evidence from conversational narrative, non-fictional prose and literary works from Chaucer to the present. Fludernik's model subsumes earlier insights into the forms and functions of quotation and aligns them with discourse strategies observable in the oral language. Drawing on a vast range of literature, she provides an invaluable resource for researchers in the field and introduces English readers to extensive work on the subject in German as well as comparing the free indirect discourse features of German, French and English. This study effectively repositions the whole area between literature and linguistics, opening up a new set of questions in narrative theory.
David Fisher, MD, PhD, and an authoritative panel of academic, cutting-edge researchers review and summarize the current state of the field. Describing the broad roles of tumor suppressors from a perspective based in molecular biology and genetics, the authors detail the major suppressors and the pathways they regulate, including cell cycle progression, stress responses, apoptosis, and responses to DNA damage. Leading-edge and forward-looking, Tumor Suppressor Genes in Human Cancer illuminates what is currently known of tumor suppressor genes and their regulation, work that is already beginning to revolutionize cancer target elucidation, drug discovery, and treatment design.
This book is about nature considered as the totality of physical existence, the universe, and our present day attempts to understand it. If we see the universe as a network of networks of computational processes at many different levels of organization, what can we learn about physics, biology, cognition, social systems, and ecology expressed through interacting networks of elementary particles, atoms, molecules, cells, (and especially neurons when it comes to understanding of cognition and intelligence), organs, organisms and their ecologies? Regarding our computational models of natural phenomena Feynman famously wondered: “Why should it take an infinite amount of logic to figure out what one tiny piece of space/time is going to do?” Phenomena themselves occur so quickly and automatically in nature. Can we learn how to harness nature’s computational power as we harness its energy and materials? This volume includes a selection of contributions from the Symposium on Natural Computing/Unconventional Computing and Its Philosophical Significance, organized during the AISB/IACAP World Congress 2012, held in Birmingham, UK, on July 2-6, on the occasion of the centenary of Alan Turing’s birth. In this book, leading researchers investigated questions of computing nature by exploring various facets of computation as we find it in nature: relationships between different levels of computation, cognition with learning and intelligence, mathematical background, relationships to classical Turing computation and Turing’s ideas about computing nature - unorganized machines and morphogenesis. It addresses questions of information, representation and computation, interaction as communication, concurrency and agent models; in short this book presents natural computing and unconventional computing as extension of the idea of computation as symbol manipulation.