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Succession-nothing in plant, community, or ecosystem ecology has been so elaborated by terminology, so much reviewed, and yet so much the center of controversy. In a general sense, every ecologist uses the concept in teaching and research, but no two ecologists seem to have a unified concept of the details of succession. The word was used by Thoreau to describe, from a naturalist's point of view, the general changes observed during the transition of an old field to a forest. As data accumulated, a lengthy taxonomy of succession developed around early twentieth century ecologists such as Cooper, Clements, and Gleason. Now, nearer the end of the century, and after much discussion concerning the nature of vegetation communities, where do ecologists stand with respect to knowledge of ecological succession? The intent of this book is not to rehash classic philosophies of succession that have emerged through the past several decades of study, but to provide a forum for ecologists to present their current research and present-day interpretation of data. To this end, we brought together a group of scientists currently studying terrestrial plant succession, who represent research experience in a broad spectrum of different ecosystem types. The results of that meeting led to this book, which presents to the reader a unique summary of contemporary research on forest succession.
This new Encyclopedia of Coastal Science stands as the latest authoritative source in the field of coastal studies, making it the standard reference work for specialists and the interested lay person. Unique in its interdisciplinary approach. This Encyclopedia features contributions by 245 well-known international specialists in their respective fields and is abundantly illustrated with line-drawings and photographs. Not only does this volume offer an extensive number of entries, it also includes various appendices, an illustrated glossary of coastal morphology and extensive bibliographic listings.
This book contains most updated information on synthesis of magnetic nanohybrids, their physio-chemical properties, and key biological applications. It highlights the complexity of nanoheterostructures, especially magnetic metal oxides, ferrites and doped magnetic nanomaterials, and discusses their potential applications in the early detection, imaging and treatment of cancer. It also covers the toxicity and risk assessment of multifunctional nanomaterials. Providing an overview of magnetic nanoheterostructures, it appeals to a wide audience, from beginners and graduate-level students to experts in academia and industry.
Since the first concepts of gene therapy were formulated, the hemopoietic system has been considered the most natural first target tissue for genetic manipulation. The reasons for this include the fact that a very large number of inherited disorders (including some of the most common disorders, such as the hemoglobinopathies) are disorders of the hemopoietic system, and the large amount of experience in hematopoietic transplantation biology. The consequence of this resulted in the first clinical trial of gene therapy in 1989, where two children suffering from severe combined immune deficiency (ADA-SCID) were transplanted with T-cells express ing adenosine deaminase (the defective enzyme in patients with this disorder). The partial success of this treatment was perhaps responsible for undue optimism among those proposing other gene therapy treatments within the hematopoietic system, and it has since become clear that there are a number of technical and biological difficulties to overcome before hematopoietic gene therapy becomes a mainstream therapeutic strategy. The chapters in this book evaluate the need for gene therapy in the hematopoietic system, discuss how efficient gene transfer and expression can be achieved in the target cells, highlight areas of difficulty to be addressed, and examine a number of potential applications of the gene therapy approach. The book begins with a chapter by Testa and colleagues, discussing the various sources of hematopoietic cells for both transplantation and gene therapy.