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This book covers 3D printing activities by fused deposition modeling process. The two introductory chapters discuss the principle, types of machines and raw materials, process parameters, defects, design variations and simulation methods. Six chapters are devoted to experimental work related to process improvement, mechanical testing and characterization of the process, followed by three chapters on post-processing of 3D printed components and two chapters addressing sustainability concerns. Seven chapters discuss various applications including composites, external medical devices, drug delivery system, orthotic inserts, watertight components and 4D printing using FDM process. Finally, six chapters are dedicated to the study on modeling and optimization of FDM process using computational models, evolutionary algorithms, machine learning, metaheuristic approaches and optimization of layout and tool path.
In this book, fused deposition modeling (FDM) is described with focus on product quality control and enhancement. The book begins by introducing the basics of FDM and its associated process parameters. Then, strategies for quality control and enhancement are described using case studies of both original results by the authors and from published literature. Resolution and print orientation, multi-objective optimizations and surface engineering are identified and discussed as the strategies for enhancing the quality of FDM products in this book.
This book presents the outcomes from the 2nd International Conference on Marine and Advanced Technologies 2021 (Icmat2021) which was organized by the Research and Innovation section, University Kuala Lumpur - Malaysian Institute of Marine Engineering Technology. The theme “Propelling to the Innovative Idea” highlights prominence of recent developments in marine and advanced technologies in the field of marine application, maritime operation, energy and reliability, advanced materials and applied science. This online conference provided a platform for presentations and discussions at the local and international level between educationists, researchers, students, and industrialists. Furthermore, it created opportunities to establish networks and meet experts in addition to exchange of up-to-date knowledge in the field. This book is the up-to-date reference, especially to those who want to learn and explore more about the latest developments and technologies of maritime industries.
Affordable 3D printers are rapidly becoming everyday additions to the desktops and worktables of entertainment design practitioners – whether working in theatre, theme parks, television and film, museum design, window displays, animatronics, or... you name it! We are beginning to ask important questions about these emerging practices: · How can we use 3D fabrication to make the design and production process more efficient? · How can it be used to create useful and creative items? · Can it save us from digging endlessly through thrift store shelves or from yet another late-night build? · And when budgets are tight, will it save us money? This quick start guide will help you navigate the alphabet soup that is 3D printing and begin to answer these questions for yourself. It outlines the basics of the technology, and its many uses in entertainment design. With straightforward and easy-to-follow information, you will learn ways to acquire printable 3D models, basic methods of creating your own, and tips along the way to produce successful prints. Over 70 professionals contributed images, guidance, and never-before-seen case studies filled with insider secrets to this book, including tutorials by designer and pioneer, Owen M. Collins.
This book is a printed edition of the Special Issue "3D Printed Microfluidic Devices" that was published in Micromachines
3D printing is forecast to revolutionise the pharmaceutical sector, changing the face of medicine development, manufacture and use. Potential applications range from pre-clinical drug development and dosage form design through to the fabrication of functionalised implants and regenerative medicine. Within clinical pharmacy practice, printing technologies may finally lead to the concept of personalised medicines becoming a reality. This volume aims to be the definitive resource for anyone thinking of developing or using 3D printing technologies in the pharmaceutical sector, with a strong focus on the translation of printing technologies to a clinical setting. This text brings together leading experts to provide extensive information on an array of 3D printing techniques, reviewing the current printing technologies in the pharmaceutical manufacturing supply chain, in particular, highlighting the state-of-the-art applications in medicine and discussing modern drug product manufacture from a regulatory perspective. This book is a highly valuable resource for a range of demographics, including academic researchers and the pharmaceutical industry, providing a comprehensive inventory detailing the current and future applications of 3D printing in pharmaceuticals. Abdul W. Basit is Professor of Pharmaceutics at the UCL School of Pharmacy, University College London. Abdul’s research sits at the interface between pharmaceutical science and gastroenterology, forging links between basic science and clinical outcomes. He leads a large and multidisciplinary research group, and the goal of his work is to further the understanding of gastrointestinal physiology by fundamental research. So far, this knowledge has been translated into the design of new technologies and improved disease treatments, many of which are currently in late-stage clinical trials. He has published over 350 papers, book chapters and abstracts and delivered more than 250 invited research presentations. Abdul is also a serial entrepreneur and has filed 25 patents and founded 3 pharmaceutical companies (Kuecept, Intract Pharma, FabRx). Abdul is a frequent speaker at international conferences, serves as a consultant to many pharmaceutical companies and is on the advisory boards of scientific journals, healthcare organisations and charitable bodies. He is the European Editor of the International Journal of Pharmaceutics. Abdul was the recipient of the Young Investigator Award in Pharmaceutics and Pharmaceutical Technology from the American Association of Pharmaceutical Scientists (AAPS) and is the only non-North American scientist to receive this award. He was also the recipient of the Academy of Pharmaceutical Sciences (APS) award. Simon Gaisford holds a Chair in Pharmaceutics and is Head of the Department of Pharmaceutics at the UCL School of Pharmacy, University College London. He has published 110 papers, 8 book chapters and 4 authored books. His research is focused on novel technologies for manufacturing medicines, particularly using ink-jet printing and 3D printing, and he is an expert in the physico-chemical characterisation of compounds and formulations with thermal methods and calorimetry.
