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Many of the pesticides applied to food crops in this country are present in foods and may pose risks to human health. Current regulations are intended to protect the health of the general population by controlling pesticide use. This book explores whether the present regulatory approaches adequately protect infants and children, who may differ from adults in susceptibility and in dietary exposures to pesticide residues. The committee focuses on four major areas: Susceptibility: Are children more susceptible or less susceptible than adults to the effects of dietary exposure to pesticides? Exposure: What foods do infants and children eat, and which pesticides and how much of them are present in those foods? Is the current information on consumption and residues adequate to estimate exposure? Toxicity: Are toxicity tests in laboratory animals adequate to predict toxicity in human infants and children? Do the extent and type of toxicity of some chemicals vary by species and by age? Assessing risk: How is dietary exposure to pesticide residues associated with response? How can laboratory data on lifetime exposures of animals be used to derive meaningful estimates of risk to children? Does risk accumulate more rapidly during the early years of life? This book will be of interest to policymakers, administrators of research in the public and private sectors, toxicologists, pediatricians and other health professionals, and the pesticide industry.
Concern about health effects from exposure to pesticides in foods is growing as scientists learn more about the toxic properties of pesticides. The Delaney Clause, a provision of the Food, Drug and Cosmetic Act, prohibits tolerances for any pesticide that causes cancer in test animals or in humans if the pesticide concentrates in processed food or feeds. This volume examines the impacts of the Delaney Clause on agricultural innovation and on the public's dietary exposure to potentially carcinogenic pesticide residues. Four regulatory scenarios are described to illustrate the effects of varying approaches to managing oncogenic pesticide residues in food.
Although chemical pesticides safeguard crops and improve farm productivity, they are increasingly feared for their potentially dangerous residues and their effects on ecosystems. The Future Role of Pesticides explores the role of chemical pesticides in the decade ahead and identifies the most promising opportunities for increasing the benefits and reducing the risks of pesticide use. The committee recommends R&D, program, and policy initiatives for federal agriculture authorities and other stakeholders in the public and private sectors. This book presents clear overviews of key factors in chemical pesticide use, including: Advances in genetic engineering not only of pest-resistant crops but also of pests themselves. Problems in pesticide useâ€"concerns about the health of agricultural workers, the ability of pests to develop resistance, issues of public perception, and more. Impending shifts in agricultureâ€"globalization of the economy, biological "invasions" of organisms, rising sensitivity toward cross-border environmental issues, and other trends. With a model and working examples, this book offers guidance on how to assess various pest control strategies available to today's agriculturist.
Written by experienced quality assurance (QA) professionals and field laboratory researchers. Provides concrete ideas for establishing a compliance program and refining the compliance process. Outlines approaches that have resulted in successful compliance and describes methods of avoiding some of the common mistakes. Appendices contain the entire GLP Enforcement Response Policy, a question-and-answer section, examples of forms for submitting data to the EPA, and the EPA's penalty policy.
Resistance to conventional pesticides has been growing rapidly among all pests. Furthermore, there is increased public concern about the safety of conventional pesticides, and increased governmental restrictions have resulted in the need to identify new compounds that are safe and effective in controlling pests that are of concern to agriculture as well as to public and animal health. Biopesticides may aid in the control of such pests with fewer deleterious effects to the environment, people and animals. The U.S. Environmental Protection Agency (EPA) defines biopesticides as "pesticides derived from such natural materials as animals, plants, bacteria, and certain minerals" (www.epa.gov). According to the U.S. EPA's website in 2014 there were more than 430 registered biopesticides along with 1320 active product registrations. Biopesticides have seen a recent growth, which is partially due to increased advances in biotechnological tools for pest control. However, the growth has been largely spurred by the growing needs for new tools to fight pesticide resistance and safer and more benign means of pest management. This volume and the chapters contained within it resulted from the "Biopesticides: State of the Art and Future Opportunities" symposium held at the 246th ACS National Meeting in Indianapolis, Indiana, September 8-12, 2013. The symposium was comprised of 38 papers in five sessions: The Big Picture, Repellents and Attractants, Insecticides and Nematicides, Products from Genetic Improvements, and Economic, Regulatory and Future Needs. Biopesticides: State of the Art and Future Opportunities offers a wealth of information that will enrich the knowledge of experts in the field of biopesticide research.