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Forensic chemists and toxicologists work with drugs and poisons, but they each start with different evidence. Forensic chemists working in a crime lab must determine if the physical evidence they receive is an illegal substance such as marijuana or cocaine. They are also responsible for samples—including fire debris, soil, paint, glass, explosives, and fibers—obtained from suspected arson crimes. Toxicologists, on the other hand, work with biological evidence such as blood, saliva, urine, and feces, using analytical chemistry to identify chemical traces and unmetabolized drugs. They often work in labs associated with a medical examiner’s office or a hospital. Drugs, Poisons, and Chemistry, Revised Edition touches on all aspects of forensic chemistry, including how it developed and what it includes today. This useful eBook covers a short history of forensic chemistry, detailing the story of arsenic and those who developed effective tests to detect it. Delving into the tools and techniques used by forensic chemists—ranging from such familiar tools as the microscope to slightly more obscure tools as the use of antibodies to detect toxins—this comprehensive resource provides a thorough examination of these three main areas of forensic chemistry. Chapters include: History and Pioneers Scientific Principles, Instrumentation, and Equipment Toxicology: Drugs and Poisons in the Body Forensic Drug Analysis Conclusions: The Future of Drugs, Poisons, and Chemistry.
This manual and reference work provides a source of analytical data for drugs and related substances. It is intended for scientists faced with the difficult problem of identifying a drug in a pharmaceutical product, in a sample of tissue or body fluid, from a living patient or in post-mortem material. Volume One contains 32 chapters covering the practice of and analytical procedures used in forensic toxicology. Volume Two contains over 1750 drug and related substance monographs detailing: physical properties; analytical methods; pharmacokinetic data; and toxicity data, as well as expanded indexes and appendices. These volumes should be useful for all forensic and crime laboratories, toxicologists and analytical chemists, pathologists, poison information centres and clinical pharmacology departments.
Equal parts true crime, twentieth-century history, and science thriller, The Poisoner's Handbook is "a vicious, page-turning story that reads more like Raymond Chandler than Madame Curie." —The New York Observer “The Poisoner’s Handbook breathes deadly life into the Roaring Twenties.” —Financial Times “Reads like science fiction, complete with suspense, mystery and foolhardy guys in lab coats tipping test tubes of mysterious chemicals into their own mouths.” —NPR: What We're Reading A fascinating Jazz Age tale of chemistry and detection, poison and murder, The Poisoner's Handbook is a page-turning account of a forgotten era. In early twentieth-century New York, poisons offered an easy path to the perfect crime. Science had no place in the Tammany Hall-controlled coroner's office, and corruption ran rampant. However, with the appointment of chief medical examiner Charles Norris in 1918, the poison game changed forever. Together with toxicologist Alexander Gettler, the duo set the justice system on fire with their trailblazing scientific detective work, triumphing over seemingly unbeatable odds to become the pioneers of forensic chemistry and the gatekeepers of justice. In 2014, PBS's AMERICAN EXPERIENCE released a film based on The Poisoner's Handbook.
Forensic Chemistry, Third Edition, the new edition of this ground-breaking book, continues to serve as the leading forensic chemistry text on the market. Fully updated, this edition describes the latest advances in current forensic chemistry analysis and practice. New and expanded coverage includes rapid advances in forensic mass spectrometry, NMR, and novel psychoactive substances (NPSs). Topics related to seized drug analysis, toxicology, combustion and fire investigation, explosives, and firearms discharge residue are described and illustrated with case studies. The role of statistics, quality assurance/quality control, uncertainty, and metrology are integrated into all topics. More pharmacological and toxicokinetic calculations are presented and discussed. Hundreds of color figures, nearly 450 total, along with graphs, illustrations, worked example problems, and case descriptions are used to show how analytical chemistry is applied to forensic practice. Coverage offer students insight into the legal context in which forensic chemistry is conducted and introduces them to the sample types and sample matrices frequently encountered in forensic laboratories.
Provides the means to identify and quantify drugs and other toxic substances in situations of overdose or poisoning and to interpret analytical results. Includes an analysis of toxic metals and pesticides.
An introduction to pharmaceutical chemistry for undergraduate pharmacy, chemistry and medicinal chemistry students. Essentials of Pharmaceutical Chemistry is a chemistry introduction that covers all of the core material necessary to provide an understanding of the basic chemistry of drug molecules. Now a core text on many university courses, it contains numerous worked examples and problems
About half of all the medicines prescribed by doctors are not taken by their patients. One of the reasons most commonly given by patients for not taking drugs is that they feel unhappy about taking medicines which they do not understand and of which they are afraid. This book attempts to rectify this problem by showing in clear, non-technical language how medicines and other drugs work in the body to reduce the effects of disease. Most chapters include fascinating background information on how some of our most important drugs were discovered, along with intriguing and often amusing anecdotes about the drugs and the people behind their discovery. Each chapter also includes a summary of the key points together with illustrations, photographs or diagrams to summarise the main groups and how they work in the body. The book covers all the major groups of drugs, with complete listings of all the drugs available in the UK and the USA, so that the reader can locate his or her specific drug and read about the actions of the drugs in that group. The various chapters cover drugs used to treat high blood pressure, heart disease, diabetes, nausea, vomiting, diarrhoea, constipation, ulcers, cancers, infections, impotence, incontinence, arthritis, osteoporosis, as well as hormone replacement therapy, oral contraceptives and drugs used in disorders of the brain such as schizophrenia, depression, Parkinson's disease, Alzheimer's disease and epilepsy. There is also a chapter on drugs which are abused such as cannabis, alcohol, nicotine and ecstasy, and a chapter covering some of the poisons we encounter, such as carbon monoxide, arsenic, sheep dip, and the venoms of snakes, spiders, scorpions and marine organisms. Here, then, a fascinating survey of how chemicals have their effects in the body. It shows how drugs work and explains why it is that taking some medicines for many years is far safer than suffering the long-term effects of disease. Pills, Potions and Poisons is an entertaining read that should also help to improve your health and quality of life.
The instant-answer guide clinicians turn to first for on-the-spot treatment of poisoning and drug overdose emergencies A Doody’s Core Title for 2021! “...a great addition to any emergency department library when rapid reference is needed to treat and diagnose the poisoned patient.” -- Annals of Emergency Medicine (Reviewing previous edition) Designed to be used during toxicologic emergencies where every moment counts, Poisoning & Drug Overdose, Seventh Edition delivers critical information on the effective diagnosis and treatment of drug-related emergencies and chemical exposures. This at-a-glance guide is enhanced by detailed tables and charts, extensive cross referencing, and a comprehensive index featuring generic, chemical, and brand names. Poisoning & Drug Overdose is divided into four sections: Section 1 leads readers through initial emergency management, including treatment of coma, hypotension, and other common complications; physical and laboratory diagnosis; and methods of decontamination and enhanced elimination of poisons Section II provides detailed information on 150 common drugs and poisons Section III describes the use and side effects of 60 antidotes and therapeutic drugs Section IV describes the medical management of chemical spills and occupations chemical exposures and includes a table of more than 500 industrial chemicals • Thoroughly updated to reflect newly released drugs, new information on existing drugs, and coverage of the latest black box (and other) warnings • NEW to this edition: information on drug-environmental exposure interactions, coverage of environmental toxins such as mold, asbestos, and others
This updated and revised edition delineates the basic concepts and fundamental principles needed to grasp current issues in modern toxicology. In addition, new contributions help to redefine the book's scope and coverage, and illuminate new and emerging areas of toxicologic interest.