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ACRP Report 38: Understanding Airspace, Objects, and Their Effects on Airports provides a comprehensive description of the regulations, standards, evaluation criteria, and processes designed to protect the airspace surrounding airports. Aviation practitioners, local planning and zoning agencies, and developers all have a need to understand and apply the appropriate airspace design and evaluation criteria to ensure a safe operating environment for aircraft, to maintain airport operational flexibility and reliability, without unduly restricting desirable building development and attendant economic growth in the surrounding community.
Edition 48 for 2016. The app links to charts, aerial photos, embedded videos, every marina, email support group, all port authorities, the wind charts, every anchorage, worldwide harbors, the tides, engine troubleshooting, all the weather, local knowledge, every dive site, every seabird, every pelagic fish, how to catch fish, animated knots, tips, Cruisers Forum, suggested itineraries, the nav rules, the ocean currents, all safety information, USCG, outboard engines, vessel traffic services, the radio frequencies, videos, every dock, every fuel supply, food, restaurants & supermarkets, every lighthouse, repairs, marine parks, general knowledge, your safety & security, sightseeing, the dive sites, all necessary books, USCG accident reports, safety check, Facebook group, Pinterest, Instagram, the nightlife, Crewfinder, Tumblr, Scuttlebutt, Snapchat group, Tripadvisor, environmental issues, all warnings, Chatbot, Live cams, Livestream, Events, Regulations, Wikipedia, put up your photos & videos, email group, Cruisers Forum, BoatBuzz, Top 20 sailing blogs, Links to all Gov agencies, official alerts & warnings and more... +The app on your phone, tablet and computer ready for any situation. + Link to First Aid and Sea Survival. + Phone and email out of the app. + Your screen can become a full screen weather radar. + See the surrounding ships in real time on your screen with a link to AIS. + View updated charts using online chart viewer. + Before departure download and print current charts in booklet form. Topics in this Pilot include channel descriptions, piracy, safety, anchorages, cloud cover, local winds, humidity, temperatures, bridge and cable clearances, dangerous waves, currents, tide and water levels, prominent features, visibility, cyclones, storms, fog, precipitation, pilotage, towage, weather, ice conditions, wharf descriptions, dangers, routes, traffic separation schemes, small-craft facilities, and Federal regulations applicable to navigation. GENERAL INFORMATION This is a huge resource on the app with hundreds of useful links to Government, USCG, Wikipedia etc. Chapter 2. NAVIGATION REGULATIONS The complete online updated Code of Federal Regulations is linked in the app. Chapter 3. California, Oregon, and Washington Chapter 4. San Diego to Point Arguello, California Chapter 5. CHANNEL ISLANDS. This chapter describes the eight Channel Islands They include the four islands of the southern group-San Clemente, Santa Catalina, San Nicolas, and Santa Barbara; Chapter 6. Point Arguello to San Francisco Bay, California Chapter 7. San Francisco Bay, California. Chapter 8. San Francisco Bay to Point St. George, California. This chapter describes Bodega Bay, Tomales Bay, Noyo River and Anchorage, Shelter Cove, Humboldt Bay. Chapter 9. Chetco River to Columbia River, Oregon This chapter describes 200 miles of the Oregon coast from the mouth of the Chetco River to the mouth of the Columbia River. Chapter 10. Columbia River, Oregon and Washington This chapter describes the Columbia River from its mouth at the Pacific Ocean to the head of navigation above Richland, Chapter 11. Columbia River to Strait of Juan De Fuca, Washington This chapter describes the Pacific coast of the State of Washington from the Washington-Oregon border at the mouth of the Columbia River Chapter 12. Strait of Juan De Fuca and Georgia, Washington. This chapter includes the Strait of Juan de Fuca, Sequim Bay, Port Discovery, the San Juan Islands and its various passages and straits, Deception Pass, Fidalgo Island, Chapter 13. Puget Sound, Washington This chapter describes Puget Sound and its numerous inlets, bays, and passages, and the waters of Hood Canal, Chapter 14. HAWAII The Hawai'ian Islands an archipelago, consist of eight large islands, plus many islets, reefs, and shoals, strung out from SE to NW for 1,400 nautical miles in the north-central Pacific Ocean. Chapter 15. PACIFIC ISLANDS
In the fall of 2010, the Office of the U.S. Department of Energy's (DOE's) Secretary for Science asked for a National Research Council (NRC) committee to investigate the prospects for generating power using inertial confinement fusion (ICF) concepts, acknowledging that a key test of viability for this concept-ignition -could be demonstrated at the National Ignition Facility (NIF) at Lawrence Livermore National Laboratory (LLNL) in the relatively near term. The committee was asked to provide an unclassified report. However, DOE indicated that to fully assess this topic, the committee's deliberations would have to be informed by the results of some classified experiments and information, particularly in the area of ICF targets and nonproliferation. Thus, the Panel on the Assessment of Inertial Confinement Fusion Targets ("the panel") was assembled, composed of experts able to access the needed information. The panel was charged with advising the Committee on the Prospects for Inertial Confinement Fusion Energy Systems on these issues, both by internal discussion and by this unclassified report. A Panel on Fusion Target Physics ("the panel") will serve as a technical resource to the Committee on Inertial Confinement Energy Systems ("the Committee") and will prepare a report that describes the R&D challenges to providing suitable targets, on the basis of parameters established and provided to the Panel by the Committee. The Panel on Fusion Target Physics will prepare a report that will assess the current performance of fusion targets associated with various ICF concepts in order to understand: 1. The spectrum output; 2. The illumination geometry; 3. The high-gain geometry; and 4. The robustness of the target design. The panel addressed the potential impacts of the use and development of current concepts for Inertial Fusion Energy on the proliferation of nuclear weapons information and technology, as appropriate. The Panel examined technology options, but does not provide recommendations specific to any currently operating or proposed ICF facility.
