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With cardiovascular diseases being one of the main causes of death in the world, quantitative modeling, assessment and monitoring of the cardiovascular control system plays a critical role in bringing important breakthroughs to cardiovascular care. Quantification of cardiovascular physiology and its control dynamics from physiological recordings and by use of mathematical models and algorithms has been proved to be of important value in understanding the causes of cardiovascular diseases and assisting the prognostic or diagnostic process. Nowadays, development of new recording technologies (e.g., electrophysiology, imaging, ultrasound, etc) has enabled us to improve and expand acquisition of a wide spectrum of physiological measures related to cardiovascular control. An emerging challenge is to process and interpret such increasing amount of information by using state-of-the-art approaches in systems modeling, estimation and control, and signal processing, which would lead to further insightful scientific findings. In particular, multi-disciplinary engineering-empowered approaches of studying cardiovascular systems would greatly deepen our understanding of cardiovascular functions (e.g., heart rate variability, baroreflex sensitivity) and autonomic control, as it would also improve the knowledge about heart pathology, cardiovascular rehabilitation and therapy. Meanwhile, developing cardiovascular biomedical devices or heart-machine interface for either clinical monitoring or rehabilitation purpose is of greater and greater interest for both scientific advancement and potential medical benefits. This Research Topic will bring together established experts whose areas of research cover a wide range of studies and applications. Contributions include but are not limited to state-of-the-art modeling methodologies, algorithmic development in signal processing and estimation, as well as applications in cardiovascular rehabilitation, and clinical monitoring. The Research Topic will consider both invited reviews and original research.
In the past few years Biomedical Engineering has received a great deal of attention as one of the emerging technologies in the last decade and for years to come, as witnessed by the many books, conferences, and their proceedings. Media attention, due to the applications-oriented advances in Biomedical Engineering, has also increased. Much of the excitement comes from the fact that technology is rapidly changing and new technological adventures become available and feasible every day. For many years the physical sciences contributed to medicine in the form of expertise in radiology and slow but steady contributions to other more diverse fields, such as computers in surgery and diagnosis, neurology, cardiology, vision and visual prosthesis, audition and hearing aids, artificial limbs, biomechanics, and biomaterials. The list goes on. It is therefore hard for a person unfamiliar with a subject to separate the substance from the hype. Many of the applications of Biomedical Engineering are rather complex and difficult to understand even by the not so novice in the field. Much of the hardware and software tools available are either too simplistic to be useful or too complicated to be understood and applied. In addition, the lack of a common language between engineers and computer scientists and their counterparts in the medical profession, sometimes becomes a barrier to progress.
Cyber–Physical–Human Systems A comprehensive edited volume exploring the latest in the interactions between cyber–physical systems and humans In Cyber–Physical–Human Systems: Fundamentals and Applications, a team of distinguished researchers delivers a robust and up-to-date volume of contributions from leading researchers on Cyber–Physical–Human Systems, an emerging class of systems with increased interactions between cyber–physical, and human systems communicating with each other at various levels across space and time, so as to achieve desired performance related to human welfare, efficiency, and sustainability. The editors have focused on papers that address the power of emerging CPHS disciplines, all of which feature humans as an active component during cyber and physical interactions. Articles that span fundamental concepts and methods to various applications in engineering sectors of transportation, robotics, and healthcare and general socio-technical systems such as smart cities are featured. Together, these articles address challenges and opportunities that arise due to the emerging interactions between cyber–physical systems and humans, allowing readers to appreciate the intersection of cyber–physical system research and human behavior in large-scale systems. In the book, readers will also find: A thorough introduction to the fundamentals of cyber–physical–human systems In-depth discussions of cyber–physical–human systems with applications in transportation, robotics, and healthcare A comprehensive treatment of socio-technical systems, including social networks and smart cities Perfect for cyber–physical systems researchers, academics, and graduate students, Cyber–Physical–Human Systems: Fundamentals and Applications will also earn a place in the libraries of research and development professionals working in industry and government agencies.
