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Richard Rudgley's first book, Essential Substances, was the winner of the British Museum Prometheus Award and hailed as a masterpiece by the Director of Harvard Botanical Museum. It is still one of the few books to have explored the role of drugs in the religious, political, economic and sexual life of our species from prehistory to the present day, covering a range of cultures as diverse as the Amazonian Indians, the Scythians of the ancient world and the witches of Medieval Europe alongside inner city crack and drugs in the counterculture. It is a magical tour of the bizarre world of intoxicants peopled by tribesmen and mystics, statesmen and writers, housewives and yuppies. Rudgley cogently shows how the significance of these substances extends beyond simple pleasure to the economic, political, and sexual life of a community. In the process, he challenges our assumptions that deem certain intoxicants socially and legally acceptable, while others remain taboo. Essential Substances remains a timely, much-needed reconsideration of the roles intoxicants play in our lives and society. Added for this edition is a new appendix, 'A Psychoactive Bestiary'. 'A splendid contribution to the new wave of scholarship that is forcing a different approach to our ages-old fascination with hallucinogenic plants and altered states. Richard Rudgley is to be congratulated' - Terence McKenna, author of Food of the Gods and True Hallucinations 'Should be required reading for all legislators who think disliked substances can be made to vanish by means of criminal sanctions' - Andrew Weil MD, author of The Natural Mind Richard Rudgley is a critically acclaimed author whose books have been translated into twelve languages. The author of several books, he has also written and presented several documentaries that have aired on Channel 4 in the United Kingdom and on various channels internationally. Arktos has also republished his books Wildest Dreams: An Anthology of Drug-Related Literature, which collects writings both ancient and modern describing the drug experience; and Barbarians, which is about the Dark Ages.
Synthesis of Essential Drugs describes methods of synthesis, activity and implementation of diversity of all drug types and classes. With over 2300 references, mainly patent, for the methods of synthesis for over 700 drugs, along with the most widespread synonyms for these drugs, this book fills the gap that exists in the literature of drug synthesis. It provides the kind of information that will be of interest to those who work, or plan to begin work, in the areas of biologically active compounds and the synthesis of medicinal drugs. This book presents the synthesis of various groups of drugs in an order similar to that traditionally presented in a pharmacology curriculum. This was done with a very specific goal in mind – to harmonize the chemical aspects with the pharmacology curriculum in a manner useful to chemists. Practically every chapter begins with an accepted brief definition and description of a particular group of drugs, proposes their classification, and briefly explains the present model of their action. This is followed by a detailed discussion of methods for their synthesis. Of the thousands of drugs existing on the pharmaceutical market, the book mainly covers generic drugs that are included in the WHO's Essential List of Drugs. For practically all of the 700+ drugs described in the book, references (around 2350) to the methods of their synthesis are given along with the most widespread synonyms. Synthesis of Essential Drugs is an excellent handbook for chemists, biochemists, medicinal chemists, pharmacists, pharmacologists, scientists, professionals, students, university libraries, researchers, medical doctors and students, and professionals working in medicinal chemistry. * Provides a brief description of methods of synthesis, activity and implementation of all drug types* Includes synonyms* Includes over 2300 references
This report presents the recommendations of the WHO Expert Committee responsible for updating the WHO Model List of Essential Medicines. The first part contains a progress report on the new procedures for updating the Model List and the development of the WHO Essential Medicines Library. It continues with a section on changes made in revising the Model List followed by a review of some sections such as hypertensive medicines and fast track procedures for deleting items. Annexes include the 13th version of the Model List and items on the list sorted according to their 5-level Anatomical Therapeutic Chemical classification codes.
Diet and Health examines the many complex issues concerning diet and its role in increasing or decreasing the risk of chronic disease. It proposes dietary recommendations for reducing the risk of the major diseases and causes of death today: atherosclerotic cardiovascular diseases (including heart attack and stroke), cancer, high blood pressure, obesity, osteoporosis, diabetes mellitus, liver disease, and dental caries.
