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Enzyme immobilization on solid supports has been considered for a long time as an attractive solution to perform sophisticated organic synthesis, which is required in the preparation of fine pharmaceutical chemicals. But in the late 1990s, the tremendous progress in molecular biology fundamentals opened up the possibility of feeding a toolbox for b
This book is the first book in English on nanotechnology and nanomaterials integrating with enzymatic systems, with a focus on nanoparticles and biological applications. It covers comprehensively the relevant topics to understand the development of enzyme nanoparticles as it relates to the complicated structures of enzyme nanoparticles and their functionalization and immobilization on to various supports. The preparation of enzyme nanoparticles, their kinetic properties and applications after immobilization of the immobilized enzyme nanoparticles is described. The use of colour images in all formats of the book will improve the understanding of the topics covered. The book offers an integration of Enzymology and Nanotechnology and provides the latest information on preparation of enzyme nanoparticles, their characterization, their functionalization and immobilization on to various supports and thereafter their kinetic properties and applications in various industries with special reference to Biosensor Technology. - Focus on enzyme nanotechnology, given the wide appeal of enzymes for diagnostics, therapy and biocatalysis - Provision of a general background to the topic, but also a detailed description of synthesis, preparation and applications
Stimuli-Responsive Nanocarriers: Recent Advances in Tailor-Made Therapeutics compiles dispersed knowledge into a complete and comprehensive source to help researchers understand and progress stimuli-responsive nanocarriers. The book contains recent advancements made in the field of stimuli-responsive nanocarriers with their application in controlled drug delivery against various diseases. It focuses on the design, mechanism, construction, therapeutic application and future challenges of stimuli-responsive nanocarriers which will help new researchers in designing next generation tailor-made advanced therapeutics. Finally, the book covers future aspects and challenges present in the route of development of stimuli responsive nanocarriers for disease therapeutics. Various recent advances and biomedical applications assembled in this book will guide scientists on how to design and develop novel controlled drug release systems. - Provides comprehensive knowledge of basic design, mechanism and construction of nanocarrier based stimuli-responsive drug releases - Explores various nanocarriers characteristically used in the development of stimuli-responsive drug release systems - Envisages future opportunities, challenges and implementation of nanocarrier based stimuli-responsive drug release systems in disease therapeutics
Nanomaterials for Biocatalysis explains the fundamental design concepts and emerging applications of nanoscale biocatalysts, such as bioconversions, bioelectronics, biosensors, biocomputing and therapeutic applications. Nano-biocatalysts refers to the incorporation of enzymes into nanomaterials. These enzyme-enhanced nanocarriers have many advantages, including low mass transfer limitation, high enzyme capacity, better stabilization, and the formation of single-enzyme nanoparticles. Smart nanocontainers have been developed for the smart release of their embedded active substances. These smart releases can be obtained by using smart coatings as their outer nanoshells. In addition, these nanocontainers could protect the enzymes from chemical or metabolic alterations on their delivering pathways towards the target. This is an important reference source for materials scientists and chemical engineers who want to know more about how nanomaterials are being used for biocatalysis applications. Explains the major fabrication techniques and applications of nanobiocatalysts Shows how nanobiocatalysts are used in a variety of environmental and biomedical sectors Assesses the major challenges associated with the widespread manufacture of nanobiocatalysts
Stimuli-Responsive Nanocarriers for Targeted Drug Delivery presents a comprehensive overview of the most significant physical and chemical stimuli-responsive drug delivery systems. This book reviews targeted and controlled drug delivery systems and how nanocarriers can be used to improve the pharmacokinetics of drugs in biological systems, such as increasing utilization rate and reducing toxicity and side effects. After a key introduction to the topic, a range of nanocarrier types is assessed before exploring the clinical translation challenges and considerations involved.This book is a useful resource for researchers and postgraduate students in the fields of materials science, nanotechnology, pharmaceutical science, and medicinal chemistry. - Offers an in-depth look at the basic and fundamental aspects of stimuli-responsive materials, mechanisms, structure, synthesis and properties - Provides information about well-defined categorization for stimuli-responsive drug delivery system based on different triggering mechanisms to its reader - Reviews basic concepts and the latest research involving advances in stimuli-responsive drug delivery systems in controlled-release drugs - Discusses novel approaches and challenges for scaling-up and commercialization of stimuli-responsive polymers
