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At last, the long anticipated second edition of the highly successful Encyclopedia of Reagents for Organic Synthesis (EROS) is publishing in print in March 2009. With its wealth of valuable information, excellent editorial leadership and methodical classification, EROS has become the authoritative reference source on reagents and catalysts. This makes EROS vital reading for everybody working in organic synthesis. It has wide appeal, with relevance not only to Organic Chemists, but also to Inorganic, Physical and Analytical Chemists, Materials Scientists, Chemical Engineers, Biochemists, Medicinal and Pharmaceutical Chemists and Pharmacologists. In short, it is an essential product for all academic and industrial chemistry laboratories and libraries. COMPREHENSIVE With its 50,000 reactions and 4,111 reagents, Encyclopedia of Reagents for Organic Synthesis offers readers a substantial wealth of information. Each entry contains, where available: CAS numbers InChI and InChIKeys Alternative names and structures Details on availability and physical properties, including solubility, form in which it’s supplied, purification methods, form obtainable in purification and preparation methods Extensive reviews Examples of transformations for each reagent with reaction schemes Comparison of one agent’s specific properties with those of others capable of equivalent chemistry, together with reaction schemes Stereo-, regio-, and enantio-control properties Required precautions for working with the reagent The various uses and characteristics of each reagent with illustrative examples Related literature METHODICAL Encyclopedia of Reagents for Organic Synthesis has been designed and developed by chemists for chemists. It makes it as easy as possible for users to find the most suitable reagents for performing particular reactions. Reagents are arranged in A to Z format while each reagent entry is presented in a uniform style so that the user is provided with a recognizable format and structure. New in the second edition of Encyclopedia of Reagents for Organic Synthesis: Over 1,000 new reagents Over 620 updated reagents retaining the original text and references whilst adding additional up-to-date information New types of reagents and catalysts In addition to CAS numbers each article now also includes InChI and InChIKeys A standard citation style in the reference list for each reagent An author index
The Handbook is a compilation of 99 articles on diverse reagents and catalysts that describe the synthesis of heteroarenes, the building blocks of a wide range of chemicals used in pharma and chemical industries. Articles are selected from the e-EROS database and edited to make sure that it includes only the material relevant to the topic of the book and focus on the synthetic aspects. This makes the articles very focused on the needs of readers wanting information on specific syntheses of specific heteroarenes. In addition, the chemistry of each parent heteroarene is also included to ensure that the reader rapidly finds important information. The Handbook is a part of the Handbook of Reagents for Organic Chemistry series, aiming at collecting articles on a particular theme that individual researchers in academia or industry can use on a daily basis.
Spurred by the desire to make chemistry a sustainable and "greener" technology, the field of organocatalysis has grown to become one of the most important areas in synthetic organic chemistry. Organic catalysts can often replace potentially toxic metal catalysts and allow reactions to proceed under mild reaction conditions, thereby saving energy costs and rendering chemical processes inherently safer. More importantly perhaps, organocatalysis offers a complementary reactivity in many instances leading to increased versatility.This Handbook describes 126 key reagents for organocatalytic reactions and will be especially useful for professionals in the area of sustainable chemistry, medicinal research, as well as synthetic organic chemists working in academia and the pharmaceutical industry. All the information compiled in this volume is also available in electronic format on Wiley Online Library. The 126 reagents represented here are but a small fraction of the ca. 5,000 reagents available in the electronic Encyclopedia of Reagents for Organic Synthesis (e-EROS). e-EROS offers various search interfaces to locate reagents of interest, including chemical structure, substructure and reactions search modes. e-EROS is updated regularly with new and updated entries.
At last, the long anticipated second edition of the highly successful Encyclopedia of Reagents for Organic Synthesis (EROS) is publishing in print in March 2009. With its wealth of valuable information, excellent editorial leadership and methodical classification, EROS has become the authoritative reference source on reagents and catalysts. This makes EROS vital reading for everybody working in organic synthesis. It has wide appeal, with relevance not only to Organic Chemists, but also to Inorganic, Physical and Analytical Chemists, Materials Scientists, Chemical Engineers, Biochemists, Medicinal and Pharmaceutical Chemists and Pharmacologists. In short, it is an essential product for all academic and industrial chemistry laboratories and libraries. COMPREHENSIVE With its 50,000 reactions and 4,111 reagents, Encyclopedia of Reagents for Organic Synthesis offers readers a substantial wealth of information. Each entry contains, where available: CAS numbers InChI and InChIKeys Alternative names and structures Details on availability and physical properties, including solubility, form in which it’s supplied, purification methods, form obtainable in purification and preparation methods Extensive reviews Examples of transformations for each reagent with reaction schemes Comparison of one agent’s specific properties with those of others capable of equivalent chemistry, together with reaction schemes Stereo-, regio-, and enantio-control properties Required precautions for working with the reagent The various uses and characteristics of each reagent with illustrative examples Related literature METHODICAL Encyclopedia of Reagents for Organic Synthesis has been designed and developed by chemists for chemists. It makes it as easy as possible for users to find the most suitable reagents for performing particular reactions. Reagents are arranged in A to Z format while each reagent entry is presented in a uniform style so that the user is provided with a recognizable format and structure. New in the second edition of Encyclopedia of Reagents for Organic Synthesis: Over 1,000 new reagents Over 620 updated reagents retaining the original text and references whilst adding additional up-to-date information New types of reagents and catalysts In addition to CAS numbers each article now also includes InChI and InChIKeys A standard citation style in the reference list for each reagent An author index
This essential reference contains an authoritative and systematic description of the use of all reagents in organic chemistry. It includes approximately 3500 alphabetically arranged articles, a comparison of reagents with others capable of similar chemistry, a pro and con assessment for each reagent, extensive cross-referencing and substantial subject and molecular formula indexes.
