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The aim of this edited book is to provide health professionals, across a wide variety of specialisms, with a targeted access to evolutionary medicine. Throughout the book, the views of both medical and evolutionary scientists on the latest relevant research is presented with a focus on practical implications. The inclusion of boxes explaining the theoretical background as well as both a glossary for technical terms and a lay summary for non- specialists enable medical researchers, public health professionals, policy makers, physicians, students, scholars and the public alike to quickly and easily access appropriate information. This edited volume is thus relevant to anyone keen on finding out how evolutionary medicine can improve the health and well-being of people.
A new updated edition of the first integrated and comprehensive textbook to explain the principles of evolutionary biology from a medical perspective and to focus on how medicine and public health might utilise evolutionary biology.
Evolutionary Medicine is a textbook intended for use in undergraduate, graduate, medical school, and continuing medical education (CME) courses. Its professional illustrations and summaries of chapters and sections make its messages readily accessible.
Evolution and Medicine provides an accessible introduction to the new field of evolutionary medicine. Evolutionary concepts help explain why we remain vulnerable to disease, how pathogens and cancer cells evolve, and how the diseases that affected our evolutionary ancestors have shaped our biology. The book interweaves the presentation of evolutionary principles with examples that illustrate how an evolutionary perspective enhances our understanding of disease. It discusses the theory of evolution by natural selection, the genetic basis of evolutionary change, evolutionary life history theory, and host-pathogen coevolution, and uses these concepts to provide new insights into diseases such as cystic fibrosis, cancer, sexually transmitted diseases, and malaria, incorporating the latest research in rapidly developing fields such as epigenetics and the study of the human microbiome. The book concludes with a discussion of the ways in which recent, culturally constructed changes in the human environment are increasing the prevalence of man-made diseases such as diabetes and cardiovascular diseases, and are exacerbating socioeconomic disparities in health. Just as evolutionary biology is concerned with populations and with changes in populations over time, evolutionary medicine is concerned with the health of populations. Evolution and Medicine emphasizes the role of demographic processes in evolution and disease, and stresses the importance of improving population health as a strategy for improving the health of individuals. This accessible text is written primarily for physicians, biomedical scientists, and both premedical and medical students, and will appeal to all readers with a background or interest in medicine.
Evolution is the single most important idea in modern biology, shedding light on virtually every biological question, from the shape of orchid blossoms to the distribution of species across the planet. Until recently, however, the theory has had little impact on medical research or practice. Evolutionary Medicine shows how this is beginning to change. Collecting work from leaders in the field, this volume describes an array of new and innovative approaches to human health that are based on an appreciation of our long evolutionary history. For example, it shows how evolution helps to explain the complex relationship between our immune systems and the virulence and transmission of human viruses. It also shows how comparisons between how we live today and how our hunter-gatherer ancestors lived thousands of years ago illuminate a variety of contemporary ills, including obesity, lower-back pain, and insomnia. Evolutionary Medicine covers issues at every stage of life, from infancy (colic, jaundice, SIDS, parent-infant sleep struggles, ear infections, breast-feeding, asthma) to adulthood (sexually transmitted diseases, depression, overeating, addictions, child abuse, cardiovascular disease, breast and ovarian cancer) to old age (osteoporosis, geriatric sleep problems). Written for a wide range of students and researchers in medicine, anthropology, and psychology, it is an invaluable guide to this rapidly developing field.
Building on the success of their groundbreaking anthology Evolutionary Medicine (OUP, 1999), Wenda R. Trevathan, E. O. Smith, and James J. McKenna provide an up-to-date and thought-provoking introduction to the field with this new collection of essays. Ideal for courses in evolutionary medicine, medical anthropology, and the evolution of human disease, Evolutionary Medicine and Health: New Perspectives presents twenty-three original articles that examine how human evolution relates to a broad range of contemporary health problems including infectious, chronic, nutritional, and mental diseases and disorders. Topics covered include disease susceptibility in cultural context, substance abuse and addiction, sleep disorders, preeclampsia, altitude-related hypoxia, the biological context of menstruation, and the role of stress in modern life. An international team of preeminent scholars in biological anthropology, medicine, biology, psychology, and geography contributed the selections. Together they represent a uniquely integrative and multidisciplinary approach that takes into account the dialogue between biology and culture as it relates to understanding, treating, and preventing disease. A common theme throughout is the description of cases in which biological human development conflicts with culturally based individual behaviors that determine health outcomes. Detailed, evidence-based arguments make the case that all aspects of the human condition covered in the volume have an evolutionary basis, while theoretical discussions using other empirical evidence critique the gaps that still remain in evolutionary approaches to health. Evolutionary Medicine and Health: New Perspectives features an introductory overview that covers the field's diverse array of topics, questions, lines of evidence, and perspectives. In addition, the editors provide introductions to each essay and an extensive bibliography that represents a state-of-the-art survey of the literature. A companionwebsite at www.oup.com/us/evolmed offers a full bibliography and links to source articles, reports, and databases. Written in an engaging style that is accessible to students, professionals, and general readers, this book offers a unique look at how an evolutionary perspective has become increasingly relevant to the health field and medical practice.
