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"Dost thou love life? Then do not squander time, for that's the stuff life is made oj': Benjamin Franklin This book describes the technical principles and applications of echo-planar imaging (EPI) which, as much as any other technique, has shaped the develop ment of modern magnetic resonance imaging (MRI). The principle of EPI, namely, the acquisition of multiple nuclear magnetic resonance echoes from a single spin excitation, has made it possible to shorten the previously time-con suming MRI data acquisition from minutes to much less than a second. Interest ingly, EPI is one of the oldest MRI techniques, conceived in 1976 by Sir Peter Mansfield only 4 years after the initial description of the principles of MRI. One of the inventors of MRI himself, Mansfield realized that fast data acquisition would be paramount in bringing medical applications of MRI to full fruition. The technological challenges in implementing EPI, however, were formidable. Until the end of the 1980s few people believed that EPI would be clinically useful, since its complexity was far greater than that of "conventional" MRI methods.
MR is a powerful modality. At its most advanced, it can be used not just to image anatomy and pathology, but to investigate organ function, to probe in vivo chemistry, and even to visualise the brain thinking. However, clinicians, technologists and scientists struggle with the study of the subject. The result is sometimes an obscurity of understanding, or a dilution of scientific truth, resulting in misconceptions. This is why MRI from Picture to Proton has achieved its reputation for practical clarity. MR is introduced as a tool, with coverage starting from the images, equipment and scanning protocols and traced back towards the underlying physics theory. With new content on quantitative MRI, MR safety, multi-band excitation, Dixon imaging, MR elastography and advanced pulse sequences, and with additional supportive materials available on the book's website, this new edition is completely revised and updated to reflect the best use of modern MR technology.
New edition explores contemporary MRI principles and practices Thoroughly revised, updated and expanded, the second edition of Magnetic Resonance Imaging: Physical Principles and Sequence Design remains the preeminent text in its field. Using consistent nomenclature and mathematical notations throughout all the chapters, this new edition carefully explains the physical principles of magnetic resonance imaging design and implementation. In addition, detailed figures and MR images enable readers to better grasp core concepts, methods, and applications. Magnetic Resonance Imaging, Second Edition begins with an introduction to fundamental principles, with coverage of magnetization, relaxation, quantum mechanics, signal detection and acquisition, Fourier imaging, image reconstruction, contrast, signal, and noise. The second part of the text explores MRI methods and applications, including fast imaging, water-fat separation, steady state gradient echo imaging, echo planar imaging, diffusion-weighted imaging, and induced magnetism. Lastly, the text discusses important hardware issues and parallel imaging. Readers familiar with the first edition will find much new material, including: New chapter dedicated to parallel imaging New sections examining off-resonance excitation principles, contrast optimization in fast steady-state incoherent imaging, and efficient lower-dimension analogues for discrete Fourier transforms in echo planar imaging applications Enhanced sections pertaining to Fourier transforms, filter effects on image resolution, and Bloch equation solutions when both rf pulse and slice select gradient fields are present Valuable improvements throughout with respect to equations, formulas, and text New and updated problems to test further the readers' grasp of core concepts Three appendices at the end of the text offer review material for basic electromagnetism and statistics as well as a list of acquisition parameters for the images in the book. Acclaimed by both students and instructors, the second edition of Magnetic Resonance Imaging offers the most comprehensive and approachable introduction to the physics and the applications of magnetic resonance imaging.
Comprehensive medical imaging physics notes aimed at those sitting the first FRCR physics exam in the UK and covering the scope of the Royal College of Radiologists syllabus. Written by Radiologists, the notes are concise and clearly organised with 100's of beautiful diagrams to aid understanding. The notes cover all of radiology physics, including basic science, x-ray imaging, CT, ultrasound, MRI, molecular imaging, and radiation dosimetry, protection and legislation. Although aimed at UK radiology trainees, it is also suitable for international residents taking similar examinations, postgraduate medical physics students and radiographers. The notes provide an excellent overview for anyone interested in the physics of radiology or just refreshing their knowledge. This third edition includes updates to reflect new legislation and many new illustrations, added sections, and removal of content no longer relevent to the FRCR physics exam. This edition has gone through strict critique and evaluation by physicists and other specialists to provide an accurate, understandable and up-to-date resource. The book summarises and pulls together content from the FRCR Physics Notes at Radiology Cafe and delivers it as a paperback or eBook for you to keep and read anytime. There are 7 main chapters, which are further subdivided into 60 sub-chapters so topics are easy to find. There is a comprehensive appendix and index at the back of the book.
