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This thesis describes an evaluation of the impact of administering recombinant bovine somatotropin (rbST) before calving on health, milk production, reproductive performance and dry matter intake (DMI) of lactating dairy cows. In addition, this thesis includes an evaluation of the cost of subclinical ketosis (SCK), economic value of using Rumensin® Controlled Release Capsules (CRC) for disease prevention and the economic value of using propylene glycol (PG) for treatment of SCK after being diagnosed with different cow-side tests. One randomized clinical trial was conducted on 4 commercial dairy herds in Southern Ontario and at the University of Guelph where rbST was administered every other week starting at 28-22 days before calving until cows calved. The key finding of this study was that pre-partum rbST administration had no significant clinical impact on health and performance of dairy cows after calving. A spreadsheet was constructed to perform the economic analysis of ketosis cost and treatment. It was estimated that one case of SCK can cost up to $350. The economic value of using CRC to reduce ketosis depends on the prevalence of ketosis-related diseases in a herd. Using a cow-side test with high sensitivity and specificity to diagnose SCK pays off through minimizing the losses by classifying fewer cows as false negatives and therefore treating more sick cows and mitigating the negative impact of SCK. Results presented in this thesis highlight the insufficiency of rbST administration in the pre-partum period only, to improve health in the transition period and to improve cow performance after calving. Results of an economic analysis highlight the high cost impact of SCK and the importance of reducing its incidence through implementing management during the transition period.
In the past decade, animal scientists have learned that administering recombinantly derived somatotropin (growth hormone) to cows improves milk production and that giving beta-adrenergic agonists to meat animals improves productivity and leanness. In order for these metabolic modifiers to yield benefits, however, sound management of the animals' nutrition is necessary. This volume reports on how these substances work in the animals' metabolism, what effects they might have on nutrient requirements of domestic livestock, and what information should be developed further by investigators. The book explores the current understanding of the biology, structure, mechanisms of action, and treatment effects of somatotropin, beta-adrenergic agonists, and anabolic steroids. A companion volume to the Nutrient Requirements of Domestic Animals series, this authoritative volume will be required reading for animal scientists, researchers, veterinarians, livestock farmers, and faculty and students in university animal veterinary science programs.
A guide to the field of animal health economics and its underlying methodology. Supplied with this book is a diskette, containing practical exercises (in computer spreedsheets) on the various methods and techniques in animal health economics, including production function analysis.