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This book covers all of the diagnostic areas where FNAC is used today. This includes palpable lesions and lesions sampled using various radiological methods, and correlations with ancillary examinations detailed on an entity-by-entity basis. As well as being a complete atlas of the facts and findings important to FNAC, this atlas is a guide to diagnostic methods that optimize health care. The interaction of the cytologist or cytopathologist with other specialists (radiologists, oncologists and surgeons) involved in the diagnosis and treatment of patients with suspicious mass lesions is emphasized and illustrated throughout. With contributions from experts in the field internationally and abundant colour images Atlas of Fine Needle Aspiration Cytology provides a comprehensive and up-to-date guide to FNAC for pathologists, cytopathologists, radiologists, oncologists, surgeons and others involved in the diagnosis and treatment of patients with suspicious mass lesions.
Orell & Sterrett's Fine Needle Aspiration Cytology 5e provides you with a logical and systematic approach to the acquisition, interpretation and diagnosis of FNA biopsy samples. It is an ideal resource for all those requiring an authoritative and systematic review of the cytological findings in those malignant and benign lesions likely to be the target of FNA. The book is lavishly illustrated with high quality colour images that demonstrate the cytological features as well as their relevant immunohistochemical and molecular findings. Organized into anatomical regions, each chapter is consistently organized into two parts: the first deals with clinical and technical aspects followed by a systematic presentation of cytological findings. This is your perfect practical bench resource for daily reference in the laboratory. Provides practical tips and advice on how to avoid pitfalls and ensure accurate diagnoses. Over 1,200 colour illustrations capture each entity's cellular, morphological and immunohistochemical appearance. Chapters have been up-dated and revised and a brand new one on cytological findings in infectious diseases added. Both MGG and Pap smears illustrated in parallel as well as the corresponding histology to help provide side-by-side analysis. Access the full text online and download images via Expert Consult.
​ The Invasive Cytopathologist: Ultrasound Guided Fine-Needle Aspiration of Superficial Masses provides a comprehensive review of the cytology of superficial neoplastic and non-neoplastic disease processes obtained by percutaneous ultrasound guidance, particularly of thyroid, parathyroid, lymph nodes, salivary glands, breast, and soft tissue with ultrasound image and histopathology correlation. This book emphasizes on the basic ultrasound characteristics of thyroid nodules, the cytology of common and uncommon neoplastic and non-neoplastic processes according to the Bethesda System for Reporting Thyroid Cytopathology, and provides a technical guide for how to perform ultrasound-guided FNA of thyroid nodules to obtain adequate material for diagnosis. The volume also briefly reviews the molecular aspects of thyroid neoplasia useful for targeted therapy. The Invasive Cytopathologist: Ultrasound Guided Fine-Needle Aspiration of Superficial Masses is a useful guide for ultrasound evaluation, cytological interpretation and differential diagnostic considerations of superficial masses, and is a valuable source of information for cytopathologists, cytopathology fellows, cytotechnology students and upper level pathology residents. Endocrinologists, thyroidologists, head and neck specialists, and any professional with interest in ultrasound and fine needle aspiration cytology of superfial masses will benefit from this book.
This text describes a system of reporting breast fine needle aspiration biopsy that uses five clearly defined categories, each described by a specific term and each with a specific risk of malignancy. The five categories are insufficient/inadequate, benign, atypical, suspicious of malignancy and malignant. Each category has a risk of malignancy and is linked to management recommendations, which include several options because it is recognized that diagnostic infrastructure, such as the availability of core needle biopsy and ultrasound guidance, vary between developed and low and middle income countries. This text includes key diagnostic cytological criteria for each of the many lesions and tumors found in the breast. The cytopathology of specific lesions is illustrated with high quality photomicrographs with clear figure descriptions. Chapters also discuss current and potential future ancillary tests, liquid based cytology, nipple cytology and management. An additional chapter provides an overview of an approach to the diagnosis of direct smears of breast fine needle aspiration biopsies. The International Academy of Cytology Yokohama System for Reporting Breast Fine Needle Aspiration Biopsy Cytopathology provides a clear logical approach to the diagnosis and categorization of breast lesions by FNAB cytology, and aims to facilitate communication with breast clinicians, further research into breast cytopathology and related molecular pathology, and improve patient care.
A comprehensive color manual Fine-needle aspiration (FNA) became important for the cytology of the enlarged lymph node in the 1950s and 1960s and was accepted in the diagnosis of various types of lymphadenitis and metastatic disease. The diagnosis of lymphoma by FNA cytology, however, remained controversial for many years, as FNA smears did not allow the evaluation of growth pattern. Only later with the introduction of immunocytochemistry on FNA material it became possible to conclusively diagnose the majority of lymphomas with an accuracy comparable to that of histopathology. Other ancillary techniques such as FISH and PCR can now also be applied successfully to FNA material. These facts together with the excellent clinical performance of FNA sampling should increase the spread of the technique. This comprehensive manual presents the cytomorphologic and immunocytochemical characteristics of both non-Hodgkin and Hodgkin lymphomas. It discusses the technical, methodological aspects of lymphoma diagnosis and describes the cytologic features of reactive lymphoid lesions and the major types of neoplastic lymphoid lesions, based on the most recent (2001) WHO lymphoma classification. Key cytologic and immunologic features are listed to facilitate a conclusive diagnosis of the different lesions. This publication will be of immense value to clinicians such as cytopathologists, pathologists, oncologists, and hematologists involved in the clinical work-up and management of patients with lymph node lesions.
