Download Free Engineering Plasmonic Nanostructures For Multi Dimensional Biosensing With Surface Plasmon Resonance Book in PDF and EPUB Free Download. You can read online Engineering Plasmonic Nanostructures For Multi Dimensional Biosensing With Surface Plasmon Resonance and write the review.

In addition, a new approach for SPR analysis of carbohydrate interactions has been developed with fluorochemistry and calcinated SPR gold film. Fluoroalkysilane was used to provide a monolayer modification of the hydrophobic interface for effective capturing of carbohydrate probes through non-covalent interaction. Molecular recognition with various lectins was investigated by real-time kinetic study. Polydimethylsiloxane (PDMS) channel chips were utilized that enabled parallel analysis for high-throughput detection of carbohydrate-protein interaction with SPR imaging technique. Matrix-free LDI-MS of the calcinated gold film and array is not compromised by the SAM coating, allowing for the development of new SPR-MS on-chip analysis. Finally, a novel label-free biosensing approach based on thin-film transmission interferometry (TTi) has been developed with nanoscale porous anodic alumina (PAA) film. The optical phenomenon of TTi has been successfully confirmed by simulation. Performance of TTi sensing in relation to the structural geometries of PAA nanofilm was studied, providing valuable insights into the optimization of TTi-substrate based on porosity, thickness, and pore diameter to achieve high biosensing sensitivity. This newly developed substrate also provides a convenient platform for biological studies of protein adsorption. As a surface-sensitive label-free detection, TTi shows a great potential to be incorporated into the ongoing on-chip SPR-MS biosensor development for achieving higher level of research possibilities.
Plasmonic nanoparticles (PNs) have unique optical properties that make them particularly attractive for biosensing applications. These properties arise due the localized surface plasmon resonance (LSPR) on their surface which occurs upon light excitation that is typically in the visible region of the electromagnetic spectrum. The absorbing and scattering properties of PNs are derived from the LSPR and are tunable based on the nanoparticle shape, size, and local dielectric environment. Furthermore, the LSPR on PNs enables fluorophores in close proximity (
The fabrication of plasmonic nanostructures with sub-10 nm gaps supporting extremely large electric field enhancement (hot-spot) has attained great interest over the past years, especially in ultra-sensing applications. The "hot-spot" concept has been successfully implemented in surface-enhanced Raman spectroscopy (SERS) through the extensive exploitation of localized surface plasmon resonances. However, the detection of analyte molecules at ultra-low concentrations, id est, down to the single/few molecule level, still remains an open challenge due to the poor localization of analyte molecules onto the hot-spot region. On the other hand, three-dimensional nanostructures with multiple branches have been recently introduced, demonstrating breakthrough performances in hot-spot-mediated ultra-sensitive detection. Multi-branched nanostructures support high hot-spot densities with large electromagnetic (EM) fields at the interparticle separations and sharp edges, and exhibit excellent uniformity and morphological homogeneity, thus allowing for unprecedented reproducibility in the SERS signals. 3D multi-branched nanostructures with various configurations are engineered for high hot-spot density SERS substrates, showing an enhancement factor of 1011 with a low detection limit of 1 fM. In this view, multi-branched nanostructures assume enormous importance in analyte detection at ultra-low concentrations, where the superior hot-spot density can promote the identification of probe molecules with increased contrast and spatial resolution.
Plasmonics is a rapidly developing field that combines fundamental research and applications ranging from areas such as physics to engineering, chemistry, biology, medicine, food sciences, and the environmental sciences. Plasmonics appeared in the 1950s with the discovery of surface plasmon polaritons. Plasmonics then went through a novel propulsion in the mid-1970s, when surface-enhanced Raman scattering was discovered. Nevertheless, it is in this last decade that a very significant explosion of plasmonics and its applications has occurred. Thus, this book provides a snapshot of the current advances in these various areas of plasmonics and its applications, such as engineering, sensing, surface-enhanced fluorescence, catalysis, and photovoltaic devices.
This book contains 35 review articles on nanoscience and nanotechnology that were first published in Nature Nanotechnology, Nature Materials and a number of other Nature journals. The articles are all written by leading authorities in their field and cover a wide range of areas in nanoscience and technology, from basic research (such as single-molecule devices and new materials) through to applications (in, for example, nanomedicine and data storage).