Reviews recent advances in catalytic biodiesel synthesis, highlighting various nanocatalysts and nano(bio)catalysts developed for effective biodiesel production Nano- and Biocatalysts for Biodiesel Production delivers an essential reference for academic and industrial researchers in biomass valorization and biofuel industries. The book covers both nanocatalysts and biocatalysts, bridging the gap between homogenous and heterogenous catalysis. Readers will learn about the techno-economical and environmental aspects of biodiesel production using different feedstocks and catalysts. They will also discover how nano(bio)catalysts can be used as effective alternatives to conventional catalysts in biodiesel production due to their unique properties, including reusability, high activation energy and rate of reaction, easy recovery, and recyclability. Readers will benefit from the inclusion of: Introductions to CaO nanocatalysts, zeolite nanocatalysts, titanium dioxide-based nanocatalysts and zinc-based in biodiesel production An exploration of carbon-based heterogeneous nanocatalysts for the production of biodiesel Practical discussions of bio-based nano catalysts for biodiesel production and the application of nanoporous materials as heterogeneous catalysts for biodiesel production An analysis of the techno-economical considerations of biodiesel production using different feedstocks Nano- and Biocatalysts for Biodiesel Production focuses on recent advances in the field and offers a complete and informative guide for academic researchers and industrial scientists working in the fields of biofuels and bioenergy, catalysis, biotechnology, bioengineering, nanotechnology, and materials science.
Approx.296 pages - Focuses on integrative approaches of the enzyme nanoparticle synthesis and its applications on biomedicine, biosensors, and biocatalysis - Encloses the potential challenges and developments of enzyme incorporated nanoparticles - Discusses the vital activities of nanozymes in enzyme mimicking processes and prudent bio-catalytic efficiency - Covers the latest methods and procedures involved in enzyme-incorporated nanomaterials
Enzymes: Novel Biotechnological Approaches for the Food Industry provides an in-depth background of the most up-to-date scientific research and information related to food biotechnology and offers a wide spectrum of biological applications. This book addresses novel biotechnological approaches for the use of enzymes in the food industry to help readers understand the potential uses of biological applications to advance research. This is an essential resource to researchers and both undergraduate and graduate students in the biotechnological industries. - Provides fundamental and rigorous scientific information on enzymes - Illustrates enzymes as tools to achieve value and quality to a product, either in vitro or in vivo - Presents the most updated knowledge in the area of food biotechnology - Demonstrates novel horizons and potential for the use of enzymes in industrial applications
The integration of nanotechnology with biomaterials, diagnostic tools, analytical equipment, physiotherapy kits, and drug delivery agents has resulted in nanotherapeutics illustrated as a class of medicine with potential of research and development. This book illustrates synthesis, properties, and applications of nanotherapeutics in various healthcare-related issues including treatment of cancer, Alzheimer’s disease, targeted drug delivery, anti-HIV-1 nanotherapeutics, antibacterial/antiviral agents, skin therapy, and hyperthermia. Features: Consolidates different aspects of nanoparticles such as synthesis and types of nanotherapeutics in a detailed manner Presents categorical classification of nanoparticles as therapeutics Covers the sustainability of nanotherapeutics Reviews fabrication and advancement of all categories of nanotherapeutics Discusses specific applications such as in cancer therapy, skin treatments, and targeted drug delivery This book is aimed at researchers, professionals, and senior undergraduate students in materials and medical science, biomedical engineering, and nanotechnology
Phospholipases in Physiology and Pathology presents a comprehensive overview on the physiology and pathology of phospholipases. This seven-volume set considers the biochemical and molecular mechanisms of normal and abnormal cell function upon dysregulation of phospholipases in different diseases. Volumes cover signal transduction mechanisms, implications in cancer, infectious diseases, neural diseases, cardiovascular diseases and other diseases, implications in inflammation, apoptosis, gene expression and non-coding RNAs, the role of natural and synthetic compounds, and stem cell therapies, nanotechnology-based therapies, and more. Together, these volumes give researchers critical insight on the mechanistic and therapeutic aspects of phospholipases. - Discusses the biochemical and molecular mechanisms of normal and abnormal cell function in different disease processes - Covers a wide range of basic and translational research appropriate for scientists engaged in studying the regulation of phospholipases from interdisciplinary perspectives - Features state-of-the-art chapter contributions from international leaders in the field