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This book provides the latest information on diagnosis and treatment strategies for colorectal T1(SM) carcinoma including endoscopic resection, and pathologic diagnosis and treatment following resection. Due to constant advances, the curative phase after the endoscopic resection of carcinomas has extended, shifting the endpoints of diagnosis and treatment strategies. This book thoroughly summarizes the latest findings, explained with the help of abundant color figures, and will serve as a basis for further discussions and advances in this field. Endoscopic Management of Colorectal T1(SM) Carcinoma offers a valuable resource for colonoscopists, colorectal surgeons, and pathologists at all levels. The readers will discover diverse perspectives, provided by the contributing authors, and extensive discussions that are analyzed from Asian perspectives, which often differ from those found in Western texts.
There have been many advances in the diagnosis and treatment of cancer, but it is still a feared disease with a lot of work left to be done. The importance of gastrointestinal cancer as a frequently occurring disease goes without saying. It accounts for half of human cancer cases but differs from other forms of cancer. Complete prevention is possible through proper treatment of precancerous lesions. There is still no comprehensive book about prevention, early diagnosis, and proper treatment of precancerous lesions and new developed diagnostic modality, and treatment such as endoscopic treatment and minimal invasive surgery and chemotherapy and immunotherapy. Also, this book will contain conservative treatment methods for patients suffering from diverse complications. There will be plentiful clinical cases including endoscopic findings, radiologic images, pathology and treatment outcome in this book. For these reasons, this book will give very valuable information to many gastroenterologists, oncologists , surgeons and general physicians.
This book is a comprehensive reference work on the multidisciplinary team (MDT) management of colorectal cancer (CRC) patients that will meet the needs of all members of CRC MDTs and those training in the field. Important, up-to-date knowledge is provided on organization of MDTs, early intervention, surgery, oncology, imaging, pathology, and palliation, with special focus on controversies. This second edition has been thoroughly revised. It includes an entirely new section on the principles of treatment of significant polyps and early cancers and a total of 14 new chapters, including one on the early integration of palliative care. Every effort has been made to ensure that each specialty-specific chapter will be approachable for all team members, thereby facilitating an effective interdisciplinary approach to teamwork. The authors are leading European doctors and scientists who have influenced the development of the MDT concept as well as other aspects of individualized treatment of CRC patients.
This book presents state of the art knowledge and guidance on the use of therapeutic colonoscopy for all of the usual indications, including hemostasis for colorectal bleeding, resection of benign and malignant lesions, and decompression and recanalization of obstructed bowel. Technical aspects are covered in detail, with advice on indications and instrumentation and provision of tips and tricks of proven practical value. With respect to polypectomy, separate chapters focus on technique for pedunculated polyps and the choice between endoscopic piecemeal mucosal resection and endoscopic submucosal dissection for large sessile polyps. The closing chapter looks to the future of therapeutic colonoscopy. The clearly written text is supported by numerous helpful illustrations. Over the years, technological developments have markedly increased the therapeutic, as opposed to the diagnostic, role of endoscopy. This book will be an invaluable aid in clinical practice for all who are involved in the performance of therapeutic colonoscopy.
Covers all aspects of gastrointestinal and liver malignancies (epidemiology, pathophysiology, screening where appropriate, symptoms and clinical signs, diagnostic studies, staging and classification, treatment, prognosis, follow-up, future perspectives). The text is addressed to those involved in the multidisciplinary approach to the gastrointestinal cancer patient (gastroenterologists, medical oncologists, radiation therapists, surgeons, interventional radiologists, pathologists, nurses, and physicians-in-training). The book provides in-depth information, illustrated by numerous color/black-and-white pictures. Selective reading for a quick reference is made possible by introducing text elements such as summaries, tables, listing and treatment algorithms.
This book provides a comprehensive and up-to-date overview of current polypectomy techniques and describes new perspectives in the field. A wide variety of topics are covered, including classification of colon polyps, established polypectomy techniques and related controversies, advanced endoscopic resection, endoscopic submucosal dissection, the use of submucosal injection solutions, management of complications, management of anticoagulant and antiplatelet medications, and post-polypectomy endoscopic surveillance. Information is also provided on a novel risk calculation score for adenoma recurrence after polypectomy, developed by the editors of the book and their colleagues. In acquainting readers with the state of the art in the field, Colon Polypectomy will serve as a valuable reference and practical tool for all who perform the procedure, which is of ever-increasing importance given the recent success of colon cancer screening campaigns in leading to earlier detection of colon polyps.
