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A comprehensive, multidisciplinary review, Neural Plasticity and Memory: From Genes to Brain Imaging provides an in-depth, up-to-date analysis of the study of the neurobiology of memory. Leading specialists share their scientific experience in the field, covering a wide range of topics where molecular, genetic, behavioral, and brain imaging techniq
“Fascinating and useful . . . The distinguished memory researcher Scott A. Small explains why forgetfulness is not only normal but also beneficial.”—Walter Isaacson, bestselling author of The Code Breaker and Leonardo da Vinci Who wouldn’t want a better memory? Dr. Scott Small has dedicated his career to understanding why memory forsakes us. As director of the Alzheimer’s Disease Research Center at Columbia University, he focuses largely on patients who experience pathological forgetting, and it is in contrast to their suffering that normal forgetting, which we experience every day, appears in sharp relief. Until recently, most everyone—memory scientists included—believed that forgetting served no purpose. But new research in psychology, neurobiology, medicine, and computer science tells a different story. Forgetting is not a failure of our minds. It’s not even a benign glitch. It is, in fact, good for us—and, alongside memory, it is a required function for our minds to work best. Forgetting benefits our cognitive and creative abilities, emotional well-being, and even our personal and societal health. As frustrating as a typical lapse can be, it’s precisely what opens up our minds to making better decisions, experiencing joy and relationships, and flourishing artistically. From studies of bonobos in the wild to visits with the iconic painter Jasper Johns and the renowned decision-making expert Daniel Kahneman, Small looks across disciplines to put new scientific findings into illuminating context while also revealing groundbreaking developments about Alzheimer’s disease. The next time you forget where you left your keys, remember that a little forgetting does a lot of good.
A New York Times Notable Book: A psychologist’s “gripping and thought-provoking” look at how and why our brains sometimes fail us (Steven Pinker, author of How the Mind Works). In this intriguing study, Harvard psychologist Daniel L. Schacter explores the memory miscues that occur in everyday life, placing them into seven categories: absent-mindedness, transience, blocking, misattribution, suggestibility, bias, and persistence. Illustrating these concepts with vivid examples—case studies, literary excerpts, experimental evidence, and accounts of highly visible news events such as the O. J. Simpson verdict, Bill Clinton’s grand jury testimony, and the search for the Oklahoma City bomber—he also delves into striking new scientific research, giving us a glimpse of the fascinating neurology of memory and offering “insight into common malfunctions of the mind” (USA Today). “Though memory failure can amount to little more than a mild annoyance, the consequences of misattribution in eyewitness testimony can be devastating, as can the consequences of suggestibility among pre-school children and among adults with ‘false memory syndrome’ . . . Drawing upon recent neuroimaging research that allows a glimpse of the brain as it learns and remembers, Schacter guides his readers on a fascinating journey of the human mind.” —Library Journal “Clear, entertaining and provocative . . . Encourages a new appreciation of the complexity and fragility of memory.” —The Seattle Times “Should be required reading for police, lawyers, psychologists, and anyone else who wants to understand how memory can go terribly wrong.” —The Atlanta Journal-Constitution “A fascinating journey through paths of memory, its open avenues and blind alleys . . . Lucid, engaging, and enjoyable.” —Jerome Groopman, MD “Compelling in its science and its probing examination of everyday life, The Seven Sins of Memory is also a delightful book, lively and clear.” —Chicago Tribune Winner of the William James Book Award
THE INTERNATIONAL BESTSELLER 'Truly fascinating.' Steve Wright, BBC Radio 2 - Have you ever forgotten the name of someone you’ve met dozens of times? - Or discovered that your memory of an important event was completely different from everyone else’s? - Or vividly recalled being in a particular place at a particular time, only to discover later that you couldn’t possibly have been? We rely on our memories every day of our lives. They make us who we are. And yet the truth is, they are far from being the accurate record of the past we like to think they are. In The Memory Illusion, forensic psychologist and memory expert Dr Julia Shaw draws on the latest research to show why our memories so often play tricks on us – and how, if we understand their fallibility, we can actually improve their accuracy. The result is an exploration of our minds that both fascinating and unnerving, and that will make you question how much you can ever truly know about yourself. Think you have a good memory? Think again. 'A spryly paced, fun, sometimes frightening exploration of how we remember – and why everyone remembers things that never truly happened.' Pacific Standard
The brain ... There is no other part of the human anatomy that is so intriguing. How does it develop and function and why does it sometimes, tragically, degenerate? The answers are complex. In Discovering the Brain, science writer Sandra Ackerman cuts through the complexity to bring this vital topic to the public. The 1990s were declared the "Decade of the Brain" by former President Bush, and the neuroscience community responded with a host of new investigations and conferences. Discovering the Brain is based on the Institute of Medicine conference, Decade of the Brain: Frontiers in Neuroscience and Brain Research. Discovering the Brain is a "field guide" to the brainâ€"an easy-to-read discussion of the brain's physical structure and where functions such as language and music appreciation lie. Ackerman examines: How electrical and chemical signals are conveyed in the brain. The mechanisms by which we see, hear, think, and pay attentionâ€"and how a "gut feeling" actually originates in the brain. Learning and memory retention, including parallels to computer memory and what they might tell us about our own mental capacity. Development of the brain throughout the life span, with a look at the aging brain. Ackerman provides an enlightening chapter on the connection between the brain's physical condition and various mental disorders and notes what progress can realistically be made toward the prevention and treatment of stroke and other ailments. Finally, she explores the potential for major advances during the "Decade of the Brain," with a look at medical imaging techniquesâ€"what various technologies can and cannot tell usâ€"and how the public and private sectors can contribute to continued advances in neuroscience. This highly readable volume will provide the public and policymakersâ€"and many scientists as wellâ€"with a helpful guide to understanding the many discoveries that are sure to be announced throughout the "Decade of the Brain."
