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The Atlas of Endoscopic Ultrasonography provides readers with a large collection of excellent images obtained from both diagnostic and therapeutic procedures. The Atlas includes a DVD which will be an invaluable addition to the library of trainee and practising gastroenterologists with video clips and searchable database of images. Together the book and DVD offer a first class collection of images to give a highly integrated introduction to endoscopic ultrasonography. The Atlas is an ideal companion to Dr Gress et al’s Endoscopic Ultrasonography, Second Edition.
This book provides a comprehensive and up-to-date overview of current endoscopic ultrasound use in all aspects of pancreatology, from diagnosis to therapy, i.e., from tissue acquisition, with standard fine-needle aspiration and the newer biopsy needles, to less invasive techniques such as contrast-enhanced ultrasound and elastography. It also covers novel therapeutic strategies, with a particular focus on ablative treatments and lumen-apposing stents, and describes techniques developed by the editors, in particular combined celiac plexus neurolysis with pancreatic tumor ethanol ablation and elastography-guided fine-needle aspiration. All topics are developed by pursuing an evidence-based approach and several recent meta-analyses, the majority of which were published by the authors. Due to several recent advances in the field, endoscopic ultrasound has taken on a pivotal role in the diagnosis, staging, and treatment of pancreatic lesions; as such, the present volume offers an invaluable tool for staying abreast of the state-of-the-art in this field.
Clinical Pancreatology Since the book Clinical Pancreatology for Practising Gastroenterologists and Surgeons was first published sixteen years ago, the knowledge and clinical management of pancreatic diseases have developed markedly. Thanks to the development of the translational research and the from bench to bedside concept, much progress from the lab has been applied to clinical practice. In addition, several highly relevant clinical trials published over the last years have resulted in the update and optimisation of clinical guidelines. A new and validated classification of severity and complications of acute pancreatitis is firmly rooted in clinical practice and has been the basis for the development of minimally invasive approaches to pancreatic necrosis. The etiopathogenic knowledge of chronic pancreatitis and other pancreatopaties, like that associated with diabetes mellitus, has developed significantly. Especially important has been the development of the field of cystic pancreatic tumours, which has been reflected in the publication of several guidelines and consensus reports over the last few years. Most research efforts have focused on pancreatic cancer, which have led and will further lead to a significant increase in the therapeutic armamentarium against this devastating disease. Finally, many newly published studies have changed the concept, causes, clinical relevance, diagnosis and treatment of exocrine pancreatic insufficiency. This new edition of Clinical Pancreatology for Practising Gastroenterologists and Surgeons has enjoyed the collaboration of the world’s leading experts in each of the areas of clinical pancreatology with the aim of facilitating gastroenterologists, surgeons, oncologists, internists, nutritionists, diabetologists, paediatricians, radiologists, pathologists and other specialists in their decision making when facing patients with pancreatic diseases in their daily clinical practice. All in all, this book supplies an indispensable update of the relevant aspects of clinical pancreatology.
The reference text for all those practicing diagnostic and therapeutic pediatric endoscopy – trainees, trainers, specialist endoscopists, gastroenterologists and hepatologists alike. Practical Pediatric Gastrointestinal Endoscopy, 3rd Edition provides a comprehensive and up-to-date exploration for the performance of endoscopy in infants, children and young adults. Written in the form of a complete "how to" manual and filled with step-by-step instructions, this book seeks to bring newcomers to the field of pediatric gastrointestinal endoscopy quickly up to speed. The book is also highly useful for experienced specialist endoscopists and gastroenterologists to brush up on best practice in standard techniques and explore advanced topics in the field. Practical Pediatric Gastrointestinal Endoscopy highlights the substantial and important differences between performing an endoscopy on a mature adult and performing one in a pediatric patient. The differences discussed include: GI pathology Subtleties of diagnostic technique specific to children Application of therapeutic endoscopy to specifically pediatric scenarios Anesthesia and sedation Training and skill maintenance Sophisticated endoscopic techniques adapted from adult endoscopy to children and those techniques specifically orientated to problems and diseases mainly encountered in childhood. This guide is becoming an essential companion for those of us providing diagnostic and therapeutic endoscopy for children in the world today and opens the door to future possibilities in this ever-evolving field.
This book is oriented toward clinical studies in the field of endoscopic ultrasound. Due to the advancement in technology, resolution and development of accessory tools, the applications of endoscopic ultrasound have been widely extended. This book covers from usual to special applications of endoscopic ultrasound in various specialties. I hope this book can serve as a tiny telescope that shows how the techniques of endoscopic ultrasound can be used in various parts of the body.