Everything clinicians need to know about diagnosing and treating digestive tract and liver disorders Striking the perfect balance between comprehensiveness and ease of use, this popular entry in the CURRENT series delivers high-yield coverage of the entire spectrum of gastroenterology and hepatology in a streamlined, consistent presentation. Edited by three expert physicians from Harvard Medical School, the third edition has been updated to include coverage of the latest clinical issues, advances, and developments in the field, and is enhanced by an important new chapter on C. difficile bacterial infections. CURRENT Diagnosis & Treatment Gastroenterology, Hepatology, and Endoscopy features bulleted lists that deliver instant guidance on identifying and treating both common and rare digestive disorders, numerous tables that encapsulate must-know information, and more than 60-full-color radiographic and endoscopic images of GI disorders. This trusted text is known world-wide for its thorough coverage of procedures and techniques in endoscopy and treating various liver disorders. Market: Internal medicine residents (23,000), general internists (77,000), family medicine residents (8,000), gastroenterologists (12,000/USA), international gastroenterologists, and physician assistants (50,000) Includes key information from related fields, including GI surgery, liver transplantation, bariatric surgery, inflammatory bowel disease, and motility disorder Norton J. Greenberger, MD (Boston, MA) is a Senior Attending Physician and Clinical Professor of Medicine at Harvard Medical School. Dr. Greenberger is a past President of the American Gastroenterological Association, the American College of Physicians, the Central Society for Clinical Research and the Association of Professors of Medicine. He is the author or co-author of more than 230 publications including chapters in major medical texts. Richard S. Blumberg, MD (Boston, MA) is Professor of Medicine, Harvard Medical School Chief, Division of Gastroenterology, Hepatology and Endoscopy at Brigham and Women's Hospital. Robert Burakoff, MD, MPH (Boston, MA) is Associate Professor of Medicine, Harvard Medical School Clinical Chief of Gastroenterology, Division of Gastroenterology, Hepatology and Endoscopy at Brigham and Women's Hospital.
Everything clinicians must know to diagnose and treat digestive tract and liver disorders in a streamlined, consistent presentation Great for board review Striking the perfect balance between comprehensiveness and ease of use, CURRENT Diagnosis & Treatment Gastroenterology, Hepatology, & Endoscopy, 2e, is essential for gastroenterologists, general internists, family physicians, and surgeons.The second edition has been updated to reflect the latest advances in diagnostic and therapeutic endoscopy and the content is delivered in an easy-access, find-it-now presentation. High-yield coverage of the entire spectrum of gastroenterology and hepatology, from stomach and esophageal to pancreatic and liver disorders “Essentials of Diagnosis” bulleted lists deliver instant guidance on identifying both common and rare digestive disorders More than 60 full-color radiographic and endoscopic images of GI disorders Numerous tables encapsulate important information Key information from related fields, including GI surgery, and subspecialties such as liver transplantation, bariatric surgery, inflammatory bowel disease, and motility disorder Updated to include the latest therapeutic considerations
Table 1 Cancer is the second most common cause of death in Americans (see www.cdc.gov). Colorectal cancer kills more Incidence and Mortality of the Five Most Common Gastrointestinal Malignancies Americans than any other malignancy except for lung cancer. The incidences and mortalities of the major gastrointestinal a a Site Incidence Mortality (GI) malignancies are shown in Table 1. Taken as a group, the five most common GI malignancies account for more cancers Colorectum 53.9 21.6 and more cancer deaths than for any other site. Pancreas 11.1 10.6 Stomach 9.1 4.9 Flexible endoscopy has given physicians unprecedented Liver/intrahepatic bile ducts 6.2 4.4 access to the GI tract. The ability to endoscopically visu- Esophagus 4.5 4.3 alize, biopsy, and apply therapy has had implications for the management of all the major GI malignancies. Accepted Data from SEER database 1992–2002 (www.seer.cancer.gov). applications of endoscopy range from detection of mal- a Per 100,000.
This book is a comprehensive understanding of the evolution of pre-malignant disease, emphasizing common themes in the field, including stem cell biology and histologic modes of cancer progression between the distal esophagus and stomach. Its sixteen chapters discuss metaplastic tissue change in the upper GI, clonalexpansion of early neoplasia, stem cell dynamics in experimental models, pathology of early esophageal squamous cell carcinoma, therapeutic modalities for esophageal squamous cell carcinoma, pathology of Barrett’s esophagus, screening, early detection and novel diagnostic tools for Barrett's esophagus, clonal evolution of Barrett’s esophagus, endoscopic therapeutic modalities of early esophageal cancer, pathology of early gastric cancer, and experimental models for gastric cancer. Stem Cells, Pre-neoplasia and Early Cancer of the Upper Gastrointestinal Tract is an integrative text on both the current state of translational research on every cancer development of the upper gastrointestinal tract as well as on novel clinical diagnostic and therapeutic modalities. It highlights a rapidly growing field within cancer research and is essential reading for oncologists, biochemists and advanced graduate students alike. Springer’s Advances in Experimental Medicine and Biology series presents multidisciplinary and dynamic findings in the broad fields of experimental medicine and biology. The wide variety in topics it presents offers readers multiple perspectives on a variety of disciplines including neuroscience, microbiology, immunology, biochemistry, biomedical engineering and cancer research.