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Offers a comprehensive and sytematic exploration of the human experimentation process. Dr. Katz examines and evaluates the authority which should be vested in each of the chief participants in this process- the investigator, subject, professions and state; as well as problems of decision-making which arise at its three basic stages: the formulation of research, the administration, and the review of research and its consequences.
In recent years, increasing concern has been voiced about the nature and extent of human experimentation and its impact on the investigator, subject, science, and society. This casebook represents the first attempt to provide comprehensive materials for studying the human experimentation process. Through case studies from medicine, biology, psychology, sociology, and law—as well as evaluative materials from many other disciplines—Dr. Katz examines the problems raised by human experimentation from the vantage points of each of its major participants—investigator, subject, professions, and state. He analyzes what kinds of authority should be delegated to these participants in the formulation, administration, and review of the human experimentation process. Alternative proposals, from allowing investigators a completely free hand to imposing centralized governmental control, are examined from both theoretical and practical perspectives. The conceptual framework of Experimentation with Human Beings is designed to facilitate not only the analysis of such concepts as "harm," "benefit," and "informed consent," but also the exploration of the problems raised by man's quest for knowledge and mastery, his willingness to risk human life, and his readiness to delegate authority to professionals and rely on their judgment.
There has been a rapid increase in the pace and scope of international collaborative research in developing countries in recent years. This study argues that whilst ethical regulation of biomedical research in Africa and other developing countries has attracted global attention, legal liability issues, such as the application of common law rules and the development of legally enforceable regulations, have been neglected. It examines some of the major research scandals in Africa and suggests a new ethical framework against which clinical trials could be conducted. The development of research guidelines in Uganda, Tanzania, Malawi and Nigeria are also examined as well as the role of ethics committees. Providing a detailed analysis of the law of negligence and its application to research ethics committees and their members, common law and constitutional forms of action and potential negligence claims, the book concludes by suggesting new protocols and frameworks, improved regulation and litigation. This book will be a valuable guide for students, researchers, and policy-makers with an interest in medical law and ethics, bioethics, customary law in Africa and regulation in developing countries.
Truly comprehensive in scope - and arranged in A-Z format for quick access - this eight-volume set is a one-source reference for anyone researching the historical and contemporary details of more than 170 major issues confronting American society. Entries cover the full range of hotly contested social issues - including economic, scientific, environmental, criminal, legal, security, health, and media topics. Each entry discusses the historical origins of the problem or debate; past means used to deal with the issue; the current controversy surrounding the issue from all perspectives; and the near-term and future implications for society. In addition, each entry includes a chronology, a bibliography, and a directory of Internet resources for further research as well as primary documents and statistical tables highlighting the debates.
This was first published in 2000: This text explores issues surrounding the use of human cadavers and human tissues in science and medicine. This is an area of increasing significance in contemporary society, as more and more techniques become available for manipulating human genes and human material (including embryos, body organs and brain tissue). These issues are explored through case studies from contemporary society. Some of the most topical issues examined include plastination of human bodies as an art form, the use of biopsies from surgical operations, the ethics of using human DNA and stem cells in research, and the debate surrounding the transplantation of animal tissue and organs into humans.
NATIONAL BOOK CRITICS CIRCLE AWARD WINNER • The first full history of Black America’s shocking mistreatment as unwilling and unwitting experimental subjects at the hands of the medical establishment. No one concerned with issues of public health and racial justice can afford not to read this masterful book. "[Washington] has unearthed a shocking amount of information and shaped it into a riveting, carefully documented book." —New York Times From the era of slavery to the present day, starting with the earliest encounters between Black Americans and Western medical researchers and the racist pseudoscience that resulted, Medical Apartheid details the ways both slaves and freedmen were used in hospitals for experiments conducted without their knowledge—a tradition that continues today within some black populations. It reveals how Blacks have historically been prey to grave-robbing as well as unauthorized autopsies and dissections. Moving into the twentieth century, it shows how the pseudoscience of eugenics and social Darwinism was used to justify experimental exploitation and shoddy medical treatment of Blacks. Shocking new details about the government’s notorious Tuskegee experiment are revealed, as are similar, less-well-known medical atrocities conducted by the government, the armed forces, prisons, and private institutions. The product of years of prodigious research into medical journals and experimental reports long undisturbed, Medical Apartheid reveals the hidden underbelly of scientific research and makes possible, for the first time, an understanding of the roots of the African American health deficit. At last, it provides the fullest possible context for comprehending the behavioral fallout that has caused Black Americans to view researchers—and indeed the whole medical establishment—with such deep distrust.
