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In this Brief, Joe Jeffers uncovers the life and works of two-time Nobel Laureate Frederick Sanger. Following Sanger’s early life to retirement, Jeffers describes how this celebrated British biochemist became the first person to determine the amino acid sequence of a protein for which he was awarded the Nobel Prize in 1958. Highlighting Sanger’s remarkable career, Jeffers describes Sanger’s later change in research direction to investigate deoxyribonucleic acids (DNA), work for which Sanger also received the Nobel Prize jointly with Paul Berg and Walter Gilbert in 1980. Joe Jeffers conducted twelve interviews with Sanger over the period of 1999-2009 and he has also spoken to more than 40 of Sanger’s colleagues and family members. This brief provides a rigorous yet concise view of Sanger on a personal and scientific level and is suitable for biochemists, historians or the interested layperson.
Descendants of Frederick Miller
Aboard a long-range research vessel, in the vast reaches of the South Pacific, the cast and crew of the reality show Sealife believe they have found a ratings bonanza. For a director dying for drama, a distress call from Henders Island—a mere blip on any radar—might be just the ticket. Until the first scientist sets foot on Henders—and the ultimate test of survival begins. For when they reach the island’s shores, the scientists are utterly unprepared for what they find—creatures unlike any ever recorded in natural history. This is not a lost world frozen in time; this is Earth as it might have looked after evolving on a separate path for half a billion years—a fragment of a lost continent, with an ecosystem that could topple ours like a house of cards.
This volume provides an extensive translation of the notes and fragments that survived Kant's death in 1804. These include marginalia, lecture notes, and sketches and drafts for his published works. They are important as an indispensable resource for understanding Kant's intellectual development and published works, casting fresh light on Kant's conception of his own philosophical methods and his relations to his predecessors, as well as on central doctrines of his work such as the theory of space, time and categories, the refutations of scepticism and metaphysical dogmatism, the theory of the value of freedom and the possibility of free will, the conception of God, the theory of beauty, and much more.
Frederick the Great (1712–1786), King of Prussia, initiated the Seven Years' War in 1756; outfought the formidable French, Russian, and Austrian armies aligned against him; and established Prussia as a major power, thereby decisively influencing the next two centuries of European history. He was also a brilliant military thinker whose observations arose from extensive battlefield experience.This volume presents a balanced selection from Frederick's writings on strategy, tactics, and mobility; the problems of logistics and a two-front war; the combined use of infantry, cavalry, and artillery; the history of the Prussian army; the critical battles of the Seven Years' War; generalship as an art; and much more. A majority of this material is translated here for the first time in English and available nowhere else. The result is an invaluable glimpse into the inner thoughts of a military genius.
This work is concerned with text on Polycarp of Smyrna and his association with the apostle John. The Harris Fragments text raises questions about martyrdom and apostolicity, the earliest history of Chrisitians at Ephesus and Smyrna, and the legacies of Polycarp and John among early Christians.