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Fine Needle Aspiration Cytology (FNAC) is a popular and effective technique for quick tissue diagnosis. Beginning with an introduction to the technique of FNAC, this book provides a concise, logical and systemic approach to the diagnosis of lesions that may occur in different parts of the body. The author discusses the various diagnostic difficulties and problems with the interpretation of FNAC. Emphasis is placed on cytomorphology (the structure of body cells), but immunocytochemistry (a microscopic method that uses antibodies to localise proteins in tissue sections and cell cutures), and other ancillary techniques, are also discussed. The text is accompanied by numerous high quality coloured figures of individual lesions with detailed descriptions.
Fine-needle aspiration cytology (FNAC) is a diagnostic procedure used to investigate superficial lumps or masses. This procedure is widely used in the diagnosis of cancer and inflammatory conditions. Fine Needle Aspiration Cytology: Interpretation and Diagnostic Difficulties is organised into 21 chapters covering the full spectrum of fine needle aspiration cytology, organ by organ, from head, neck and orbital to skin, bone and the central nervous system. This book provides comprehensive, current information on the principles and techniques of fine needle aspiration cytology, enhanced by 829 full colour images and illustrations, tables and message boxes. Illustrations of neoplastic lesions are accompanied by discussion on the use of fine needle aspiration technique in the investigation of nodules and masses suspected to be of neoplastic origin. This second edition has 8 new chapters, providing updated information on the use of FNAC for pancreas, gall bladder, soft tissue lesions, and skin and bone with a large number of new microphotographs, making Fine Needle Aspiration Cytology: Interpretation and Diagnostic Difficulties one of the most current guides to this technique. Key Features Second edition features 8 new chapters 829 full colour images and illustrations First edition published 2002
This book covers all of the diagnostic areas where FNAC is used today. This includes palpable lesions and lesions sampled using various radiological methods, and correlations with ancillary examinations detailed on an entity-by-entity basis. As well as being a complete atlas of the facts and findings important to FNAC, this atlas is a guide to diagnostic methods that optimize health care. The interaction of the cytologist or cytopathologist with other specialists (radiologists, oncologists and surgeons) involved in the diagnosis and treatment of patients with suspicious mass lesions is emphasized and illustrated throughout. With contributions from experts in the field internationally and abundant colour images Atlas of Fine Needle Aspiration Cytology provides a comprehensive and up-to-date guide to FNAC for pathologists, cytopathologists, radiologists, oncologists, surgeons and others involved in the diagnosis and treatment of patients with suspicious mass lesions.
Histopathologists all over the world have to report cytopathology during the course of their work and it is then that they find themselves facing diagnostic dilemmas. This practical, well-illustrated book, explicitly dedicated to this readership will serve their needs and meets their requirements in daily practice.
This atlas is the offspring of the “The National Cancer Institute (NCI) Thyroid Fine Needle Aspiration (FNA) State of the Science Conference,” hosted by the NCI and organized by Dr. Andrea Abati. Preparations for the conference began 18 months earlier with the designation of a steering committee and the establishment of a dedicated, p- manent web site. The meeting took place on October 22 and 23, 2007 in Bethesda, Maryland and was co-moderated by Susan J. Mandel and Edmund S. Cibas. The discussions and conclusions regarding terminology and morphologic criteria 1, 2 from the meeting were summarized in publications by Baloch et al. and form the framework for this atlas. The atlas is organized by the general categories of “Nondiagnostic,” “Benign,” “Follicular Neoplasm/Suspicious for a Follicular Neoplasm”, “Suspicious for Malignancy,” and “Malignant,” and it includes the defi- tions and morphologic criteria of these categories as set forth by Baloch et al. The majority of the conference participants also agreed on a category of “undetermined significance,” which is incorporated in this atlas (Chap. 4). It is critical that the cytopathologist communicate thyroid FNA interpretations to the referring physician in terms that are succinct, unambiguous, and helpful clinically. We recognize that the terminology used here is a flexible framework that can be modified by individual laboratories to meet the needs of their providers and the patients they serve.
This text describes a system of reporting breast fine needle aspiration biopsy that uses five clearly defined categories, each described by a specific term and each with a specific risk of malignancy. The five categories are insufficient/inadequate, benign, atypical, suspicious of malignancy and malignant. Each category has a risk of malignancy and is linked to management recommendations, which include several options because it is recognized that diagnostic infrastructure, such as the availability of core needle biopsy and ultrasound guidance, vary between developed and low and middle income countries. This text includes key diagnostic cytological criteria for each of the many lesions and tumors found in the breast. The cytopathology of specific lesions is illustrated with high quality photomicrographs with clear figure descriptions. Chapters also discuss current and potential future ancillary tests, liquid based cytology, nipple cytology and management. An additional chapter provides an overview of an approach to the diagnosis of direct smears of breast fine needle aspiration biopsies. The International Academy of Cytology Yokohama System for Reporting Breast Fine Needle Aspiration Biopsy Cytopathology provides a clear logical approach to the diagnosis and categorization of breast lesions by FNAB cytology, and aims to facilitate communication with breast clinicians, further research into breast cytopathology and related molecular pathology, and improve patient care.