The potential for using fusion energy to produce commercial electric power was first explored in the 1950s. Harnessing fusion energy offers the prospect of a nearly carbon-free energy source with a virtually unlimited supply of fuel. Unlike nuclear fission plants, appropriately designed fusion power plants would not produce the large amounts of high-level nuclear waste that requires long-term disposal. Due to these prospects, many nations have initiated research and development (R&D) programs aimed at developing fusion as an energy source. Two R&D approaches are being explored: magnetic fusion energy (MFE) and inertial fusion energy (IFE). An Assessment of the Prospects for Inertial Fusion Energy describes and assesses the current status of IFE research in the United States; compares the various technical approaches to IFE; and identifies the scientific and engineering challenges associated with developing inertial confinement fusion (ICF) in particular as an energy source. It also provides guidance on an R&D roadmap at the conceptual level for a national program focusing on the design and construction of an inertial fusion energy demonstration plant.
EXTRACTABLES AND LEACHABLES Learn to address the safety aspects of packaged drug products and medical devices Pharmaceutical drug products and medical devices are expected to be effective and safe to use. This includes minimizing patient, user or product exposure to impurities leached from these items when the drug product is administered or when the medical device is used. Clearly, patient or user exposure to leachables must not adversely impact their health and safety. Furthermore, these impurities must not adversely affect key quality attributes of the drug product or medical device, including its manufacturability, stability, efficacy, appearance, shelf-life and conformance to standards. Extractables and leachables are derived from the drug product’s packaging, manufacturing systems and/or delivery systems or from the medical device’s materials of construction. It is imperative to understand and quantify the release of extractables from these items, the accumulation of leachables in drug products and the release of leachables from medical devices. Once extractables and leachables have been discovered, identified and quantified, their effect on the key product or device quality attributes, including safety, must be systematically and scientifically established according to recognized, rigorous and relevant regulatory and compendial standards and industry-driven best practices. In Extractables and Leachables, the chemical compatibility (including safe use) of drugs (and their containers, delivery devices and manufacturing systems) and medical devices is examined at length, focusing particularly on how trace-level extractables and leachables affect the quality and safety of a medical product and how to assess the magnitude of the effect. This is accomplished by addressing the two critical activities required to develop, register and commercialize safe, effective and affordable clinical therapies; measuring extractables and leachables (chemical characterization) and assessing their impact (for example, toxicological safety risk assessment). Each of these activities is addressed in-depth, based on the existing and developing international regulations and guidelines, current published literature and the author’s extensive personal experience. Written by a key contributor to standards, guidelines, recommended practices and the scientific literature, the book provides “insider” insights beyond those gained by merely reading the relevant texts. Given that the rapidly evolving extractables and leachables landscape, this book provides the most current and crucial information on new and forthcoming regulations and best practices. Extractables and Leachables readers will also find: A thorough summary of regulatory and compendial guidelines and the steps required to meet them A detailed and in-depth review of essential scientific principles and recommended best practices for the design, implementation, interpretation and reporting of chemical characterization studies A practical resource for optimizing the development, registration, and commercialization of safe and effective medical products A helpful tool to maximize product development and successful regulatory outcomes Extractables and Leachables is the essential reference for pharmaceutical scientists, analytical chemists, regulatory affairs professionals, engineers, and toxicologists in areas such as product research and development, product registration and approval, regulatory affairs, analytical science, quality control, and manufacturing.
Cutting-edge cybersecurity solutions to defend against the most sophisticated attacksThis professional guide shows, step by step, how to design and deploy highly secure systems on time and within budget. The book offers comprehensive examples, objectives, and best practices and shows how to build and maintain powerful, cost-effective cybersecurity systems. Readers will learn to think strategically, identify the highest priority risks, and apply advanced countermeasures that address the entire attack space. Engineering Trustworthy Systems: Get Cybersecurity Design Right the First Time showcases 35 years of practical engineering experience from an expert whose persuasive vision has advanced national cybersecurity policy and practices.Readers of this book will be prepared to navigate the tumultuous and uncertain future of cyberspace and move the cybersecurity discipline forward by adopting timeless engineering principles, including: •Defining the fundamental nature and full breadth of the cybersecurity problem•Adopting an essential perspective that considers attacks, failures, and attacker mindsets •Developing and implementing risk-mitigating, systems-based solutions•Transforming sound cybersecurity principles into effective architecture and evaluation strategies that holistically address the entire complex attack space