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Taking a new product from the design stage to large-scale production in a profitable, efficient manner can challenge the processes of even the most advanced companies. Lapses in these processes drive up the cost of new products, and hinder their launch into the marketplace. Effective Transition from Design to Production provides an expeditio
Developing Solid Oral Dosage Forms: Pharmaceutical Theory and Practice, Second Edition illustrates how to develop high-quality, safe, and effective pharmaceutical products by discussing the latest techniques, tools, and scientific advances in preformulation investigation, formulation, process design, characterization, scale-up, and production operations. This book covers the essential principles of physical pharmacy, biopharmaceutics, and industrial pharmacy, and their application to the research and development process of oral dosage forms. Chapters have been added, combined, deleted, and completely revised as necessary to produce a comprehensive, well-organized, valuable reference for industry professionals and academics engaged in all aspects of the development process. New and important topics include spray drying, amorphous solid dispersion using hot-melt extrusion, modeling and simulation, bioequivalence of complex modified-released dosage forms, biowaivers, and much more. - Written and edited by an international team of leading experts with experience and knowledge across industry, academia, and regulatory settings - Includes new chapters covering the pharmaceutical applications of surface phenomenon, predictive biopharmaceutics and pharmacokinetics, the development of formulations for drug discovery support, and much more - Presents new case studies throughout, and a section completely devoted to regulatory aspects, including global product regulation and international perspectives
This volume of selected articles is being released in light of the new economic, social and environmental challenges Europe and the United States have been faced with following the end of the Cold War and in the evolving era of globalization. National security, immigration and the provision of health and other key social services call for a radically different outlook in terms of policy discussions. The contributors of this book focus on seven key policy issues and challenges that currently affect the United States and Europe: income distribution, the gender pay gap, crime and security, unemployment, health care, the demographic question and environmental regulation. The purpose of this volume is to analyze how public policy within the European context is responding to the challenges posed by this new global era.
This book promotes student-centered approaches to the learning process, allowing students to develop skills and competences that traditional, passive learning methods cannot foster. In turn, supporting active learning with digital technology tools creates new possibilities in terms of pedagogical design and implementation. This book addresses the latest research and practice in the use of technology to promote active learning. As such, on the one hand, it focuses on active pedagogical methodologies like problem-based learning, design thinking and agile approaches; on the other, it presents best practice cases on the use of digital environments to support these methodologies. Readers will come to understand and learn to apply active learning methodologies, either by replicating the best practices presented here, or by creating their own methods.
This textbook explores major issues and concepts in organizational structure and design. It details strategic and business issues that merit consideration while framing or designing the organizational structure. Working with a range of industry examples and case studies, this volume: Relates organizational structure and design issues with organizational culture and change management, power and politics, and policies and strategies Covers several key topics, including the structure-strategy debate, viable system model, issues pertaining to organizational culture, change management, power, and conflict Discusses various models of organizational structure like matrix, global business unit, strategic business unit, hybrid, functional and divisional, modular, networked, agile, helix, etc., in relation to organizational practices and their strategic influence over the organization Enables readers to challenge organizational design in times of uncertainty Concise, lucid, and engaging, this book will be useful to students, academics, management researchers, and industry professionals in the fields of general management, organizational behaviour, and human resource management and development.