This volume in the Essentials in Cytopathology book series will focus on the cytopathology of lymph nodes. It will address the topic of fine needle aspiration of lymph nodes and fulfill the need for an easy-to-use and authoritative synopsis of lymph node cytopathology. The book with adopt an algorithmic diagnostic approach, starting from the cytomorphologic pattern of the lymph node aspirate. The focus will be on the appropriate and effective use of ancillary studies (immunohistochemistry, flow cytometry, fluorescence in situ hybridization and molecular techniques) and integration of their results into the final diagnosis. The book will present the cytopathologic features and differential diagnoses for the major cytologic patterns in lymph node fine needle aspiration. The entities typically falling within each of these patterns will be discussed with illustration of the spectrum of cytologic features, differential diagnoses and pitfalls. The book will cover the full spectrum of benign and malignant primary conditions of the lymph nodes, with emphasis on common disorders. Discussion of metastatic conditions will be restricted to those that are relevant to the differential diagnosis of primary lymphoid disorders. This book is designed as an easy to use resource that fits into the lab coat pocket, ideal for portability and quick reference. It is heavily illustrated and contains useful algorithms that guide the reader through the differential diagnosis of common and uncommon entities encountered in lymph node aspirates. The accompanying text follows an easy to use pattern-based outline. A useful resource for every pathologist, cytopathologist, fellow and trainee.
This book provides a detailed update on all aspects of fine-needle aspiration cytology of breast lesions. It will serve readers as an up-to-date reference and atlas on both new entities in breast pathology, including borderline lesions such as flat epithelial atypia, and the classic benign and malignant lesions. Throughout, emphasis is placed on the characteristic diagnostic features as well as the common pitfalls faced by cytologists. As cytologic features can be highly variable, corresponding cytology and histology images are displayed together, enabling readers to gain a good understanding of the morphologic features of various lesions. Core-needle biopsy and fine-needle aspiration cytology are compared in depth, with attention to their relative strengths and weaknesses and indications. In addition, the impact of molecular classification of breast cancers on cytologic diagnosis is explored, and the use of molecular techniques in diagnostic cytology is discussed.
? Over 1,350 illustrations in 350 innovative composite figures designed to teach general pathologists the cytologic approach and cytologists the histologic basis for cytologic criteria? CD-ROM containing high resolution composite images that can be enlarged to the size of computer screen and detailed legends with clinical presentation, cytologic clues with different stains from low to high magnification as well as the mistakes made and lessons learned? Pathologic entities are arranged in the current classifications used by surgical pathologists so that they can translate their experience in histopathology to cytopathology? New classifications of tumors based on advances in cytogenetic and molecular evidence and all new illustrated cases from G C H Yang's collection? A new chapter on gynecologic tumors has been added. The chapter on malignant lymphoma has been completely rewritten to incorporate current WHO classifications. New tumors discovered in the past 16 years and new classifications of adrenal, kidney, liver and pancreatic tumors have been addedThe objective of this book is to share authors' combined 30 years' experience in the fine-needle aspiration biopsy diagnosis of organs beneath the diaphragm with general pathologists. Starting from the basics, this book progresses to in-depth cytomorphologic analysis with histologic and immunohistochemical confirmation of specific entities. Cytohistological correlation is emphasized by using composite images from either resected tumor or the cell block whenever possible. In addition, ultrastructural basis of cytological features is emphasized. Both cytology and electron microscopy classify tumors by meticulously analyzing the cytoplasmic features and cell junctions of scanty sample. Every histopathology entity should have a counterpart in cytopathology, since both derive from the same entity undergoing the same pathological process. The difference is in the artifacts; thus an attempt was made to explain the artifacts of aspiration cytology so that histopathologists may understand the cytologic approach and learn to interpret aspiration cytology with confidence.
This color atlas covers etiology, incidence, clinical features, diagnostic features, immunochemistry, molecular biology and important differential diagnosis of various lesions of the body. It includes large number of microphotographs, around 1500 of all the common and uncommon lesions of the body that can be diagnosed by aspiration cytology. It also includes images of immunocytochemistry and other important ancillary tests of the lesions. Additionally, it includes a review chapter on interesting cases of fine needle aspiration cytology (FNAC) along with multiple choice questions. This book provides necessary information to the readers for the diagnosis and differential diagnosis of the body lesions with the help of FNAC.
This book offers a comprehensive guide to thyroid fine needle aspiration (FNA) cytology. Borderline/precursor tumors, which were introduced in the 4th edition of the WHO classification of thyroid tumors, are also incorporated. In this second edition, prominent international experts discuss the different approaches to thyroid FNA cytology employed in various countries such as Australia, Canada, China, Korea, Portugal, Switzerland, Taiwan, Thailand, Turkey, Ukraine, the USA, UK, Italy and Japan. The book not only covers key principles of thyroid cytopathology but also addresses technical aspects such as procedural complications, liquid-based cytology, immunocytochemistry, staining procedures, and potential pitfalls. Case-based descriptions and clinical findings, radiologic imaging, cytology, and histopathologic diagnosis – all complemented by a wealth of detailed photographs – will help reader understand and overcome many common dilemmas in daily practice. As such, the book represents an indispensable reference work for all cytopathologists, especially those practicing thyroid cytopathology.