This book is a compendium of the finest research in nanoplasmonic sensing done around the world in the last decade. It describes basic theoretical considerations of nanoplasmons in the dielectric environment, gives examples of the multitude of applications of nanoplasmonics in biomedical and chemical sensing, and provides an overview of future trends in optical and non-optical nanoplasmonic sensing. Specifically, readers are guided through both the fundamentals and the latest research in the two major fields nanoplasmonic sensing is applied to – bio- and chemo-sensing – then given the state-of-the-art recipes used in nanoplasmonic sensing research.
Surface plasmon resonance (SPR) sensing for quantitative analysis of chemical reactions and biological interactions has become one of the most promising applications of plasmonics. This thesis focuses on performance analysis for plasmonic sensors and implementation of plamonic optical sensors with novel nanofabrication techniques. A universal performance analysis model is established for general two-dimensional plasmonic sensors. This model is based on the fundamental facts of surface plasmon theory. The sensitivity only depends on excitation light wavelength as well as dielectric properties of metal and dielectrics. The expression involves no structure-specified parameters, which validates this formula in broad cases of periodic, quasiperiodic and aperiodic nanostructures. Further analysis reveals the intrinsic relationship between plamonic sensor performance and essential physics of surface plasmon. The analytical results are compared to the sensitivities of previously reported plasmonic sensors in the field. This universal model is a promising qualification criterion for plasmonic sensors. Plasmonic optical sensors are engineered into high-performance on-chip sensors, plasmonic optical fibers and freestanding nanomembranes. (1) Periodic nanohole arrays are patterned on chip by a simple and robust template-transfer approach. A spectral analysis approach is also developed for improving the sensor performance. This sensor is applied to demonstrate the on-chip detection of cardiac troponin-I. (2) Plasmonic optical fibers are constructed by transferring periodic metal nanostructures from patterned templates onto endfaces of optical fibers using an epoxy adhesive. Patterned metal structures are generally extended from nanohole arrays to nanoslit arrays. A special plasmonic fiber is designed to simultaneously implement multimode refractive index sensing with remarkably narrow linewidth and high figure of merit. A real-time immunoassay relying on plasmonic fiber is demonstrated. Plasmonic optical fibers also take advantages of consistent optical responses, excellent stability during fiber bending and capability of spectrum filtering. (3) Large-area freestanding metal nanomembranes are implemented using a novel fabrication approach. The formed transferrable membranes feature high-quality and uniform periodic nanohole arrays. The freestanding nanomembranes exhibit remarkably higher transmission intensity in comparison to the nanohole arrays with same features on the substrate. These three modalities of plasmonic sensors possess different applicability to fulfill various plasmonic sensing tasks in respective scenarios.
Current developments in optical technologies are being directed toward nanoscale devices with subwavelength dimensions, in which photons are manipulated on the nanoscale. Although light is clearly the fastest means to send information to and from the nanoscale, there is a fundamental incompatibility between light at the microscale and devices and processes at the nanoscale. Nanostructured metals which support surface plasmon modes can concentrate electromagnetic (EM) fields to a small fraction of a wavelength while enhancing local field strengths by several orders of magnitude. For this reason, plasmonic nanostructures can serve as optical couplers across the nano–micro interface: metal–dielectric and metal–semiconductor nanostructures can act as optical nanoantennae and enhance light matter coupling in nanoscale devices. This book describes how one can fully integrate plasmonic nanostructures into dielectric, semiconductor, and molecular photonic devices, for guiding photons across the nano–micro interface and for detecting molecules with unsurpassed sensitivity. ·Nanophotonics and Nanoplasmonics·Metamaterials and negative-index materials·Plasmon-enhanced sensing and spectroscopy·Imaging and sensing on the nanoscale·Metal Optics
This book highlights cutting-edge research in surface plasmons, discussing the different types and providing a comprehensive overview of their applications. Surface plasmons (SPs) receive special attention in nanoscience and nanotechnology due to their unique optical, electrical, magnetic, and catalytic properties when operating at the nanoscale. The excitation of SPs in metal nanostructures enables the manipulation of light beyond the diffraction limit, which can be utilized for enhancing and tailoring light-matter interactions and developing ultra-compact high-performance nanophotonic devices for various applications. With clear and understandable illustrations, tables, and descriptions, this book provides physicists, materials scientists, chemists, engineers, and their students with a fundamental understanding of surface plasmons and device applications as a basis for future developments.