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The papers included in this book were presented at the Baltimore Conference on Ethics in 1995. The purpose of this conference was to bring together ethicists, psychiatrists, researchers, family members, consumers, and representatives of government, industry and academia to discuss the following issues: History and Ethics of Neurobiological Research with Human Subjects, Current Practices, Informed Consent, Government Oversight/Institutional Review Boards, and the Patient and Family Perspective. Over the past 40 years, there has been a significant increase in research on neurobiological disorders for basic scientific knowledge, and to develop new treatment therapies. This has led to significant advances in the treatment of schizophrenia, manic-depression and other disorders which have improved the lives of thousands. Public attention has been raised recently over the potential vulnerability of patients with neurobiological disorders who participate in such research since these patients often s
This handbook is a ‘one-stop shop’ for current information, issues and challenges in the fields of research ethics and scientific integrity. It provides a comprehensive coverage of research and integrity issues, both within researchers’ ‘home’ discipline and in relation to similar concerns in other disciplines. The handbook covers common elements shared by disciplines and research professions, such as consent, privacy, data management, fraud, and plagiarism. The handbook also includes contributions and perspectives from academics from various disciplines, treating issues specific to their fields. Readers are able to quickly source the most comprehensive and up-to-date information, protagonists, issues and challenges in the field. Experienced researchers keen to assess their own perspectives, as well as novice researchers aiming to establish the field, will equally find the handbook of interest and practical benefit. It saves them a great deal of time in sourcing the disparate available material in these fields and it is the first ‘port of call’ for a wide range of researchers, research advisors, funding agencies and research reviewers.The most important feature is the handbook’s ability to provide practical advice and guidance to researchers in a wide range of disciplines and professions to help them ‘think through’ their approach to difficult questions related to the principles, values and standards they need to bring to their research practice.
Recent scandals and controversies, such as data fabrication in federally funded science, data manipulation and distortion in private industry, and human embryonic stem cell research, illustrate the importance of ethics in science. Responsible Conduct of Research, now in a completely updated second edition, provides an introduction to the social, ethical, and legal issues facing scientists today.
Medicine in the twenty-first century is increasingly reliant on research to guarantee the safety and efficacy of medical interventions. As a result, the need to understand the ethical issues that research generates is becoming essential. This volume introduces the principal areas of concern in research on human subjects, offering a framework for understanding research ethics, and the relationship between ethics and compliance. Research Ethics brings together leading scholars in bioethics and the topics covered include the unique concerns that arise in specific areas of research such as gene therapy and stem cell research. Individual chapters also address the ethical issues that occur when conducting research with specific populations such as infants or adolescents, and the volume looks at important emerging questions in human subjects research, namely financial conflicts of interest and the interpretation of scientific data.
Animals are widely used in neuroscience research to explore biological mechanisms of nervous system function, to identify the genetic basis of disease states, and to provide models of human disorders and diseases for the development of new treatments. To ensure the humane care and use of animals, numerous laws, policies, and regulations are in place governing the use of animals in research, and certain animal regulations have implications specific to neuroscience research. To consider animal research regulations from a global perspective, the IOM Forum on Neuroscience and Nervous System Disorders, in collaboration with the National Research Council and the Institute for Laboratory Animal Research, held a workshop in Buckinghamshire, UK, July 26-27, 2011. The workshop brought together neuroscientists, legal scholars, administrators, and other key stakeholders to discuss current and emerging trends in animal regulations as they apply to the neurosciences. This document summarizes the workshop.
"A rich guide for understanding the evolving research landscape in psychology, including changes to core research ethics concepts such as informed consent, privacy, and risk of harm. This handbook offers a thorough and authoritative discussion of the ethical issues in conducting research with human participants. Each chapter poses an important ethical question, considers the relevant factors for addressing the question, and presents guidance for investigators. Topics include: informed consent, deception, risk/benefit ratio, data security, authorship, conflicts of interest, fairness and equity when collaborating with researchers in resource-poor settings, and more. While psychological research with humans still takes place in the investigator's laboratory and field, there is an increasing trend toward multiple investigators and interdisciplinary research projects owing to the complexity of modern research questions. Furthermore, technology has changed dramatically and affects all psychological researchers, whether they are working individually or in large teams. With its comprehensive scope and practical guidance, this book will serve as an invaluable aid to understanding and navigating the ethical challenges that confront new and seasoned researchers alike"--
This volume examines everyday ethical issues that clinicians encounter as they go about their work caring for people who have severe and persistent mental disorders. It prompts and provokes readers to recognize, to analyze, to reflect upon, and to respond to the range of commonplace ethical concerns that arise in community mental health care practice.
This textbook provides a brief history of human experimentation and reviews various theories of ethics from which the principles and rules that govern this research are derived. All relevant international documents and national regulations, policies and memoranda are referred to extensively to assist in addressing issues that regularly arise during the course of research involving human subjects. It includes case examples and exercises and is of interest to students and experienced researchers.
Scientific research ethics vary by discipline and by country, and this analysis sought to understand those variations. The authors reviewed literature and conducted interviews to provide researchers, government officials, and others who create, modify, and enforce ethics in scientific research around the world with an understanding of how ethics are created, monitored, and enforced across scientific disciplines and across international borders.
New advances in neuroscience promise innovations in national security, especially in the areas of law enforcement, intelligence collection, and armed conflict. But ethical questions emerge about how we can, and should, use these innovations. This book draws on the open literature to map the development of neuroscience, particularly through funding by the Defense Advanced Research Projects Agency, in certain areas like behavior prediction, behavior modification, and neuroenhancement, and its use in the creation of novel weapons. It shows how advances in neuroscience and new technologies raise ethical issues that challenge the norms of law enforcement, intelligence collection, and armed conflict, broadly grouped under the term "national security." Increasing technological sophistication without attention to ethics, this book argues, risks creating conditions for the development of "dual-use" technologies that may be prone to misuse, are grounded in an incomplete understanding of the brain, or are based on a limited view of the political contexts in which these technologies arise. A concluding section looks at policy and regulatory options that might promote the benefits of emerging neuroscience, while mitigating attendant risks. Key Features: First broad survey of the ethics of neuroscience as it applies to national security Innovative ethical analysis over a range of cross-cutting technologies including behavior prediction and modification tools, human enhancement, and novel lethal and nonlethal weapons Ethical analysis covering all stages from the development, testing, and use (or misuse) of these technologies; and decisions from the individual scientist to the nation state Strong policy focus at multiple levels, from self-governance to international regulation Combination of philosophical analysis with grounded, practical recommendations