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Humanity’s ever-increasing hunger for mineral raw materials, caused by a growing global population and ever increasing standards of living, has resulted in economic geology becoming a subject of urgent importance. This book provides a broad panorama of mineral deposits, covering their origin and geological characteristics, the principles of the search for ores and minerals, and the investigation of newly found deposits. Practical and environmental issues that arise during the life cycle of a mine and after its closure are addressed, with an emphasis on sustainable and "green" mining. The central scientific theme of the book is to place the extraordinary variability of mineral deposits in the frame of fundamental geological processes. The book is written for earth science students and practicing geologists worldwide. Professionals in administration, resource development, mining, mine reclamation, metallurgy, and mineral economics will also find the text valuable. Economic Geology is a fully revised translation of the the fifth edition of the German language text Mineralische und Energie-Rohstoffe. Additional resources for this book can be found at: www.wiley.com/go/pohl/geology. The author's website can be found at: http://www.walter-pohl.com.
Oral Cytology: A Concise Guide provides a state-of-the-art review of the major issues specific to the field of oral cytology. The sections of the book have been structured to review the complexities of sample collection, manual/automated analysis, pitfalls, gray zones and controversies in diagnosis, as well as, issues not covered by other available materials. Recent advancements in ancillary techniques like DNA ploidy, image analysis and molecular biology are discussed in detail. This useful text is extensively illustrated with patient and microscopic pictures, which will further highlight the clinical application. Throughout the text, simultaneous inclusion of both cytologic and histologic images will allow cyto-histological correlation. Readers will find descriptions of techniques offering greater simplicity, speed, patient comfort and cost effectiveness, as well as improved diagnostic precision. This bench-side reference is a unique and valuable resource in the field of oral cytology, both for those currently in training and clinicians dealing with the diagnosis of oral lesions.
This book presents recent developments in the field of environmental biotechnology. Three major forces are currently driving this discipline: the exploration of microbial diversity by genetic and genomic tools, the ongoing progress in the modelling of various transient phenomena, and environmental biotechnology. This book provides a state-of-art-overview of developments in the field of environmental biotechnology concerning exploration, implementation, modelling, economic development and safety. It comprises selected, peer-reviewed papers that were presented at the European Symposium on Environmental Biotechnology (ESEB) 2004, held in Oostende, Belgium, April 2004.
At the dawn of the 21st century, biotechnology is emerging as a key enabling technology for sustainable environmental protection and stewardship. Biotechnology for the Environment: Strategy and Fundamentals captures the dynamism of environmental biotechnology as it addresses the molecular functioning of microorganisms as cleanup agents, their communal interactions in natural and polluted ecosystems, and the foundations of practical bioremediation processes. Chapters on biological pollution control in the chemical industry, biodegradation of persistent molecules (halogenated compounds, polycyclic aromatic hydrocarbons, polychlorinated biphenyls, pesticides, detergents, etc.), microbial diversity with impact on global change, bioaugmentation strategies, and sensors for ecotoxicological monitoring, will be of value to environmental scientists, engineers, and decision-makers involved in the development, evaluation, or implementation of biological treatment systems. For information on Soil Remediation, see Focus on Biotechnology volume 3B, and for information on Waste Water and Waste Gas Handling, see Focus on Biotechnology volume 3C.
The application of enzymes or whole cells (fermentatively active or resting; microbial, plant, or animal) to carry out selective transformations of commercial importance is the central theme of industrial biocatalysis. Traditionally, biocatalysis has been in the domain of the life scientist or biochemical engineer. However, recent advances in this field have enabled biocatalytic processes to compete head on with, and in some cases out perform, conventional chemical processing. Chemo-biocatalytic systems are being developed thereby combining the most attractive features of bio catalysts, namely high specificity, with those of chemical catalysts, such as high reactivities and wide substrate specificities. Hence, synthetic chemists and chemical engineers are now beginning to use biocatalysts as highly selective reagents in chemical synthesis and processing. This book is about biocatalysts and their past, present, and potential applications in the food, pharmaceutical, and chemical industries. The con cept of the book did not emanate from a meeting. Rather, it is a compila tion of selected examples where biocatalysis either has already made a significant impact in the aforementioned industries, or has the potential to make a substantial contribution. I have been fortunate to have assembled contributions from world-class researchers in the field of biocatalysis. Their timely contributions are sincerely appreciated.
The European project MINOTAURUS explored innovative bio-processes to eliminate emerging and classic organic pollutants. These bio-processes are all based on the concept of immobilization of biocatalysts (microorganisms and enzymes) and encompass bioaugmentation, enzyme technology, rhizoremediation with halophytes, and a bioelectrochemical remediation process. The immobilization-based technologies are applied as engineered ex situ treatment systems as well as natural systems in situ for the bioremediation of groundwater, wastewater and soil. The selection and application of tailored physico-chemical, molecularbiological and ecotoxicological monitoring tools combined with a rational understanding of engineering, enzymology and microbial physiology is a pertinent approach to open the black-box of the selected technologies. Reliable process monitoring constitutes the basis for developing and refining biodegradation kinetics models, which in turn improve the predictability of performances to be achieved with technologies. Immobilised Biocatalysts for Bioremediation of Groundwater and Wastewater delivers insight into the concepts and performance of a series of remediation approaches. A key strength of this book is to deliver results from lab-scale through to piloting at different European reference sites. It further suggests frameworks for structuring and making evidence-based decisions for the most appropriate bioremediation measures.
Consolidating and expanding current, fundamental notions of virology and animal cell cultivation, this practical reference examines the development of insect cell culture techniques for the production of recombinant proteins and insect pathogenic viruses.;Resolving on-the-job problems such as sparging cell damage and reduced infectivity cells, Insect Cell Culture Engineering: includes special introductory material as well as background information on insect pathogenic viruses, the molecular biology of baculoviruses and bioreactor design; offers advice on how to save time when deciding which insect cell line, bioreactor and medium to exploit; discusses the preparation of mathematical modelling in animal cell culture; addresses the concerns associated with insect cell immobilization and the use of serum-free culture media; provides insights into the protective effects of polymer additives and insect cell gene expression in pharmaceutical research; and analyzes process scale-up and reactor design.;Bridging the gap between laboratory research and pilot plant scale insect culture/baculovirus technology, Insect Cell Culture Engineering is designed as a reference for biochemical and bioprocess engineers, bioprocess technologists, biochemists, molecular and cell biologists, microbiologists, and upper-level undergraduate and graduate students in these disciplines.
Vitamins are a group of physiologically very important, chemically quite complex organic compounds, that are essential for humans and animals. Some vitamins and other growth factors behave as antioxidants, while some can be considered as biopigments. As their chemical synthesis is laborious, their biotechnology-based synthesis and production via microbial fermentation has gained substantial interest within the last decades. Recent progress in microbial genetics and in metabolic engineering and implementation of innovative bioprocess technology has led to a biotechnology-based industrial production of many vitamins and related compounds. Divided into three sections, this volume covers: 1. water-soluble vitamins 2. fat-soluble vitamin compounds and 3. other growth factors, biopigments, and antioxidants. They are all reviewed systematically: from natural occurrence and assays, via biosynthesis, strain development, to industrially-employed biotechnological syntheses and applications.