This book provides a detailed update on all aspects of fine-needle aspiration cytology of breast lesions. It will serve readers as an up-to-date reference and atlas on both new entities in breast pathology, including borderline lesions such as flat epithelial atypia, and the classic benign and malignant lesions. Throughout, emphasis is placed on the characteristic diagnostic features as well as the common pitfalls faced by cytologists. As cytologic features can be highly variable, corresponding cytology and histology images are displayed together, enabling readers to gain a good understanding of the morphologic features of various lesions. Core-needle biopsy and fine-needle aspiration cytology are compared in depth, with attention to their relative strengths and weaknesses and indications. In addition, the impact of molecular classification of breast cancers on cytologic diagnosis is explored, and the use of molecular techniques in diagnostic cytology is discussed.
? Over 1,350 illustrations in 350 innovative composite figures designed to teach general pathologists the cytologic approach and cytologists the histologic basis for cytologic criteria? CD-ROM containing high resolution composite images that can be enlarged to the size of computer screen and detailed legends with clinical presentation, cytologic clues with different stains from low to high magnification as well as the mistakes made and lessons learned? Pathologic entities are arranged in the current classifications used by surgical pathologists so that they can translate their experience in histopathology to cytopathology? New classifications of tumors based on advances in cytogenetic and molecular evidence and all new illustrated cases from G C H Yang's collection? A new chapter on gynecologic tumors has been added. The chapter on malignant lymphoma has been completely rewritten to incorporate current WHO classifications. New tumors discovered in the past 16 years and new classifications of adrenal, kidney, liver and pancreatic tumors have been addedThe objective of this book is to share authors' combined 30 years' experience in the fine-needle aspiration biopsy diagnosis of organs beneath the diaphragm with general pathologists. Starting from the basics, this book progresses to in-depth cytomorphologic analysis with histologic and immunohistochemical confirmation of specific entities. Cytohistological correlation is emphasized by using composite images from either resected tumor or the cell block whenever possible. In addition, ultrastructural basis of cytological features is emphasized. Both cytology and electron microscopy classify tumors by meticulously analyzing the cytoplasmic features and cell junctions of scanty sample. Every histopathology entity should have a counterpart in cytopathology, since both derive from the same entity undergoing the same pathological process. The difference is in the artifacts; thus an attempt was made to explain the artifacts of aspiration cytology so that histopathologists may understand the cytologic approach and learn to interpret aspiration cytology with confidence.
This book introduces basic ROSE techniques and resources required to set up ROSE service. It reviews the cytomorphologic features that are recognizable during ROSE, including those important for sample adequacy, specimen triage, preliminary interpretation, and potential diagnostic pitfalls. Economic and regulatory aspects are discussed as well as the pros and cons of telecytology. The book is formatted for clinical settings, simulating the ROSE process that occurs in the ultrasound room, CT room, bronchoscopy suite, and endoscopy suite. Each chapter focuses on the cytomorphologic clues and pitfalls of the entities specific to that clinical setting. Rapid On-Site Evaluation: A Practical Guide will be a valuable resource for pathologists, cytotechnologists, physicians who perform biopsies and/or ROSE evaluation, and trainees for utilizing ROSE and improving diagnostic performance of biopsies.
The Second Edition of The Milan System for Reporting Salivary Gland Cytopathology, like the First Edition, represents a collaborative effort by a multidisciplinary group of cytopathologists, surgical pathologists, molecular pathologists, radiologists, and head and neck surgeons. This international group shares the goal of creating a practical and uniform reporting system for salivary gland fine needle aspiration (FNA). This book is organized into six general diagnostic categories: “Non-Diagnostic,” “Non-Neoplastic,” “Atypia of Undetermined Significance (AUS),” “Neoplasm: Benign,” “Neoplasm: Salivary Gland Neoplasm of Uncertain Malignant Potential (SUMP),” “Suspicious for Malignancy,” and “Malignant.” It includes definitions, morphologic criteria, and explanations for each of the diagnostic categories. Specific chapters are dedicated to the application of the latest available ancillary studies, radiologic features of salivary gland lesions, clinical management, and histological considerations including updates from the most recent 5th Edition WHO blue book. The Milan System for Reporting Salivary Gland Cytopathology 2nd Edition represents an essential step towards increasing the overall effectiveness of salivary gland FNA and fostering better communication between clinicians and between institutions to improve overall patient care.