Dieses Fachbuch untersucht systematisch die Leistungsfähigkeit der Silberkatalyse, behandelt neu entwickelte organische Reaktionen und den Reaktionsmechanismus. Der Schwerpunkt liegt auf den Eigenschaften und dem Vergleich der Vorteile diese Katalyse in der organischen Synthese.
The stepping-stone text for students with a preliminary knowledge of organic chemistry looking to move into organic synthesis research and graduate-level coursework Organic synthesis is an advanced but important field of organic chemistry, however resources for advanced undergraduates and graduate students moving from introductory organic chemistry courses to organic synthesis research are scarce. Introduction to Strategies for Organic Synthesis is designed to fill this void, teaching practical skills for making logical retrosynthetic disconnections, while reviewing basic organic transformations, reactions, and reactivities. Divided into seven parts that include sections on Retrosynthesis and Protective Groups; Overview of Organic Transformations; Synthesis of Monofunctional Target Molecules; Synthesis of Target Molecules with Two Functional Groups; Synthesis of Aromatic Target Molecules; Synthesis of Compounds Containing Rings; and Predicting and Controlling Stereochemistry, the book covers everything students need to successfully perform retrosynthetic analyses of target molecule synthesis. Starting with a review of functional group transformations, reagents, and reaction mechanisms, the book demonstrates how to plan a synthesis, explaining functional group analysis and strategic disconnections. Incorporating a review of the organic reactions covered, it also demonstrates each reaction from a synthetic chemist's point of view, to provide students with a clearer understanding of how retrosynthetic disconnections are made. Including detailed solutions to over 300 problems, worked-through examples and end-of-chapter comprehension problems, Introduction to Strategies for Organic Synthesis serves as a stepping stone for students with an introductory knowledge of organic chemistry looking to progress to more advanced synthetic concepts and methodologies.
Purification of Laboratory Chemicals, Eighth Edition, tabulates methods taken from literature for purifying thousands of individual commercially available chemicals. To help in applying this information, the more common processes currently used for purification in chemical laboratories and new methods are discussed. For dealing with substances not separately listed, a chapter is included setting out the usual methods for purifying specific classes of compounds. - Features empirical formulae inserted for every entry - References all important applications of each substance - Updates and confirms the accuracy of all CAS registry numbers, molecular weights, original reference, and physical data - Provides increased coverage of the latest commercial chemical products, including pharmaceutical chemicals, updated safety and hazard material, and expanded coverage of laboratory and work practices and purification methods
Over the last three decades the importance of organosiliconchemistry has greatly increased because it has opened a number ofnew synthetic strategies. Silicon reagents are usually low-cost,versatile and allow a wide range of reactions. This is the firstHandbook to compile essential Silicon containing reagents and makesuse of the leading reagent database e-EROS. Another hotvolume in the series Handbooks of Reagents for OrganicSynthesis, this is a must-have resource for all syntheticchemists working in drug development and medicinal chemistry. For the selection the Editor focussed on three key syntheticapproaches with the greatest impact: 1. Use of silicon as a 'temporary tether' by unifying a reactivepair of functional groups and taking advantage of theirtemplate-biased intramolecular cyclization. 2. The specific use of the silane functionality as a heterot-butyl group, often colloquially referred to as the use ofsilicon as a 'fat proton'. 3. The use of the Brook rearrangement as an 'anion relaystratagem'. A new feature in this Handbook is the reagent finder, analphabetically organized lookup table arranged by organicfunctionality and specific structure of the silicon atom to whichit is bound.
Winner of 2018 PROSE Award for MULTIVOLUME REFERENCE/SCIENCE This encyclopedia offers a comprehensive and easy reference to physical organic chemistry (POC) methodology and techniques. It puts POC, a classical and fundamental discipline of chemistry, into the context of modern and dynamic fields like biochemical processes, materials science, and molecular electronics. Covers basic terms and theories into organic reactions and mechanisms, molecular designs and syntheses, tools and experimental techniques, and applications and future directions Includes coverage of green chemistry and polymerization reactions Reviews different strategies for molecular design and synthesis of functional molecules Discusses computational methods, software packages, and more than 34 kinds of spectroscopies and techniques for studying structures and mechanisms Explores applications in areas from biology to materials science The Encyclopedia of Physical Organic Chemistry has won the 2018 PROSE Award for MULTIVOLUME REFERENCE/SCIENCE. The PROSE Awards recognize the best books, journals and digital content produced by professional and scholarly publishers. Submissions are reviewed by a panel of 18 judges that includes editors, academics, publishers and research librarians who evaluate each work for its contribution to professional and scholarly publishing. You can find out more at: proseawards.com Also available as an online edition for your library, for more details visit Wiley Online Library