Hot-melt extrusion (HME) - melting a substance and forcing it through an orifice under controlled conditions to form a new material - is an emerging processing technology in the pharmaceutical industry for the preparation of various dosage forms and drug delivery systems, for example granules and sustained release tablets. Hot-Melt Extrusion: Pharmaceutical Applications covers the main instrumentation, operation principles and theoretical background of HME. It then focuses on HME drug delivery systems, dosage forms and clinical studies (including pharmacokinetics and bioavailability) of HME products. Finally, the book includes some recent and novel HME applications, scale -up considerations and regulatory issues. Topics covered include: principles and die design of single screw extrusion twin screw extrusion techniques and practices in the laboratory and on production scale HME developments for the pharmaceutical industry solubility parameters for prediction of drug/polymer miscibility in HME formulations the influence of plasticizers in HME applications of polymethacrylate polymers in HME HME of ethylcellulose, hypromellose, and polyethylene oxide bioadhesion properties of polymeric films produced by HME taste masking using HME clinical studies, bioavailability and pharmacokinetics of HME products injection moulding and HME processing for pharmaceutical materials laminar dispersive & distributive mixing with dissolution and applications to HME technological considerations related to scale-up of HME processes devices and implant systems by HME an FDA perspective on HME product and process understanding improved process understanding and control of an HME process with near-infrared spectroscopy Hot-Melt Extrusion: Pharmaceutical Applications is an essential multidisciplinary guide to the emerging pharmaceutical uses of this processing technology for researchers in academia and industry working in drug formulation and delivery, pharmaceutical engineering and processing, and polymers and materials science. This is the first book from our brand new series Advances in Pharmaceutical Technology. Find out more about the series here.
Machining and Tribology provides insight into both the role of tribology in machining and the effects of various machining processes on tribology, exploring topics such as machining mechanisms, coolant technology, tool wear, and more. Covering the latest research, the book starts by looking at the tribological aspects of turning, milling, and drilling processes. From there, it explores the effects of different coolants such as flood, minimum quantity lubrication, and cryogenics on machining forces, tool wear, friction, chip formation, and surface generation during various machining processes. Tribological considerations of machined components follow, and the volume concludes with chapters covering simulation scenarios for predicting machining forces, tool wear, surface generation, and chip formation. - Draws upon the science of tribology to better understand, predict, and improve machining processes - Covers tribology in different types of machining such as turning, milling, grinding, abrasive jet machining, and others - Explores the underlying mechanisms of coolant contributions on machining processes - Applies simulation techniques to explore the mechanism of nano-machining
This book covers in detail the various aspects of joining materials to form parts. A conceptual overview of rapid prototyping and layered manufacturing is given, beginning with the fundamentals so that readers can get up to speed quickly. Unusual and emerging applications such as micro-scale manufacturing, medical applications, aerospace, and rapid manufacturing are also discussed. This book provides a comprehensive overview of rapid prototyping technologies as well as support technologies such as software systems, vacuum casting, investment casting, plating, infiltration and other systems. This book also: Reflects recent developments and trends and adheres to the ASTM, SI, and other standards Includes chapters on automotive technology, aerospace technology and low-cost AM technologies Provides a broad range of technical questions to ensure comprehensive understanding of the concepts covered
This book presents a selection of papers on advanced technologies for 3D printing and additive manufacturing, and demonstrates how these technologies have changed the face of direct, digital technologies for the rapid production of models, prototypes and patterns. Because of their wide range of applications, 3D printing and additive manufacturing technologies have sparked a powerful new industrial revolution in the field of manufacturing. The evolution of 3D printing and additive manufacturing technologies has changed design, engineering and manufacturing processes across such diverse industries as consumer products, aerospace, medical devices and automotive engineering. This book will help designers, R&D personnel, and practicing engineers grasp the latest developments in the field of 3D Printing and Additive Manufacturing.