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Draw upon the foundations necessary for finding and interpreting research evidence across all healthcare professions. Revised to reflect the most current changes in the field of clinical research in rehabilitation and medicine, you'll find a growing emphasis on evidence-based practice (EBP) as well as new vocabulary that is being integrated into research and practice across disciplines.
Foundations of Clinical Research: Applications to Practice, 3/e serves as a comprehensive reference for a variety of research situations. This edition reflects the contemporary focus on evidence-based practice in health care, and the essential concepts for understanding analysis and research design. Expanded topics include measures of diagnostic accuracy, statistical estimates of validity and reliability, systematic reviews and meta-analysis, search strategies and critical appraisal of literature for clinical decision making and development of research. Written for those in the health professions, including physical therapy, occupational therapy, speech therapy, nursing, and exercise physiology, this text will be useful to developing clinicians, practitioners, graduate students and researchers.
Foundations of Clinical Research: Applications to Practice, 3/e provides the foundations that are necessary for finding and interpreting research evidence across all healthcare professions. This book has been revised to reflect the most current changes in the field of clinical research in rehabilitation and medicine, including the growing emphasis on evidence-based practice (EBP) that has become central to all of health care and the new vocabulary that is being integrated into research and practice across disciplines. There is also a new chapter on systematic reviews and meta-analysis as well as expanded content related to clinical decision making, including likelihood ratios, pretest and posttest probabilities, minimally important change and number needed to treat.
Become a successful evidence-based practitioner. How do you evaluate the evidence? Is the information accurate, relevant and meaningful for clinical decision making? Did the design fit the research questions and was the analysis and interpretation of data appropriate? Here are all the materials you need to take your first steps as evidence-based practitioners…how to use the design, data and analysis of research as the foundation for effective clinical decision making. You’ll find support every step of the way as you progress from the foundations of clinical research and concepts of measurement through the processes of designing studies and analyzing data to writing their own research proposal.
This is the first comprehensive guide to the design of behavioral randomized clinical trials (RCT) for chronic diseases. It includes the scientific foundations for behavioral trial methods, problems that have been encountered in past behavioral trials, advances in design that have evolved, and promising trends and opportunities for the future. The value of this book lies in its potential to foster an ability to “speak the language of medicine” through the conduct of high-quality behavioral clinical trials that match the rigor commonly seen in double-blind drug trials. It is relevant for testing any treatment aimed at improving a behavioral, social, psychosocial, environmental, or policy-level risk factor for a chronic disease including, for example, obesity, sedentary behavior, adherence to treatment, psychosocial stress, food deserts, and fragmented care. Outcomes of interest are those that are of clinical significance in the treatment of chronic diseases, including standard risk factors such as cholesterol, blood pressure, and glucose, and clinical outcomes such as hospitalizations, functional limitations, excess morbidity, quality of life, and mortality. This link between behavior and chronic disease requires innovative clinical trial methods not only from the behavioral sciences but also from medicine, epidemiology, and biostatistics. This integration does not exist in any current book, or in any training program, in either the behavioral sciences or medicine.
This classic reference, now updated with the newest applications and results, addresses the fundamentals of such trials based on sound scientific methodology, statistical principles, and years of accumulated experience by the three authors.
Scientific Foundations of Clinical Assessment is a user-friendly overview of the most important principles and concepts of clinical assessment. It provides readers with a science-based framework for interpreting assessment research and making good assessment decisions, such as selecting the best instruments and measures and interpreting the obtained assessment data. Written in a direct and highly readable fashion, with plenty of clinical examples that illustrate the relevance of psychometric principles and assessment research, this text is one every professional and graduate student needs to read. Numerous elements are used consistently throughout the book to facilitate understanding and retention, such as: • text boxes that provide extended presentations of the application of principles and research • end-of-chapter summaries that review key issues covered, and • additional recommended sources for each chapter. A detailed glossary that defines key measurement and assessment concepts is also included, making this book an invaluable reference and supplementary text for anyone who does clinical assessment in the health and mental health domains.
This book serves as a comprehensive reference for a variety of research situations. This edition reflects the popular approaches to analysis and design, and addresses the focus of health-care related research through the 1990s and into the 21st century. Expanded or added topics include outcomes research and the disablement model, validity and diagnostic screening, meta-analysis, scales used in survey and outcomes research, logistic regression, measures of reliability, and data management to prepare for computer analysis. For those in the health professions, including physical therapy, occupational therapy, speech therapy, nursing, and exercise physiology.
Advances in medical, biomedical and health services research have reduced the level of uncertainty in clinical practice. Clinical practice guidelines (CPGs) complement this progress by establishing standards of care backed by strong scientific evidence. CPGs are statements that include recommendations intended to optimize patient care. These statements are informed by a systematic review of evidence and an assessment of the benefits and costs of alternative care options. Clinical Practice Guidelines We Can Trust examines the current state of clinical practice guidelines and how they can be improved to enhance healthcare quality and patient outcomes. Clinical practice guidelines now are ubiquitous in our healthcare system. The Guidelines International Network (GIN) database currently lists more than 3,700 guidelines from 39 countries. Developing guidelines presents a number of challenges including lack of transparent methodological practices, difficulty reconciling conflicting guidelines, and conflicts of interest. Clinical Practice Guidelines We Can Trust explores questions surrounding the quality of CPG development processes and the establishment of standards. It proposes eight standards for developing trustworthy clinical practice guidelines emphasizing transparency; management of conflict of interest ; systematic review-guideline development intersection; establishing evidence foundations for and rating strength of guideline recommendations; articulation of recommendations; external review; and updating. Clinical Practice Guidelines We Can Trust shows how clinical practice guidelines can enhance clinician and patient decision-making by translating complex scientific research findings into recommendations for clinical practice that are relevant to the individual patient encounter, instead of implementing a one size fits all approach to patient care. This book contains information directly related to the work of the Agency for Healthcare Research and Quality (AHRQ), as well as various Congressional staff and policymakers. It is a vital resource for medical specialty societies, disease advocacy groups, health professionals, private and international organizations that develop or use clinical practice guidelines, consumers, clinicians, and payers.
The purpose of the book is to provide an overview of clinical research (types), activities, and areas where informatics and IT could fit into various activities and business practices. This book will introduce and apply informatics concepts only as they have particular relevance to clinical research settings.