Covering the full spectrum of endoscopic ultrasound, Endosonography, 4th Edition, by Drs. Robert Hawes, Paul Fockens, and Shyam Varadarajulu, is a comprehensive, one-stop resource for mastering both diagnostic and therapeutic EUS procedures. Leading global authorities guide you step by step through both introductory and advanced techniques, covering everything from interpretation and accurate diagnosis to treatment recommendations. High-quality images and an easy-to-navigate format make this updated reference a must-have for both beginning and experienced endosonographers. Provides practical information on establishing an endoscopic practice, from what equipment to buy to providing effective cytopathology services. Employs a user-friendly templated format to cover all topics from basic applications to advanced interventions, with procedures organized by body system. Features completed updated content throughout, including new sections on high-intensity focused ultrasound, through-the-needle biopsy, benign pancreatic masses, and gastro-jejunostomy. Includes perspectives from new contributors who provide global experience and knowledge. Contains new and enhanced illustrations that correlate with high-quality endoscopic images. Teaches clinically relevant techniques through dozens of new how-to videos. Covers cutting-edge techniques for performing therapeutic interventions, such as drainage of pancreatic pseudocysts and EUS-guided anti-tumor therapy, as well as fine needle aspiration (FNA) procedures. Expert ConsultTM eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices.
Drug repurposing is the development of existing drugs for new uses: given that 9 in 10 drugs that enter drug development are never marketed and therefore represent wasted effort, it is an attractive as well as inherently more efficient process. Three repurposed drugs can be brought to market for the same cost as one new chemical entity; and they can also be identified more quickly, an important benefit for patients whose diseases are progressing faster than therapeutic innovation. But repurposing also requires a fresh look at configuring pharmaceutical R&D, considering clinical, regulatory and patent issues much earlier than would otherwise be the case; a holistic gedanken experiment almost needs to be undertaken at the very start of any repurposing development. In addition to new ways of thinking, the discovery of repurposing opportunities can take advantage of artificial intelligence techniques to match the perfect new use for an existing drug. And while repurposing of medicines has been in the mind of every doctor since Hypocrates, modern clinical practice will simply have to adapt to new repurposing techniques in an age where the number of known diseases is increasing much faster than the healthcare dollars available.
This book provides an up-to-date review of therapeutic EUS with an equal focus on technical descriptions with ample endoscopic images/video clips by world experts and the scientific evidence behind the described techniques. The book provides an overview of the field in a structured manner, starting with general topics on equipment and service development and extending to the fields of EUS-guided drainage, anti-tumor therapies, and other specific EUS-guided interventional treatments. Therapeutic Endoscopic Ultrasound is a key resource for endoscopists, gastroenterologists, surgeons, and GI oncologists.
This volume presents the technical and cultural state of the art of two of the riskiest, most complex and operator-dependent digestive operative techniques: endoscopic retrograde cholangiopancreatography (ERCP) and endoscopic ultrasonography (EUS). The authors compare old and new techniques, shedding light on the most recent and innovative scientific findings, including those in the field of anatomic pathology and molecular biology considered relevant for the analysis of tissue samples collected during EUS. In view of the technical difficulties specific to these techniques, the book also offers access to online-videos and numerous images, making it a valuable resource both for physicians approaching these techniques for the first time as well as for those already using them. Organized into 7 sections, it describes in detail all techniques related to ERCP/EUS, together with any specific technical equipment required. It also presents a new paradigm based on the latest results in the areas of prevention, diagnosis and management of the most common complications. Clinical outcomes presented in international literature, as well as algorithms – both based on scientific evidence and expert findings – are illustrated and compared to alternative treatments.
This unique book is the first to focus on diagnostic and therapeutic endoscopy in gastrointestinal and pancreatico-biliary diseases. It provides an in-depth overview of the state of the art in diagnostic and therapeutic endoscopy of both the digestive tract and the pancreatico-biliary ductal system, and documents the latest innovations in the field. The first part of the book addresses advanced diagnostic and therapeutic endoscopy of the digestive tract, discussing bariatric endoscopic surgery, and the treatment of neoplasia and precancerous lesions of the upper and lower GI tract, motor disorders, GERD, strictures, fistulae and bleeding. The second part of the book is explores ERCP and EUS procedures, covering the diagnosis and therapy of biliary ductal system and pancreatic diseases. Each chapter includes an abundance of color images that document in detail the devices, operative techniques and outcomes. Written by leading internationally renowned experts, the book is a valuable resource for both specialists and residents in gastroenterology and surgery.