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This book presents the latest technological advances in Raman spectroscopy that are presently redrawing the landscape of many fields of biomedical and pharmaceutical R&D. Numerous examples are given to illustrate the application of the new methods.
From the discovery of x-rays in 1895 through the emergence of computed tomography (CT) in the 1970s and magnetic resonance imaging (MRI) in the 1980s, non-invasive imaging has revolutionized the practice of medicine. While these technologies have thoroughly penetrated clinical practice, scientists continue to develop novel approaches that promise to push imaging into entirely new clinical realms, while addressing the issues of dose, sensitivity, or specificity that limit existing imaging approaches. Emerging Imaging Technologies in Medicine surveys a number of emerging technologies that have the promise to find routine clinical use in the near- (less than five years), mid- (five to ten years) and long-term (more than ten years) time frames. Each chapter provides a detailed discussion of the associated physics and technology, and addresses improvements in terms of dose, sensitivity, and specificity, which are limitations of current imaging approaches. In particular, the book focuses on modalities with clinical potential rather than those likely to have an impact mainly in preclinical animal imaging. The last ten years have been a period of fervent creativity and progress in imaging technology, with improvements in computational power, nanofabrication, and laser and detector technology leading to major new developments in phase-contrast imaging, photoacoustic imaging, and optical imaging.
Light Scattering Technology for Food Property, Quality and Safety Assessment discusses the development and application of various light scattering techniques for measuring the structural and rheological properties of food, evaluating composition and quality attributes, and detecting pathogens in food. The first four chapters cover basic concepts, principles, theories, and modeling of light transfer in food and biological materials. Chapters 5 and 6 describe parameter estimation methods and basic techniques for determining optical absorption and scattering properties of food products. Chapter 7 discusses the spatially-resolved measurement technique for determining the optical properties of food and biological materials, whereas Chapter 8 focuses on the time-resolved spectroscopic technique for measuring optical properties and quality or maturity of horticultural products. Chapter 9 examines practical light scattering techniques for nondestructive quality assessment of fruits and vegetables. Chapter 10 presents the theory of light transfer in meat muscle and the measurement of optical properties for determining the postmortem condition and textural properties of muscle foods and meat analogs. Chapter 11 covers the applications of spatially-resolved light scattering techniques for assessing quality and safety of animal products. Chapter 12 looks into light scattering for milk and dairy processing. Chapter 13 examines the applications of dynamic light scattering for measuring the microstructure and rheological properties of food. Chapter 14 shows the applications of a biospeckle technique for assessing the quality and condition of fruits and vegetables. Chapter 15 provides a detailed description of Raman scattering spectroscopic and imaging techniques in food quality and safety assessment. Chapter 16, the final chapter, focuses on applications of light scattering techniques for the detection of food-borne pathogens.
Since the inelastic scattering of light was predicted nearly 100 years ago, Raman spectroscopy has become a mainstay of characterization techniques, with applications in a vast array of fields from chemistry to materials science and nanotechnology, from forensics to geology and art. More recently, it has found usage in the life sciences, and this book hereby outlines the state-of-the-art advances in applications of Raman spectroscopy to human health and biomedicine. It covers a wide range of human health science including medicine (especially cancer), physiology, biological molecules, pharmaceutical science, cells, viruses, microorganisms, and food science. Another highlight is that it describes recent progress on various Raman techniques such as surface-enhanced Raman scattering, tip-enhanced Raman scattering, non-linear Raman spectroscopy, Raman microscopy, and Raman imaging. Novel spectral analysis methods such as chemometrics are also prominently discussed.
Modern Techniques for Food Authentication, Second Edition presents a comprehensive review of the novel techniques available to authenticate food products, including various spectroscopic technologies, methods based on isotopic analysis and chromatography, and other techniques based on DNA, enzymatic analysis and electrophoresis. This new edition pinpoints research and development trends for those working in research, development and operations in the food industry, giving them readily accessible information on modern food authentication techniques to ensure a safe and authentic food supply. It will also serve as an essential reference source to undergraduate and postgraduate students, and for researchers in universities and research institutions. Presents emerging imaging techniques that have proven to be powerful, non-destructive tools for food authentication Includes applications of hyperspectral imaging to reflect the current trend of developments in food imaging technology for each topic area Provides pixel level visualization techniques needed for fast and effective food sample testing Contains two new chapters on Imaging Spectroscopic Techniques
Rapid prototyping is used to design and develop medical devices and instrumentation. This book details research in rapid prototyping of bio-materials for medical applications. It provides a wide variety of examples of medical applications using rapid prototyping, including tissue engineering, dental applications, and bone replacement. Coverage also discusses the emergence of computer aided design in the development of prosthetic devices.
Thanks to the progress made in instruments and techniques, the methods in physical chemistry have developed rapidly over the past few decades, making them increasingly valuable for scientists of many disciplines. These two must-have volumes meet the needs of the scientific community for a thorough overview of all the important methods currently used. As such, this work bridges the gap between standard textbooks and review articles, covering a large number of methods, as well as the motivation behind their use. A uniform approach is adopted throughout both volumes, while the critical comparison of the advantages and disadvantages of each method makes this a valuable reference for physical chemists and other scientists working with these techniques.
This book constitutes the refereed proceedings of the 12th IFIP WG 5.5/SOCOLNET Advanced Doctoral Conference on Computing, Electrical and Industrial Systems, DoCEIS 2021, held in Costa de Caparica, Portugal, in July 2021.* The 34 papers presented were carefully reviewed and selected from 92 submissions. The papers present selected results produced in engineering doctoral programs and focus on technological innovation for industry and service systems. Research results and ongoing work are presented, illustrated and discussed in the following areas: collaborative networks; smart manufacturing; cyber-physical systems and digital twins; intelligent decision making; smart energy management; communications and electronics; classification systems; smart healthcare systems; and medical devices. *The conference was held virtually. Chapters “Characteristics of Adaptable Control of Production Systems and the Role of Self-organization Towards Smart Manufacturing” and “Predictive Manufacturing: Enabling Technologies, Frameworks and Applications” are available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
Biomarker discovery is an important area of biomedical research that may lead to significant breakthroughs in disease analysis and targeted therapy. Biomarkers are biological entities whose alterations are measurable and are characteristic of a particular biological condition. Discovering, managing, and interpreting knowledge of new biomarkers are challenging and attractive problems in the emerging field of biomedical informatics. This volume is a collection of state-of-the-art research into the application of data mining to the discovery and analysis of new biomarkers. Presenting new results, models and algorithms, the included contributions focus on biomarker data integration, information retrieval methods, and statistical machine learning techniques. This volume is intended for students, and researchers in bioinformatics, proteomics, and genomics, as well engineers and applied scientists interested in the interdisciplinary application of data mining techniques.