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This book provides comprehensive knowledge on diseases in livestock that are caused by viruses, parasites and bacteria. Emerging and re-emerging pathogens are presented in detail for various animal groups and in-depth insights into pathogenesis and epidemiology will be provided for each of them. In addition, state-of-the-art treatment possibilities, control measures as well as vaccination strategies are discussed. The recent years have witnessed a sharp increase in the number of emerging and re-emerging infectious diseases of livestock and many of these, including Influenza, Corona and Hanta are of public health importance. The reasons for this development are manifold:changes in the climate, life cycle of vectors and increased global travel. Also, due to extensive deforestation, livestock are increasingly coming in direct contact with wild animals that are reservoirs of many emerging pathogens. Recent progress in diagnosis and management of emerging infectious diseases are also topic of this book.
Color Atlas of Equine Pathology offers a practical guide to identifying equine diseases, presenting a single resource with more than 1000 images showing predominantly gross pathology. Organized by body systems, the book allows for picture matching during or after an equine necropsy. In this user-friendly atlas, each chapter takes a common format, presenting the disease process as well as congenital, degenerative, inflammatory, and neoplastic sequences, with text boxes offering quick reference to key information. The book begins with an introductory chapter summarizing the principles of the equine field necropsy, and subsequent organ-based chapters depict gross features of disease, focusing on macroscopic digital images supplemented by histology and immunohistochemistry when necessary. Some clinical information for correlation with pathology is included. Color Atlas of Equine Pathology is an essential resource for diagnostic veterinary pathologists and pathology residents, as well as for equine practitioners performing necropsies in the field.
Equine Neurology, Second Edition provides a fully updated new edition of the only equine-specific neurology book, with comprehensive, clinically oriented information. Offers a complete clinical reference to neurologic conditions in equine patients Takes a problem-based approach to present a clinically oriented perspective Presents new chapters on imaging the nervous system, neuronal physiology, sleep disorders, head shaking, differential diagnosis of muscle trembling and weakness, and cervical articular process joint disease Covers the basic principles of neurology, clinical topics such as the initial exam, differentials, and neuropathology, and specific conditions and disorders Includes access to a companion website offering video clips demonstrating presenting signs
The Geographical Distribution of Animal Viral Diseases attempts to shed some light on the global distribution of 110 different viral diseases, mainly of livestock and companion animals. The world literature was screened for 110 different viruses, and maps were prepared. These maps delineate the global distribution of pathogenic viruses based on authenticated reports from a variety of reliable sources. Four viruses were categorized as affecting more than one species to a significant degree (astrovirus, rabies, rotaviruses, and Rift Valley fever). The largest number of maps involved viruses that affect humans. Of the 28 viruses a large number were from the California encephalitis group. Ten of the 28 viruses were reported only in the Eastern Hemisphere, 14 only in the Western Hemisphere, and four were worldwide. Birds were the next most frequently affected group with the 15 viruses, followed by pigs with 14 viruses. Overall the vector-borne viruses appear to have much sharper and clear-cut geographical boundaries than the others.
Interpretation of Equine Laboratory Diagnostics offers a comprehensive approach to equine laboratory diagnostics, including hematology, clinical chemistry, serology, body fluid analysis, microbiology, clinical parasitology, endocrinology, immunology, and molecular diagnostics. Offers a practical resource for the accurate interpretation of laboratory results, with examples showing real-world applications Covers hematology, clinical chemistry, serology, body fluid analysis, microbiology, clinical parasitology, endocrinology, immunology, and molecular diagnostics Introduces the underlying principles of laboratory diagnostics Provides clinically oriented guidance on performing and interpreting laboratory tests Presents a complete reference to establish and new diagnostic procedures Offers a practical resource for the accurate interpretation of laboratory results, with examples showing real-world applications Covers hematology, clinical chemistry, serology, body fluid analysis, microbiology, clinical parasitology, endocrinology, immunology, and molecular diagnostics Introduces the underlying principles of laboratory diagnostics Provides clinically oriented guidance on performing and interpreting laboratory tests Presents a complete reference to established and new diagnostic procedures
Few areas of biomedical research provide greater opportunities to capitalize upon the revolution in genomics and molecular biology than gene therapy. This is particularly true for the brain and nervous system, where gene transfer has become a key technology for basic research and has recently been translated to human therapy in several landmark clinical trials. Gene Therapy in the Brain: From Bench to Bedside represents the definitive volume on this subject. Edited by two pioneers of neurological gene therapy, this volume contains contributions by leaders who helped to create the field as well as those who are expanding the promise of gene therapy for the future of basic and clinical neuroscience. Drawing upon this extensive collective experience, this book provides clear and informative reviews on a variety of subjects which would be of interest to anyone who is currently using or contemplating exploring gene therapy for neurobiological applications. Basic gene transfer technologies are discussed, with particular emphases upon novel vehicles, immunological issues and the role of gene therapy in stem cells. Numerous research applications are reviewed, particularly in complex fields such as behavioral neurobiology. Several preclinical areas are also covered which are likely to translate into clinical studies in the near future, including epilepsy, pain and amyotrophic lateral sclerosis. Among the most exciting advances in recent years has been the use of neurological gene therapy in human clinical trials, including Parkinson's disease, Canavan disease and Batten disease. Finally, readers will find "insider" information on technological and regulatory issues which can often limit effective translation of even the most promising idea into clinical use. This work provides up-to-date information and key insights into those gene therapy issues which are important to both scientists and clinicians focusing upon the brain and central nervous system.
