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Foamy viruses, also known as spumaviruses, are complex retroviruses which make up a subfamily of Retroviridae family. This class of viruses can naturally infect a variety of animals including non-human primates (NHPs). Spumaretroviruses are unique and unconventional with respect to many aspects of molecular biology such as assembly and release of enveloped viral particles. There are three major proteins that are encoded within the retroviral genome, namely, group antigens (Gag), envelope protein (Env), and reverse transcriptase (Pol). Both Gag and Env as components of the minimal assembly and the release machinery display substantial variations in their molecular structures and functions compared to other retroviruses. Some of the distinct features of spumaretroviruses, which are not found in other retroviruses, are genome coding strategy, sequence features, mode and timing of Gag polyprotein processing, and packaging and activation of the Pol gene-associated enzymatic functions. This book provides a comprehensive overview of all aspects of the microbiology and immunology of foamy viruses. Researchers and students in the field of medical microbiology will be greatly assisted by it.
The aberrant replication pathway of foamy viruses distinguishes them from all other retroviruses. Many details have been accumulated over the past ten or so years. Most of the findings on foamy viruses were obtained by research on a single virus isolate previously called "human foamy virus", which appeared to be the first to be investigated on a molecular level. However, to the editor's knowledge, genuine human foamy viruses do not exist, but several trans-species transmissions of different simian foamy viruses from monkeys and apes to human hosts.
Fundamentals of Medical Microbiology, 2nd. Edit. encapsulates the updated essential principles and facts of Medical Bacteriology, Immunology, Virology, Mycology and Parasitology. It provides an easy way to study rapidly, and comprehensively the most recent as well as concise information for the above-mentioned areas of Medical Microbiology & Immunology. Another key feature of this book is that it focuses on what allied health students, such as college, medical, public health students really need to know to perform well in their medical microbiology & Immunology courses, the national boards (USMLE, Step 1) related local or state examinations, and for clinical rotations. • A comprehensive description of germane concepts and facts of medical microbiology and immunology • High yield content that reinforces relevant principles and essential course information • Attempts to answer what a medical student needs to know to pass a test in medical microbiology and immunology • Provides a current, quick review of relevant information of medical microbiology and immunology • Subject by subject exposure to fundamental information where you need it most
The first book to specifically cover the molecular biology of retroviruses - of immense importance since the high profile of HIV. International contributors provide detailed reviews of the latest knowledge. An excellent text for both medical and non-medical researchers, it also serves as an illuminating introduction for scientists active in other areas.
Now in four convenient volumes, Field’s Virology remains the most authoritative reference in this fast-changing field, providing definitive coverage of virology, including virus biology as well as replication and medical aspects of specific virus families.
Get the most from your study time, and experience a realistic USMLE simulation with Rapid Review Microbiology and Immunology, 3rd Edition, by Drs. Ken S. Rosenthal and Michael J. Tan. This new reference in the highly rated Rapid Review Series is formatted as a bulleted outline with photographs, tables and figures that address all the microbiology and immunology information you need to know for the USMLE. And with Student Consult functionality, you can become familiar with the look and feel of the actual exam by taking a timed or a practice test online that includes 400 USMLE-style questions. Access all the information you need to know quickly and easily with a user-friendly, two-color outline format that includes High-Yield Margin Notes. Take a timed or a practice test online with more than 400 USMLE-style questions and full rationales for why every possible answer is right or wrong. Review the most current information with completely updated chapters, images, and questions, including a new chapter on Laboratory Tests for Diagnosis. Profit from the guidance of series editor, Dr. Edward Goljan, a well-known author of medical study references, who is personally involved in content review. Study and take notes more easily with the new, larger page size. Practice with a new testing platform on USMLE Consult that gives you a realistic review experience and fully prepares you for the exam. Review your understanding of how to interpret lab results in a new chapter on Laboratory Tests for Diagnosis.
The most concise, comprehensive, and up-to-date medical microbiology & immunology review! Gives students the high-yield information they need to prepare for the USMLE Step 1 and course exams. Completely updated throughout, the new edition covers developments in HIV, hepatitis, smallpox, SARS, and more. Features case discussions, USMLE-style questions, and a USMLE-style practice exam.
Cytopathology of Infectious Diseases is the first book of its kind to focus entirely on the cytopathology of infectious diseases. It contains all of the pertinent information about the cytology of infectious diseases and microorganisms and will serve as an ideal handy reference. This unique volume covers the cytomorphology of various microorganisms and the host reactions they elicit, and also incorporates an update on advances in the field. Newly recognized infections such as the recent discovery of the Merkel Cell Polyomavirus (MCV) are included, as well as the utility of new immunostains (e.g. CM2B4 for MCV) and the role of molecular techniques that assist in the identification, classification and even quantification of microorganisms. Each chapter is succinctly written and concisely referenced with key published articles and resources. The volume includes practical pointers, useful diagnostic criteria, differential diagnoses and potential pitfalls. Many color images of high resolution that illustrate microorganisms (e.g. branching hyphae) and host reactions (e.g. viral cytopathic effect) are included throughout. Relevant tables with diagrams that provide quick reference guides are incorporated. Cytopathology of Infectious Diseases will serve as a valuable reference tool for cytopathologists, anatomical/clinical pathologists, cytotechnologists, pathology residents and cytopathology fellows.
This comprehensive account of the human herpesviruses provides an encyclopedic overview of their basic virology and clinical manifestations. This group of viruses includes human simplex type 1 and 2, Epstein–Barr virus, Kaposi's Sarcoma-associated herpesvirus, cytomegalovirus, HHV6A, 6B and 7, and varicella-zoster virus. The viral diseases and cancers they cause are significant and often recurrent. Their prevalence in the developed world accounts for a major burden of disease, and as a result there is a great deal of research into the pathophysiology of infection and immunobiology. Another important area covered within this volume concerns antiviral therapy and the development of vaccines. All these aspects are covered in depth, both scientifically and in terms of clinical guidelines for patient care. The text is illustrated generously throughout and is fully referenced to the latest research and developments.