In a convenient, single-source reference, this book examines plant growth substances and their relationship to a wide range of physiological processes, ranging from seed germination through the death of the plant. If offers a clear illustration of the pragmatic uses of plant substances in agriculture and demonstrates how basic laboratory research has translated into increased production and profit for the grower. This work begins by building a solid foundation in the subject, which contains historical aspects and fundamental concepts, and provides a methodology for extraction, purification, and quantification of plant growth substances. This forms the basis for understanding the ensuing chapters that explore the many processes involving plant growth substances, including: * seed germination * seedling growth * rooting * dormancy * juvenility * maturity * senescence * flowering * abscission * fruit set * fruit growth * fruit development * premature drop * ripening * promotion of fruit drop * tuberization * photsynthesis * weed control. Providing a detailed examination of plant growth substances and their relationships to specific physiological plant processes, Plant Growth Substances gives students, researchers, and professionals a much needed reference.
“A well-founded and presented description of the integral role that psychoactive substances played in ancient societies. . . . A unique addition to ancient history collections.”—Choice “Very informative, well referenced, and well illustrated.”—Latin American Antiquity “A diverse and interesting introduction to the evidence for psychoactive use in the past, including consideration of the physical techniques and interpretative methods for understanding these practices.”—Journal of Psychedelic Studies "This well-researched and fascinating volume not only demonstrates the important cultural role of psychoactive substances in ancient societies but also points the way to an emerging research field. The unveiling of the past history of drug use becomes a lesson for present-day society."--Jan G. Bruhn, founding editor, Journal of Ethnopharmacology "Presents a broad overview of drug plants and fermented beverages by using anthropological, ethnological, archaeological, iconographic, chemical, and botanical approaches. Essential reading."--Elisa Guerra Doce, author of Drugs in Prehistory: Archaeological Evidence of the Use of Psychoactive Substances in Europe Mind-altering substances have been used by humans for thousands of years. In fact, ancient societies sometimes encouraged the consumption of drugs. Focusing on the archaeological study of how various entheogens have been used in the past, this volume examines why humans have social and psychological needs for these substances. Contributors trace the long-term use of drugs in ancient cultures and highlight the ways they evolved from being sacred to recreational in more modern times. By analyzing evidence of these substances across a diverse range of ancient cultures, the contributors explore how and why past civilizations harvested, manufactured, and consumed drugs. Case studies examine the use of stimulants, narcotics, and depressants by hunter-gatherers who roamed Africa and Eurasia, prehistoric communities in North and South America, and Maya kings and queens. Offering perspectives from many different fields of study, contributors illustrate the wide variety of sources and techniques that can provide information about materials that are often invisible to archaeologists. They use advanced biomolecular procedures to identify alkaloids and resins on cups, pipes, and other artifacts. They interpret paintings on vases and discuss excavations of breweries and similar sites. Uncovering signs of drugs, including ayahuasca, peyote, ephedra, cannabis, tobacco, yaupon, vilca, and maize and molle beer, they explain how psychoactive substances were integral to interpersonal relationships, religious practices, and social cohesion in antiquity. Scott M. Fitzpatrick, professor of archaeology at the University of Oregon, is coeditor of Island Shores, Distant Pasts: Archaeological and Biological Approaches to the Pre-Columbian Settlement of the Caribbean. Contributors: Quetta Kaye | Victor D. Thompson | Thomas J. Pluckhahn | Sean Rafferty | Mark Merlin | Matt Sayre | Constantino Manuel Torres | Zuzana Chovanec | Jennifer A. Loughmiller-Newman | Justin Jennings | Daniel M. Seinfeld | Shannon Tushingham | Scott M. Fitzpatrick
Fundamental Toxicology is a concise and comprehensive review of toxicology. It is based on the highly successful Fundamental Toxicology for Chemists and has been enriched and expanded. Every chapter in this new edition has been revised and updated, and four new chapters have been added. With contributions from internationally recognised experts in their field, this broad-based introduction to the topic covers both well-established and rapidly developing areas of toxicology, such as toxicogenomics, reproductive toxicology, behavioural toxicology and ecotoxicology. The book was written and published with the support of the International Union of Pure and Applied Chemistry (IUPAC). The book includes new information on: risk assessment and risk management; toxicogenomics; effects of toxic substances on the human body; environmental distribution of chemicals and ecotoxicology; clinical toxicology; pharmaceutical toxicology; and aspects of laboratory measurement and safe laboratory practice. Fundamental Toxicology is ideal for students and includes extensive pedagogical features, such as an extensive glossary, a bibliography after each chapter and recommended further reading. It is also designed for teachers and lecturers, especially those who may be teaching toxicology for the first time. Included is a suggested curriculum for using the text to teach toxicology to students from various scientific disciplines. Professionals working in toxicology and related fields will find this an invaluable guide.