Pervasive Cardiac and Respiratory Monitoring Devices: Model-Based Design is the first book to combine biomedical instrumentation and model-based design. As the scope is limited to cardiac and respiratory devices only, this book offers more depth of information on these devices; focusing in on signals used for home monitoring and offering additional analysis of these devices. The author offers an insight into new industry and research trends, including advances in contactless monitoring of breathing and heart rate. Each chapter presents a section on current trends. As instrumentation as a field is becoming increasingly smart, basic signal processing is also discussed. Real case-studies for each modelling approach are used, primarily covering blood pressure, ECG and radar-based devices. This title is ideal for teaching and supporting learning as it is written in an accessible style and a solutions manual for the problem sets is provided. It will be useful to 4th year undergraduate students, graduate/masters/PhD students, early career researchers and professionals working on an interdisciplinary project; as it introduces the field and provides real world applications. For engineers this book solves the problem of how to assess and calibrate a medical device to ensure the data collected is trustworthy. For students, this book allows for trying concepts and circuits via simulations and learning modeling techniques. Students will learn concepts from this book and be ready to design bioinstrumentations devices based on specifications/requirements. - Focuses on model-based design using Simscape/MATLAB; learn how to design a system and how to evaluate how different choices affect the output of the system - Covers pervasive monitoring: shows how to design optimal solutions for pervasive and personalized healthcare monitoring - Explores uncertainty and sensitivity analysis; understand your model better
Divided roughly into two sections, this book provides a brief history of the development of ECG along with heart rate variability (HRV) algorithms and the engineering innovations over the last decade in this area. It reviews clinical research, presents an overview of the clinical field, and the importance of heart rate variability in diagnosis. The book then discusses the use of particular ECG and HRV algorithms in the context of clinical applications.
A guide to common control principles and how they are used to characterize a variety of physiological mechanisms The second edition of Physiological Control Systems offers an updated and comprehensive resource that reviews the fundamental concepts of classical control theory and how engineering methodology can be applied to obtain a quantitative understanding of physiological systems. The revised text also contains more advanced topics that feature applications to physiology of nonlinear dynamics, parameter estimation methods, and adaptive estimation and control. The author—a noted expert in the field—includes a wealth of worked examples that illustrate key concepts and methodology and offers in-depth analyses of selected physiological control models that highlight the topics presented. The author discusses the most noteworthy developments in system identification, optimal control, and nonlinear dynamical analysis and targets recent bioengineering advances. Designed to be a practical resource, the text includes guided experiments with simulation models (using Simulink/Matlab). Physiological Control Systems focuses on common control principles that can be used to characterize a broad variety of physiological mechanisms. This revised resource: Offers new sections that explore identification of nonlinear and time-varying systems, and provide the background for understanding the link between continuous-time and discrete-time dynamic models Presents helpful, hands-on experimentation with computer simulation models Contains fully updated problems and exercises at the end of each chapter Written for biomedical engineering students and biomedical scientists, Physiological Control Systems, offers an updated edition of this key resource for understanding classical control theory and its application to physiological systems. It also contains contemporary topics and methodologies that shape bioengineering research today.
These proceedings of the World Congress 2006, the fourteenth conference in this series, offer a strong scientific program covering a wide range of issues and challenges which are currently present in Medical physics and Biomedical Engineering. About 2,500 peer reviewed contributions are presented in a six volume book, comprising 25 tracks, joint conferences and symposia, and including invited contributions from well known researchers in this field.
It is with great pleasure that we present to you a collection of over 200 high quality technical papers from more than 10 countries that were presented at the Biomed 2008. The papers cover almost every aspect of Biomedical Engineering, from artificial intelligence to biomechanics, from medical informatics to tissue engineering. They also come from almost all parts of the globe, from America to Europe, from the Middle East to the Asia-Pacific. This set of papers presents to you the current research work being carried out in various disciplines of Biomedical En- neering, including new and innovative researches in emerging areas. As the organizers of Biomed 2008, we are very proud to be able to come-up with this publication. We owe the success to many individuals who worked very hard to achieve this: members of the Technical Committee, the Editors, and the Inter- tional Advisory Committee. We would like to take this opportunity to record our thanks and appreciation to each and every one of them. We are pretty sure that you will find many of the papers illuminating and useful for your own research and study. We hope that you will enjoy yourselves going through them as much as we had enjoyed compiling them into the proceedings. Assoc. Prof. Dr. Noor Azuan Abu Osman Chairperson, Organising Committee, Biomed 2008
Catheter ablation is a major treatment for atrial tachycardias. Hereby, the precise monitoring of the lesion formation is an important success factor. This book presents computational, wet-lab, and clinical studies with the aim of evaluating the signal characteristics of the intracardiac electrograms (IEGMs) recorded around ablation lesions from different perspectives. The detailed analysis of the IEGMs can optimize the description of durable and complex lesions during the ablation procedure.
The guest editors of this eBook have accepted 10 very high-quality submissions for inclusion in a special issue of Frontiers in Physiology. The key difference between this eBook and contemporary fetal physiology related literature is that this Research Topic summarizes additional insights into the physiological link between physiologically understandable mathematical indices of fetal signals and the developing cardiovascular functions in fetal health and compromises. This book should be of considerable help to researchers, professionals in fetal monitoring device industries, academics, and graduate students from a wide range of disciplines. The text provides a comprehensive account of recent research in this emerging field and we anticipate that the concepts presented here will generate further research in this field.