Virology is in a sense both one of the most important precursors and one of the most significant beneficiaries of structural and cellular molecular biology. Numerous breakthroughs in our understanding of the molecular interactions of viruses with host cells are ready for translation into medically important applications such as the prevention and treatment of viral infections. This book collects a wide variety of examples of frontline research into molecular aspects of viral infections from virological, immunological, cell- and molecular-biological, structural, and theoretical perspectives. - Contributors are world leaders in their fields of study and represent prestigious academic and research institutions - Review articles vary vastly in scope: some focus on a narrowly defined scientific problem of one particular virus with careful introduction for the non-specialist; others are essays in general and comparative virology with forays into specific viral species or molecules - The different perspectives complement each other and collectively the contributions provide an impression of the fast-moving frontlines of virology while showing how the problems have evolved - Structural data are presented through high-quality illustrations
Equine Clinical Immunology offers comprehensive information on equine immunological disorders. • Provides a complete, equine-specific reference on clinical immunology • Focuses on clinically relevant information for the diagnosis and treatment of horses with immune disorders • Illustrates the concepts discussed using drawings, photographs, and tables • Presents key concepts, clinical assessment information, and treatment approaches in text boxes for ease of use • Offers a practical, clinically oriented approach ideal for equine specialists
Ideal for both practitioners and students, this comprehensive resource covers the diagnosis, treatment, and prevention of infectious disease in horses. Organized by infectious agent — virus, bacterial and rickettsial, protazoal, and fungal — it includes complete coverage of the individual diseases caused by each type of agent. A section on clinical problems examines conditions such as ocular infections, CNS infections, and skin infections. It also addresses the importance of preventing and controlling infectious disease outbreaks with coverage of epidemiology, biosecurity, antimicrobial therapy, and recognizing foreign equine diseases. - Full-color photos and illustrations provide clear, accurate representations of the clinical appearance of infectious diseases. - Features the most recent information on the global threat of newly emergent diseases such as African Horse Sickness. - Includes a comprehensive section on the prevention and control of infectious diseases. - More than 60 expert contributors share their knowledge and expertise in equine infectious disease. - A companion CD-ROM, packaged with the book, includes complete references linked to PubMed. - NEW! The most up-to-date coverage of equine piroplasmosis reflects what experts have learned as more outbreaks of this tick-borne disease have occurred in the US. - NEW! Content on EHV-1 keeps you current on the diagnosis and treatment of this potentially serious disease in horses. - NEW! Information on how global climate changes are creating more diseases in horses keeps you alert to the possibilities of new and emerging diseases worldwide. - NEW! Expanded coverage of biosecurity on farms and in veterinary practices helps you develop an effective biosecurity program and emphasizes how to isolate or eliminate the source of infectious agents. - NEW! Additional clinical algorithms offer detailed prevention strategies in addition to diagnostic and therapeutic guidelines. - NEW! New appendix of product and diagnostic test kit manufacturers on the companion website, gives you access to the most current products and advances available in equine medicine.
- ALL-NEW topics provide updates on infectious diseases, including herpesvirus, equine granulocytic anaplasmosis, and lawsonia infection and proliferative enteropathy; pain diagnosis and multimodal management; management of thoracic and airway trauma, imaging, endoscopy, and other diagnostic procedures for the acute abdomen; and neurologic injury. - 212 concise, NEW chapters include both a succinct guide to diagnosis of disorders and a detailed discussion of therapy. - NEW images demonstrate advances in various imaging techniques. - Thoroughly updated drug appendices, including all-new coverage of drug dosages for donkeys and mules, provide a handy, quick reference for the clinical setting.