A founder of the field of evolutionary medicine uses his decades of experience as a psychiatrist to provide a much-needed new framework for making sense of mental illness. Why do I feel bad? There is real power in understanding our bad feelings. With his classic Why We Get Sick, Dr. Randolph Nesse helped to establish the field of evolutionary medicine. Now he returns with a book that transforms our understanding of mental disorders by exploring a fundamentally new question. Instead of asking why certain people suffer from mental illness, Nesse asks why natural selection has left us all with fragile minds. Drawing on revealing stories from his own clinical practice and insights from evolutionary biology, Nesse shows how negative emotions are useful in certain situations, yet can become overwhelming. Anxiety protects us from harm in the face of danger, but false alarms are inevitable. Low moods prevent us from wasting effort in pursuit of unreachable goals, but they often escalate into pathological depression. Other mental disorders, such as addiction and anorexia, result from the mismatch between modern environment and our ancient human past. And there are good evolutionary reasons for sexual disorders and for why genes for schizophrenia persist. Taken together, these and many more insights help to explain the pervasiveness of human suffering, and show us new paths for relieving it by understanding individuals as individuals.
Clinicians and scientists are increasingly recognising the importance of an evolutionary perspective in studying the aetiology, prevention, and treatment of human disease; the growing prominence of genetics in medicine is further adding to the interest in evolutionary medicine. In spite of this, too few medical students or residents study evolution. This book builds a compelling case for integrating evolutionary biology into undergraduate and postgraduate medical education, as well as its intrinsic value to medicine. Chapter by chapter, the authors - experts in anthropology, biology, ecology, physiology, public health, and various disciplines of medicine - present the rationale for clinically-relevant evolutionary thinking. They achieve this within the broader context of medicine but through the focused lens of maternal and child health, with an emphasis on female reproduction and the early-life biochemical, immunological, and microbial responses influenced by evolution. The tightly woven and accessible narrative illustrates how a medical education that considers evolved traits can deepen our understanding of the complexities of the human body, variability in health, susceptibility to disease, and ultimately help guide treatment, prevention, and public health policy. However, integrating evolutionary biology into medical education continues to face several roadblocks. The medical curriculum is already replete with complex subjects and a long period of training. The addition of an evolutionary perspective to this curriculum would certainly seem daunting, and many medical educators express concern over potential controversy if evolution is introduced into the curriculum of their schools. Medical education urgently needs strategies and teaching aids to lower the barriers to incorporating evolution into medical training. In summary, this call to arms makes a strong case for incorporating evolutionary thinking early in medical training to help guide the types of critical questions physicians ask, or should be asking. It will be of relevance and use to evolutionary biologists, physicians, medical students, and biomedical research scientists.
The next time you get sick, consider this before picking up the aspirin: your body may be doing exactly what it's supposed to. In this ground-breaking book, two pioneers of the science of Darwinian medicine argue that illness as well as the factors that predispose us toward it are subject to the same laws of natural selection that otherwise make our bodies such miracles of design. Among the concerns they raise: When may a fever be beneficial? Why do pregnant women get morning sickness? How do certain viruses "manipulate" their hosts into infecting others? What evolutionary factors may be responsible for depression and panic disorder? Deftly summarizing research on disorders ranging from allergies to Alzheimer's, and form cancer to Huntington's chorea, Why We Get Sick, answers these questions and more. The result is a book that will revolutionize our attitudes toward illness and will intrigue and instruct lay person and medical practitioners alike.
A groundbreaking, evidence-based text to the growing field of evolutionary medicine Evidence-Based Evolutionary Medicine offers a comprehensive review of the burgeoning field of evolutionary medicine and explores vital topics such as evolution, ecology, and aging as they relate to mainstream medicine. The text integrates Darwinian principles and evidence-based medicine in order to offer a clear picture of the underlying principles that reflect how and why organisms have evolved on a cellular level. The authors—noted authorities in their respective fields—address evolutionary medicine from a developmental cell-molecular perspective. They explore the first principles of physiology that explain the generation of existing tissues, organs, and organ systems. The text offers an understanding of the overall biology as a vertically integrated whole, from unicellular to multicellular organisms. In addition, it addresses clinical diagnostic and therapeutic approaches, both traditional and cell-homeostatic. This groundbreaking text: • Offers a much-needed, logical, and fundamental approach to biology and medicine • Provides a clear explanation of complex physiology and pathophysiology • Integrates topics like evolution, ecology and aging into mainstream medicine, making them more relevant • Contains the first evidence-based text on evolutionary medicine Written for medical and graduate students in biology, physiology, anatomy, endocrinology, reproductive biology, medicine, pathology, systems biology, this vital resource offers a unique text of both biology as an integrated whole with universal properties; and of medicine seeing the individual as a whole, not an inventory of parts and diseases.