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Drug-Acceptor Interactions: Modeling theoretical tools to test and evaluate experimental equilibrium effects suggests novel theoretical tools to test and evaluate drug interactions seen with combinatorial drug therapy. The book provides an in-depth, yet controversial, exploration of existing tools for analysis of dose-response studies at equilibrium or steady state. The book is recommended reading for post-graduate students and researchers engaged in the study of systems biology, networks, and the pharmacodynamics of natural or industrial drugs, as well as for medical clinicians interested in drug application and combinatorial drug therapy. Even people without mathematical skills will be able to follow the pros and cons of reaction schemes and their related distribution equations. Chapter 9 is a hands-on guide for software to plot, fit and analyze one’s own data.
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This is a source book of adverse drug reactions covering their clinical importance, mechanisms and management. This fourth edition has been revised from an extensive database. Major interaction mechanisms are followed by alphabetically-arranged material covering all the drug groups. As with prior editions, there is a series of monographs with a consistent plan devised to offer quick and easy reading. Both British and American drug names have been used throughout the book and bibliogrpahies are provided for those who wish to use the book as a reference source.
Prescribing more than one drug to a patient raises the possibility of one drug affecting the intesity of action, duration of action, and the occurrence of serious side effects assoicated with another drug. 'The Handbook of Drug Interactions' provides an easy to use, clinically relevant approach to this increasingly complex problem, bringing together information from all available sources. For each drug a simple, at-a-glance table gives an immediate guide to whether action is increased, decreased, or changed in other ways by co-administered drugs. These tables are then cross-referred to more detailed text that indicates what action needs to be taken. Mechanisms of interactions and the latest references are included for those with a particular interest in the subject. Drugs are grouped according to their clinical use and there is minimal use of complicated pharmacological terminology. The index includes alternative drug names to ensure relevance around the world.
Handbook of Drug-Nutrient Interactions, Second Edition is an essential new work that provides a scientific look behind many drug-nutrient interactions, examines their relevance, offers recommendations, and suggests research questions to be explored. In the five years since publication of the first edition of the Handbook of Drug-Nutrient Interactions new perspectives have emerged and new data have been generated on the subject matter. Providing both the scientific basis and clinical relevance with appropriate recommendations for many interactions, the topic of drug-nutrient interactions is significant for clinicians and researchers alike. For clinicians in particular, the book offers a guide for understanding, identifying or predicting, and ultimately preventing or managing drug-nutrient interactions to optimize patient care. Divided into six sections all chapters have been revised or are new to this edition. Chapters balance the most technical information with practical discussions and include outlines that reflect the content; discussion questions that can guide the reader to the critical areas covered in each chapter, complete definitions of terms with the abbreviation fully defined and consistent use of terms between chapters. The editors have performed an outstanding service to clinical pharmacology and pharmaco-nutrition by bringing together a multi-disciplinary group of authors. Handbook of Drug-Nutrient Interactions, Second Edition is a comprehensive up-to-date text for the total management of patients on drug and/or nutrition therapy but also an insight into the recent developments in drug-nutrition interactions which will act as a reliable reference for clinicians and students for many years to come.
With contributions from the fields of pharmacy, dietetics, and medicine, Handbook of Food-Drug Interactions serves as an interdisciplinary guide to the prevention and correction of negative food-drug interactions. Rather than simply list potential food-drug interactions, this book provides explanations and gives specific recommendations based on th
For twenty years this book, now in its 5th edition, has provided information on adverse drug interactions that is unrivalled in coverage and scholarship. Adverse drug reactions, many of them ascribable to interactions with other drugs or with chemical substances in food or the environment, are thought to cause or complicate one in twenty of hospital admissions. The book is conveniently divided into two parts: Part 1 comments on drug interactions and their mechanisms, on a pharmacokinetic and pharmacodynamic level, while Part 2 consists of drug interaction tables, divided and subdivided into categories of disorders, and the drugs used in the treatment of these disorders. If safety in drugs is to improve, education of prescribers is vitally important. This book, with its up-to-date and coordinated approach, serves that purpose well. The real threat, as the authors remind us, is the ignorance of practitioners, not the drug itself. The volume is therefore an essential addition to the shelves of those responsible for the prescription of drugs, in order to prevent a potential backlash when used in combination with other drugs or chemical substances.
Did You Know? Eating too much broccoli could be deadly if you also take the popluar blood thinner called Coumadin (warfarin)? Grapefruit juice, when used to wash down certain atihistamines, immune suppressors, or blood pressure drugs, can cause blood levels of these powerful drugs to soar? The result: serious side effects. Birth control pills might be rendered ineffective by the following substances: barbituates, antibiotics, anti-fungal drugs, tuberculosis drugs, certain anticonvulsants? Is Your Life In Danger? Everyone has taken more than one pill simultaneously. Yet every time you combine drugs with prescription medicines, foods, vitamins, minerals, herbs or alcohol you explose yourself to the risk of a potentially dangerous interaction. Deadly Drug Interactions Can Help You. Over 200 easy-to-understand charts with information on medications for pain relief, allergies, asthma, arthritis, heart problems, depression, diabetes, contraception, ulcers and much more. Descriptions of the symptoms of interactions. Specific concerns of women, children and older people. Vital information of Lanoxin, Cardizem, Prozac, Mevacor, Ortho-Novum, Tagamet, Coumadin, Dilatin, Cipro, Synthroid, Procardia, and scores of other commonly prescribed medicines.
This volume brings together the large body of recent research on metabolic drug interactions and their relevance in the treatment of diseases. The book focuses on human metabolic enzyme systems that have been shown in vitro to be predictive of drug interactions. Major sections present information on specific therapeutic classes of drugs as substrates, inhibitors, and inducers of metabolic enzymes. Other chapters discuss the clinical and pharmacoeconomic implications of metabolic drug interactions and the significance of in vitro metabolic studies in new drug development.