Through the first half of the twentieth century, emotions were a legitimate object of scientific study across a variety of disciplines. After 1945, however, in the wake of Nazi irrationalism, emotions became increasingly marginalized and postwar rationalism took central stage. Emotion remained on the scene of scientific and popular study but largely at the fringes as a behavioral reflex, or as a concern of the private sphere. So why, by the 1960s, had the study of emotions returned to the forefront of academic investigation? In Science and Emotions after 1945, Frank Biess and Daniel M. Gross chronicle the curious resurgence of emotion studies and show that it was fueled by two very different sources: social movements of the 1960s and brain science. A central claim of the book is that the relatively recent neuroscientific study of emotion did not initiate – but instead consolidated – the emotional turn by clearing the ground for multidisciplinary work on the emotions. Science and Emotions after 1945 tells the story of this shift by looking closely at scientific disciplines in which the study of emotions has featured prominently, including medicine, psychiatry, neuroscience, and the social sciences, viewed in each case from a humanities perspective.
This second edition of A Companion to Bioethics, fully revised and updated to reflect the current issues and developments in the field, covers all the material that the reader needs to thoroughly grasp the ideas and debates involved in bioethics. Thematically organized around an unparalleled range of issues, including discussion of the moral status of embryos and fetuses, new genetics, life and death, resource allocation, organ donations, AIDS, human and animal experimentation, health care, and teaching Now includes new essays on currently controversial topics such as cloning and genetic enhancement Topics are clearly and compellingly presented by internationally renowned bioethicists A detailed index allows the reader to find terms and topics not listed in the titles of the essays themselves
Science, as Andrew Goliszek proves in this compendious, chilling, and eye-opening book, has always had its dark side. Behind the bright promise of life-saving vaccines and life-enhancing technologies lies the true cost of the efforts to develop them. Knowledge has a price; often that price has been human suffering. The ethical limits governing use of the human body in experimentation have been breached, redefined, and breached again---from the moment the first plague-ridden corpse was heaved over the fortifications of a besieged medieval city to the use of cutting-edge gene therapy today. Those limits are in constant need of redefinition, for the goals and the techniques have become both more refined and more secretive. The German and Japanese human experiments of the 1930s and 1940s horrified the world when they came to light. These barbaric exercises in pseudoscience grew out of assumptions of racial superiority. The subjects were deemed subhuman; ordinary guidelines could therefore be suspended. What has happened in the decades since World War II has differed only in degree. Explicitly or implicitly, any organization or government that undertakes or sponsors scientific research applies some measure of human worth. Experimentation rests upon an equation that balances suffering against gain, the good of the collective against the rights of the individual, and the risk of unknown consequences against the rewards of scientific discovery. Everything depends upon who makes that equation. The sobering and gripping accumulation of evidence in this book proves exactly what has been justified in the name of science. The science of "eugenics" justified enforced sterilization. The need to gain an upper hand in the Cold War justified CIA experiments involving mind control and drugs. The desperate race to control nuclear proliferation was used to justify radiation experiments whose effects are still being felt today. Chemical warfare, gene therapy, molecular medicine: These subjects dominate headlines and even direct our government's foreign policy, yet the whole truth about the experimentation behind them has never been made public. Though not a cheering book, In the Name of Science is a crucially important one, and it deserves a wide audience. A biologist by training, Goliszek presents each topic clearly and explains fully its significance and implications. Connecting the history of scientific experimentation through time with the topics that are likely to dominate the future, he has performed an invaluable service. No other book on the market provides the research included here, or presents it with such persuasive force.