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Ultrafast lasers allow high-precision imaging and manipulation for biological and medical applications. Nonlinear optical microscopy has provided researchers with unique possibilities of three-dimensional imaging of biological cells and tissues. Nonlinear optical imaging technique is a rapidly emerging research area with widespread fundamental research and clinical applications. Nonlinear optical imaging allows both structural and functional imaging with cellular level resolution imaging in biological systems. The introduction of endogenous or exogenous probes can selectively enhance contrast for molecular targets in a living cell as well as supply functional information on processes. With the aim to control nonlinear optical processes and to obtain functional images, nonlinear optical processes can be controlled by photo-controlled probes and/or parameters of ultrafast laser pulses, such as time, space, polarization, and phase. This book gives an overview of the nonlinear optical process by ultrafast laser pulses and explains how the basics of nonlinear optical microscopy led to the most advanced techniques of photo-controlled nonlinear optical microscopy.
Second-harmonic generation (SHG) microscopy has shown great promise for imaging live cells and tissues, with applications in basic science, medical research, and tissue engineering. Second Harmonic Generation Imaging offers a complete guide to this optical modality, from basic principles, instrumentation, methods, and image analysis to biomedical a
The Optical Society of America (OSA) and SPIE – The International Society for Optical Engineering have awarded Robert Boyd with an honorable mention for the Joseph W. Goodman Book Writing Award for his work on Nonlinear Optics, 2nd edition.Nonlinear optics is essentially the study of the interaction of strong laser light with matter. It lies at the basis of the field of photonics, the use of light fields to control other light fields and to perform logical operations. Some of the topics of this book include the fundamentals and applications of optical systems based on the nonlinear interaction of light with matter. Topics to be treated include: mechanisms of optical nonlinearity, second-harmonic and sum- and difference-frequency generation, photonics and optical logic, optical self-action effects including self-focusing and optical soliton formation, optical phase conjugation, stimulated Brillouin and stimulated Raman scattering, and selection criteria of nonlinear optical materials.· Covers all the latest topics and technology in this ever-evolving area of study that forms the backbone of the major applications of optical technology· Offers first-rate instructive style making it ideal for self-study· Emphasizes the fundamentals of non-linear optics rather than focus on particular applications that are constantly changing
This new edition features numerous updates and additions. Especially 4 new chapters on Fiber Optics, Integrated Optics, Frequency Combs and Interferometry reflect the changes since the first edition. In addition, major complete updates for the chapters: Optical Materials and Their Properties, Optical Detectors, Nanooptics, and Optics far Beyond the Diffraction Limit. Features Contains over 1000 two-color illustrations. Includes over 120 comprehensive tables with properties of optical materials and light sources. Emphasizes physical concepts over extensive mathematical derivations. Chapters with summaries, detailed index Delivers a wealth of up-to-date references.
Since the 3rd edition appeared, a fast evolution of the field has occurred. The fourth edition of this classic work provides an up-to-date account of the nonlinear phenomena occurring inside optical fibers. The contents include such important topics as self- and cross-phase modulation, stimulated Raman and Brillouin scattering, four-wave mixing, modulation instability, and optical solitons. Many new figures have been added to help illustrate the concepts discussed in the book. New to this edition are chapters on highly nonlinear fibers and and the novel nonlinear effects that have been observed in these fibers since 2000. Such a chapter should be of interest to people in the field of new wavelengths generation, which has potential application in medical diagnosis and treatments, spectroscopy, new wavelength lasers and light sources, etc. Continues to be industry bestseller providing unique source of comprehensive coverage on the subject of nonlinear fiber optics Fourth Edition is a completely up-to-date treatment of the nonlinear phenomena occurring inside optical fibers Includes 2 NEW CHAPTERS on the properties of highly nonlinear fibers and their novel nonlinear effects
Sol--Gel--Optics encompasses numerous schemes for fabricating optical materials from gels -- materials such as bulk optics, optical waveguides, doped oxides for laser and nonlinear optics, gradient refractive index (GRIN) optics, chemical sensors, environmental sensors, and `smart' windows. Sol--Gel--Optics: Processing and Applications provides in-depth coverage of the synthesis and fabrication of these materials and discusses the optics related to microporous, amorphous, crystalline and composite materials. The reader will also find in this book detailed descriptions of new developments in silica optics, bulk optics, waveguides and thin films. Various applications to sensor and device technology are highlighted. For researchers and students looking for novel optical materials, processing methods or device ideas, Sol--Gel--Optics: Processing and Applications surveys a wide array of promising new avenues for further investigation and for innovative applications. (This book is the first in a new subseries entitled `Electronic Materials: Science and Technology).
These are exciting times for the field of optical imaging of brain function. Rapid developments in theory and technology continue to considerably advance understanding of brain function. Reflecting changes in the field during the past five years, the second edition of In Vivo Optical Imaging of Brain Function describes state-of-the-art techniques and their applications for the growing field of functional imaging in the live brain using optical imaging techniques. New in the Second Edition: Voltage-sensitive dyes imaging in awake behaving animals Imaging based on genetically encoded probes Imaging of mitochondrial auto-fluorescence as a tool for cortical mapping Using pH-sensitive dyes for functional mapping Modulated imaging Calcium imaging of neuronal activity using 2-photon microscopy Fourier approach to optical imaging Fully updated chapters from the first edition Leading Authorities Explore the Latest Techniques Updated to reflect continuous development in this emerging research area, this new edition, as with the original, reaches across disciplines to review a variety of non-invasive optical techniques used to study activity in the living brain. Leading authorities from such diverse areas as biophysics, neuroscience, and cognitive science present a host of perspectives that range from a single neuron to large assemblies of millions of neurons, captured at various temporal and spatial resolutions. Introducing techniques that were not available just a few years ago, the authors describe the theory, setup, analytical methods, and examples that highlight the advantages of each particular method.
Optical Bistability: Controlling Light with Light focuses on optical bistability in nonlinear optical systems. Emphasis is on passive (non-laser) systems that exhibit reversible bistability with input intensity as the hysteresis variable, along with the physics and the potential applications of such systems for nonlinear optical signal processing. This book consists of seven chapters and begins with a historical overview of optical bistability in lasers and passive systems. The next chapter describes steady-state theories of optical bistability, including the Bonifacio-Lugiato model, as well as the boundary conditions of an optical cavity and the coupled Maxwell-Bloch equations. Both intrinsic and hybrid experiments are then described, along with light-by-light control, pulse reshaping, and external switching. The transient phenomena that arise either from instabilities in the bistable systems themselves or from fluctuations in the number of nonlinear atoms or in the number of intracavity photons are also considered. The final chapter examines the characteristics and fundamental limitations of an ideal device, the prospect of improving devices by identifying giant nonlinearities, and the utilization of the full power of optics by parallel processing. This monograph is intended for new entrants and active workers in the field of optical bistability.