Magnetic Resonance Imaging (MRI) is among the most important medical imaging techniques available today. There is an installed base of approximately 15,000 MRI scanners worldwide. Each of these scanners is capable of running many different "pulse sequences", which are governed by physics and engineering principles, and implemented by software programs that control the MRI hardware. To utilize an MRI scanner to the fullest extent, a conceptual understanding of its pulse sequences is crucial. Handbook of MRI Pulse Sequences offers a complete guide that can help the scientists, engineers, clinicians, and technologists in the field of MRI understand and better employ their scanner. - Explains pulse sequences, their components, and the associated image reconstruction methods commonly used in MRI - Provides self-contained sections for individual techniques - Can be used as a quick reference guide or as a resource for deeper study - Includes both non-mathematical and mathematical descriptions - Contains numerous figures, tables, references, and worked example problems
Functional Magnetic Resonance Imaging (fMRI) has become a standard tool for mapping the working brain's activation patterns, both in health and in disease. It is an interdisciplinary field and crosses the borders of neuroscience, psychology, psychiatry, radiology, mathematics, physics and engineering. Developments in techniques, procedures and our understanding of this field are expanding rapidly. In this second edition of Introduction to Functional Magnetic Resonance Imaging, Richard Buxton – a leading authority on fMRI – provides an invaluable guide to how fMRI works, from introducing the basic ideas and principles to the underlying physics and physiology. He covers the relationship between fMRI and other imaging techniques and includes a guide to the statistical analysis of fMRI data. This book will be useful both to the experienced radiographer, and the clinician or researcher with no previous knowledge of the technology.
Professor Derek Jones, a world authority on diffusion MRI, has assembled most of the world's leading scientists and clinicians developing and applying diffusion MRI to produce an authorship list that reads like a "Who's Who" of the field and an essential resource for those working with diffusion MRI. Destined to be a modern classic, this definitive and richly illustrated work covers all aspects of diffusion MRI from basic theory to clinical application. Oxford Clinical Neuroscience is a comprehensive, cross-searchable collection of resources offering quick and easy access to eleven of Oxford University Press's prestigious neuroscience texts. Joining Oxford Medicine Online these resources offer students, specialists and clinical researchers the best quality content in an easy-to-access format.
Every day MRI is gaining more and more appreciation by all me die al specialists for its impressive quality of anatomical images. This morphological information gives consistent help in terms of earlier diagnosis, lesion characterisation, and definition of the extent of disease. However, morphology is not the only infor mation obtained through MRI. Recently, a large number of researchers have exploited the possibility of also obtaining functional information with MRI. Results of brain activation studies have been initially performed in Boston and have been confirmed by investiga tors all over the world. Important functional data can be obtained not only on the brain, but also on the heart and on parenchymal organs. The diffusion nowadays of commercial MR units used with high field gradient and echo planar techniques allows functional data to be obtained in any routine clinical activity. This book appears at the right time to provide information on fMRI to all MR users wanting to obtain clinical experience with this new too1. We thank the authors of each paper for their efforts and for the outstanding contribution both to the seminar and on these pages. We are especially grateful to BRACCO INTERNATIONAL, who generous ly supported the publication of this Syllabus and the European Seminar on Di agnostic and Interventional Radiology (ESDIR), held in Rome on October 26- 28,1995. We hope that this editorial work will be valid as a reference collection of pa pers on this new field of medicine.
The 11th International Conference on Medical Imaging and Computer Assisted Intervention, MICCAI 2008, was held at the Helen and Martin Kimmel Center of New York University, New York City, USA on September 6–10, 2008. MICCAI is the premier international conference in this domain, with - depth papers on the multidisciplinary ?elds of biomedical image computing and analysis, computer assisted intervention and medical robotics. The conference brings together biological scientists, clinicians, computer scientists, engineers, mathematicians, physicists and other interested researchers and o?ers them a forum to exchange ideas in these exciting and rapidly growing ?elds. The conference is both very selective and very attractive: this year we - ceived a record number of 700 submissions from 34 countries and 6 continents, fromwhich258papers were selectedfor publication,whichcorrespondsto a s- cess rate of approximately 36%. Some interesting facts about the distribution of submitted and accepted papers are shown graphically at the end of this preface. The paper selection process this year was based on the following procedure, which included the introduction of several novelties over previous years. 1. A ProgramCommittee (PC) of 49 members was recruited by the Program Chairs,to getthenecessarybody ofexpertiseandgeographicalcoverage.All PC members agreed in advance to participate in the ?nal paper selection process. 2. Key words grouped in 7 categories were used to describe the content of the submissions and the expertise of the reviewers.
Magnetic Resonance Imaging is a very important clinical imaging tool. It combines different fields of physics and engineering in a uniquely complex way. MRI is also surprisingly versatile, 'pulse sequences' can be designed to yield many different types of contrast. This versatility is unique to MRI. This short book gives both an in depth account of the methods used for the operation and construction of modern MRI systems and also the principles of sequence design and many examples of applications. An important additional feature of this book is the detailed discussion of the mathematical principles used in building optimal MRI systems and for sequence design. The mathematical discussion is very suitable for undergraduates attending medical physics courses. It is also more complete than usually found in alternative books for physical scientists or more clinically orientated works.