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"Embryonic Landscapes is Ariel Ruiz i Altaba's remarkable, surprising, intelligent and deeply moving photographic collection produced over the last fifteen years of his career as scientist and photographer. In these images he has captured the essence and external forms of developing embryos and embryonic forms in photographs that recall a recapitulation of art history: From the walls of Lascaux, to arid African landscapes, goyesque images and the paintings of Motherwell, Pollock and Miró.
Devised in the 1940s by the biologist C. H. Waddington, the epigenetic landscape is a metaphor for how gene regulation modulates cellular development. As a scientific model, it fell out of use in the late 1960s but returned at the beginning of the twenty-first century with the advent of big-data genomic research because of its utility among scientists across the life sciences to think more creatively about and to discuss genetics. In Epigenetic Landscapes Susan Merrill Squier follows the model’s cultural trail, from its first visualization by the artist John Piper to its use beyond science. Squier examines three cases in which the metaphor has been imaginatively deployed to illustrate complex systems that link scientific and cultural practices: graphic medicine, landscape architecture, and bioArt. Challenging reductive understandings of epigenetics, Squier boldly reclaims the broader significance of the epigenetic landscape as a figure at the nexus of art, design, and science.
This volume explores the conceptualization and construction of sacred space in a wide variety of faith traditions: Christianity, Hinduism, Islam, Judaism, and the religions of Japan. It deploys the notion of "layered landscapes" in order to trace the accretions of praxis and belief, the tensions between old and new devotional patterns, and the imposition of new religious ideas and behaviors on pre-existing religious landscapes in a series of carefully chosen locales: Cuzco, Edo, Geneva, Granada, Herat, Istanbul, Jerusalem, Kanchipuram, Paris, Philadelphia, Prague, and Rome. Some chapters hone in on the process of imposing novel religious beliefs, while others focus on how vestiges of displaced faiths endured. The intersection of sacred landscapes with political power, the world of ritual, and the expression of broader cultural and social identity are also examined. Crucially, the volume reveals that the creation of sacred space frequently involved more than religious buildings and was a work of historical imagination and textual expression. While a book of contrasts as much as comparisons, the volume demonstrates that vital questions about the location of the sacred and its reification in the landscape were posed by religious believers across the early-modern world.
What determines the direction of evolutionary change? This book provides a revolutionary answer to this question. Many biologists, from Darwin's day to our own, have been satisfied with the answer 'natural selection'. Professor Wallace Arthur is not. He takes the controversial view that biases in the ways that embryos can be altered are just as important as natural selection in determining the directions that evolution has taken, including the one that led to the origin of humans. This argument forms the core of the book. However, in addition, the book summarizes other important issues relating to how embryonic (and post-embryonic) development evolves. Written in an easy, conversational style, this is the first book for students and the general reader that provides an account of the exciting new field of Evolutionary Developmental Biology ('Evo-Devo' to its proponents).
This work adopts a holistic approach to studies on landscape, agriculture, forests and natural sciences. As such, it represents a good starting point for anyone looking to learn more about these topics. The book includes research and studies from 50 contributors who are experts in their respective fields.
At a time when the human genome has been sequenced advances in the life sciences seem to have great potential for human health, industry and the environment throughout Central and Eastern Europe (CEE). Still, for some, potential risks and ethical dilemmas remain, surrounding issues such as the appropriate use of GM crops, stem cells, genetic information, the nature of intellectual property and other challenges that come with EU accession. This book is the first of its kind to bring together experts from across Europe to explore the landscape of current life science policy and industrial development in CEE, including implications for economies, regulatory and legal frameworks, health care, ethics and human rights. It will be essential reading for researchers and students in science and technology studies, development, sociology, politics and law, and those interested in life science development in transition economies.
The need for the development of biomaterials as scaffold for tissue regeneration is driven by the increasing demands for materials that mimic functions of extracellular matrices of body tissues. Unfolding the Biopolymer Landscape provides a unique account of “biopolymeric interventions” inherent to biotechnological applications, soft tissue engineering, ophthalmic drug delivery, biotextiles, environmentally responsive systems, neurotherapeutics, and emulsions-based formulations for food and pharmaceutical applications. Chapters in this volume also cover biomedical applications and implications of cationic polymers, collagen-based substrates, multifunctional polymers, shape memory biopolymers, hybrid semisynthetic biomaterials, microbial exopolysaccharides, biomaterials mimicking the extracellular microenvironment, derivatized polysaccharides, and metallic biomaterials. Each chapter is distinctly written by experts in the respective fields and emphasis is given on the mechanistic profile of the performance of biopolymers and biomedical applications. This book provides both basic and advanced biopolymer information for scientific experts and early career researchers in the field of drug delivery, tissue engineering, nanomedicine, food technology, peptide science, biomaterial design, and nutrition. This volume provides a unique account of “biopolymeric interventions” inherent to biotechnological applications, soft tissue engineering, ophthalmic drug delivery, biotextiles, environmentally responsive systems, neurotherapeutics, and emulsions-based formulations for food and pharmaceutical applications.
This report provides an overview of the global patent landscape in the area of palm oil production and waste exploitation, and includes national patent applications from Malaysia. It covers patenting activity related to technologies in production of palm oil and palm kernel oil, and treatment of waste from palm oil production.
Immune landscape of pancreatic cancer development and drug resistance explores the advances in immune-based therapies aimed at harnessing the power of the immune system against pancreatic cancer and rewiring tumor microenvironments to eradicate pancreatic cells. With a strong focus on the development of therapeutic methods to improve the survival rates of pancreatic cancer, this book also shows the latest trends in immune targeted approaches for pancreatic cancer treatment. In 12 chapters Immune landscape of pancreatic cancer development and drug resistance discusses the current understanding of PC development and its various mutational and immune features and explore some of the new immune-based therapies aimed at targeting pancreatic cancer. It covers the urgent need for developing novel therapeutic modalities and aims at delineating future fields and avenues of research in pancreatic cancer treatment. The book provides the reader with an updated understanding of the immune landscape of PC and an all-encompassing overview of the latest trends in immune targeted approaches for PC treatment. This book is a valuable resource for health professionals, scientists and researchers, students, and all those who wish to broaden their knowledge of the advances in immunotherapy in pancreatic cancer. - Summarizes the potential combination strategies and latest clinical trials in pancreatic cancer - Provides an in-depth overview of our current understanding of pancreatic cancer development, including its mutational and immune features - Explores some of the new immune-based therapies aimed at targeting PC - Shows pancreatic cancer progression and basic elements in tumor microenvironments and their role in PC progression, also covering immunotherapy strategies
Topic Editor Dr. Patrick Tang holds patents related to anticancer therapy and diabetic prevention. All other Topic Editors declare no competing interests with regards to the Research Topic.