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What begins as one woman’s search for her own artistic courage unravels into a stunning look into what jazz music can teach out about our search for the truest version of ourselves. For decades, seasoned players on the scene have spoken in whispered tones about The Blue: a mysterious meeting place for jazz history - a place where ghosts from this music's storied past spring to life for those courageous enough to enter. When Jessie Choi's mentor Jimmy Hightower collapses at a gig and loses consciousness, she finds herself reluctantly pulled back into the jazz scene she abandoned years earlier. In investigating the music and mystery behind Jimmy's comatose state, every thread leads to the same question: is Jimmy somehow trapped in this enigma known as The Blue? In her search to save her teacher, Jessie rubs shoulders with legends, uncovers the secret history of Blue Note Records, and faces her own deepest fears.
“Research is to see what everybody else has seen, and to think what nobody else has thought. ” — Albert Szentgyörgyi Autoimmunity: Methods and Protocols is intended to serve as a ready-to-use guide to establish and interrogate human and animal models of autoimmune diseases. The first chapter, “Pathogenesis and Spectrum of Autoimmunity,” discusses major hypotheses driving this most tantalizing area of research since Paul Ehrlich proposed the concept of autoimmunity in 1900. Considering the great diversity and ever-changing spectrum of autoimmunity, it has not been possible to include models and experimental protocols for each known disorder. Rather, several chapters have been devoted to the most prevalent and complex diseases, such as rheumatoid arthritis, systemic lupus erythematosus, insulin-dependent diabetes mellitus, and multiple sclerosis. The chapters are contributed by laboratories actively using the models presented. Each chapter contains an introductory section that discusses the relevance of the model for a particular disease and for autoimmunity in general. Part I contains methods and protocols to assess immunological and biochemical pathways relevant for disease pathogenesis. Chapters in this section focus on methods to identify susceptibility genes, intercellular signaling via cytokines, intracellular signaling through the T-cell receptor and signal processing via protein kinases, identification and enumeration of autoantigen-specific T cells and autoantibodies, and the dysregulation of apoptosis and its role in modification of self-antigens. Part II contains protocols to establish and assess inflammatory arthritis, systemic lupus erythematosus, myocarditis, thyroiditis, experimental autoimmune encepha- myelitis, insulin-dependent diabetes mellitus, scleroderma, uveitis, and vitiligo.
This book commemorates the work done by Tony Hoare and published under the title Communicating Sequential Processes in the 1978 August issue of the Communications of ACM. The British Computer Society's specialist group Formal Aspects of Computing Science organized a meeting on July 7-8, 2004, in London, to mark the occasion of 25 years of CSP. The 19 carefully reviewed and revised full papers by leading researchers celebrate, reflect upon, and look beyond the first quarter-century of CSP's contributions to computer science. The papers explore the impact of CSP on many areas ranging from semantics and logic, through the design of parallel programming languages to applications varying from distributed software and parallel computing to information security, Web services, and concurrent hardware circuits.
This is the eBook of the printed book and may not include any media, website access codes, or print supplements that may come packaged with the bound book. Advance your everyday proficiency with Access 2016. And earn the credential that proves it! Demonstrate your expertise with Microsoft Access! Designed to help you practice and prepare for Microsoft Office Specialist (MOS): Access 2016 certification, this official Study Guide delivers: • In-depth preparation for each MOS objective • Detailed procedures to help build the skills measured by the exam • Hands-on tasks to practice what you’ve learned • Practice files and sample solutions Sharpen the skills measured by these objectives: • Create and manage databases • Build tables • Create queries • Create forms • Create reports
After fourteen years of bullying, his strong will was forged. Fourteen years later, he would regain his Martial Veins and obtain the Heavenly Treasures, the Heavenly Jade Pendant. From then on, he would rise to greatness. For the sake of his parents, for the sake of the truth, for the sake of his beauties, he had ignited his will to climb to the peak. He had engaged in a fierce struggle with the Heaven's Pride of the Seven Realms, leaving behind one legend after another!
The Earth itself is a remarkable place. It flows with life in every direction, and no one appreciates the joys of life more than Dionisio Sedano - a teenage orphan whose greatest passions include his love of learning, his desire to experience every adventure the world has to offer, and the never-ending joys found in the Land of Eternal Spring. But the natural balance of the world is in peril. The beings responsible for the wellness of our planet were forced to follow the selfish desires of a single, powerful leader, who is willing to once again destroy it all in order to restore that which was taken from nature. What stands between success and failure is a resplendent bird, who may be the Earth's final stand in the greatest ever clash between the Alpha and the Omega.