A memoir from the Emmy-winning Saturday Night Live writer that is “funny, spiky, and twistedly entertaining” (Entertainment Weekly). 39 Years of Short-Term Memory Loss is a seriously funny and irreverent memoir that gives an insider’s view of the birth and rise of Saturday Night Live, and features laugh-out-loud stories about some of its greatest personalities—Al Franken, Lorne Michaels, Dan Aykroyd, John Belushi, Bill Murray, Michael O’Donoghue, and Chris Farley. Tom Davis’s voice is rich with irony and understatement as he tells tales of discovery, triumph, and loss with relentless humor. His memoir describes not only his experiences on the set of SNL but also his suburban childhood, his high school escapades in the sixties, his discovery of sex, and how he reveled in the hippie culture—and psychoactive drugs—from San Francisco to Kathmandu to Burning Man over the last four decades. Hysterical, lucid, and wise, 39 Years of Short-Term Memory Loss is an unforgettable romp in an era of sex, drugs, and comedy. “Though it features some lurid and hysterical SNL stories, Davis’s memoir is less a backstage expose than a winning coming-of-age story featuring a funny Midwestern kid following his unlikely dream to the top.” —Publishers Weekly, starred review
Quiet towns keep big secrets. Private investigator Jessica Shaw is leading a quiet life in a Californian desert community, where she spends her days working low-level cases. But when a former resident asks Jessica to help her sister, Rue Hunter--a convicted murderer whose execution is days away--Jessica can't resist the offer. Rue doesn't remember what happened the night two high school students were killed thirty years ago, but everybody in town is certain she's guilty. As Jessica looks for answers, she finds that local rumors point one way and evidence points another. And nobody wants to face the truth. Meanwhile, Jessica can't shake the feeling that someone is stalking her--now more than ever, she knows she can't trust anyone. As Jessica digs deeper, she encounters local secrets in unlikely places--including the police department itself. But the clock is ticking, and Jessica must find the truth fast--or Rue's bad memory may be the death of them both.
As you age, you may find yourself worrying about your memory. Where did I put those car keys? What time was my appointment? What was her name again? With more than 41 million Americans over the age of 65 in the United States, the question becomes how much (or, perhaps, what type) of memory loss is to be expected as one gets older and what should trigger a visit to the doctor. Seven Steps to Managing Your Memory addresses these key concerns and more, such as... · What are the signs that suggest your memory problems are more than just part of normal aging? · Is it normal to have concerns about your memory? · What are the markers of mild cognitive impairment, dementia, Alzheimer's, and other neurodegenerative diseases? · How should you convey your memory concerns to your doctor? · What can your doctor do to evaluate your memory? · Which healthcare professional(s) should you see? · What medicines, alternative therapies, diets, and exercises are available to improve your memory? · Can crossword puzzles, computer brain-training games, memory aids, and strategies help strengthen your memory? · What other resources are available when dealing with memory loss? Seven Steps to Managing Your Memory is written in an easy-to-read yet comprehensive style, featuring clinical vignettes and character-based stories that provide real-life examples of how to successfully manage age-related memory loss.
Supervised sequence labelling is a vital area of machine learning, encompassing tasks such as speech, handwriting and gesture recognition, protein secondary structure prediction and part-of-speech tagging. Recurrent neural networks are powerful sequence learning tools—robust to input noise and distortion, able to exploit long-range contextual information—that would seem ideally suited to such problems. However their role in large-scale sequence labelling systems has so far been auxiliary. The goal of this book is a complete framework for classifying and transcribing sequential data with recurrent neural networks only. Three main innovations are introduced in order to realise this goal. Firstly, the connectionist temporal classification output layer allows the framework to be trained with unsegmented target sequences, such as phoneme-level speech transcriptions; this is in contrast to previous connectionist approaches, which were dependent on error-prone prior segmentation. Secondly, multidimensional recurrent neural networks extend the framework in a natural way to data with more than one spatio-temporal dimension, such as images and videos. Thirdly, the use of hierarchical subsampling makes it feasible to apply the framework to very large or high resolution sequences, such as raw audio or video. Experimental validation is provided by state-of-the-art results in speech and handwriting recognition.
Social isolation and loneliness are serious yet underappreciated public health risks that affect a significant portion of the older adult population. Approximately one-quarter of community-dwelling Americans aged 65 and older are considered to be socially isolated, and a significant proportion of adults in the United States report feeling lonely. People who are 50 years of age or older are more likely to experience many of the risk factors that can cause or exacerbate social isolation or loneliness, such as living alone, the loss of family or friends, chronic illness, and sensory impairments. Over a life course, social isolation and loneliness may be episodic or chronic, depending upon an individual's circumstances and perceptions. A substantial body of evidence demonstrates that social isolation presents a major risk for premature mortality, comparable to other risk factors such as high blood pressure, smoking, or obesity. As older adults are particularly high-volume and high-frequency users of the health care system, there is an opportunity for health care professionals to identify, prevent, and mitigate the adverse health impacts of social isolation and loneliness in older adults. Social Isolation and Loneliness in Older Adults summarizes the evidence base and explores how social isolation and loneliness affect health and quality of life in adults aged 50 and older, particularly among low income, underserved, and vulnerable populations. This report makes recommendations specifically for clinical settings of health care to identify those who suffer the resultant negative health impacts of social isolation and loneliness and target interventions to improve their social conditions. Social Isolation and Loneliness in Older Adults considers clinical tools and methodologies, better education and training for the health care workforce, and dissemination and implementation that will be important for translating research into practice, especially as the evidence base for effective interventions continues to flourish.