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Lyrical, inspiring, and affecting text paired with bright, appealing illustrations make Ready to Fly perfect for aspiring ballerinas everywhere who are ready to leap and to spread their wings! Ready to Fly is the true story of Sylvia Townsend, an African American girl who falls in love with ballet after seeing Swan Lake on TV. This nonfiction picture book is an excellent choice to share at home or in the classroom. Although there aren’t many ballet schools that will accept a girl like Sylvia in the 1950s, her local bookmobile provides another possibility. A librarian helps Sylvia find a book about ballet and the determined seven-year-old, with the help of her new books, starts teaching herself the basics of classical ballet. Soon Sylvia learns how to fly—how to dance—and how to dare to dream. Includes a foreword from Sylvia Townsend, a brief history of the bookmobile, an author’s note, and a further reading list.
The troubles of the airline system have become acute in the post-terrorist era. As the average cost of a flight has come down in the last twenty years, the airlines have survived by keeping planes full and funneling traffic through a centralized hub-and-spoke routing system. Virtually all of the technological innovation in airplanes in the last thirty years has been devoted to moving passengers more efficiently between major hubs. But what was left out of this equation was the convenience and flexibility of the average traveler. Now, because of heightened security, hours of waiting are tacked onto each trip. As James Fallows vividly explains, a technological revolution is under way that will relieve this problem. Free Flight features the stories of three groups who are inventing and building the future of all air travel: NASA, Cirrus Design in Duluth, Minnesota, and Eclipse Aviation in Albuquerque, New Mexico. These ventures should make it possible for more people to travel the way corporate executives have for years: in small jet planes, from the airport that's closest to their home or office directly to the airport closest to where they really want to go. This will be possible because of a product now missing from the vast array of flying devices: small, radically inexpensive jet planes, as different from airliners as personal computers are from mainframes. And, as Fallows explains in a new preface, a system that avoids the congestion of the overloaded hub system will offer advantages in speed, convenience, and especially security in the new environment of air travel.
A complete concordance or verbal index to words, phrases and passages in the dramatic works of Shakespeare. There is also a supplementary concordance to the poems. This is an essential reference work for all students and readers of Shakespeare.
Sometimes, it can feel as though we are living in the worst of times--a world of chaos, uncertainty, and breakdown. But could this also be the best of times--a crucible of change in which a wiser and more spiritually mature future is being forged? The stars are most clearly visible in the deepest darkness. The butterfly emerges out of the worst meltdown of the chrysalis. In Born to Fly, Margaret Silf helps us to explore what it would mean for each of us to be such an emerging butterfly--to be an agent of spiritual transformation in our own lives and in the world around us. What kind of future do we desire for ourselves, for those who follow after us, and for the whole of creation? And, if the choices we make today are shaping that future, how might we learn to make those choices more wisely? The second part of the book takes us on a gentle journey in five stages through the process of transformation mapped out for us by the caterpillar as it changes from a pesky garden grub, taking what it wants without regard for the rest of creation, to a butterfly, giving life wherever it lands. Born to Fly is designed to be read for personal reflection and inspiration, or alongside fellow readers, with suggestions for further discussion. It is a companion book to Margaret Silf's Hidden Wings.
The fruit fly Drosophila melanogaster is an established tool to study mechanisms of innate immunity. Drosophila flies and larvae launch elegant humoral and cellular innate immune responses against bacteria, viruses, fungi and parasites. The humoral immune response is based on microbial recognition primarily by peptidoglycan recognition proteins leading to the production of antimicrobial peptides (AMPs). In the past few decades, Drosophilists have dissected how flies react to systemic bacterial and fungal infections at the molecular level and shown how these mechanisms are conserved from human to man. Fly humoral immune response is mainly mediated by two evolutionarily conserved NF-κB signaling pathways, the Toll and the Immune deficiency (Imd) pathways. The discovery of the Toll receptor as a key regulator of immune response, first in cultured Drosophila cells and then in Drosophila in vivo, formed the basis of the Toll-Like Receptor (TLR) research in humans and mammals. More recently, this field has broadened considerably, including e.g. the antimicrobial responses taking place in the gut. Another interesting aspect related to innate immunity is the antiviral immune mechanisms found in Drosophila. Best understood are the mechanisms based on RNAi, primarily against RNA virus infections. More recently, the evolutionarily conserved molecule STING has been shown to integrate responses against both viruses and bacteria.