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Aims to present state-of-the-art studies in the application of forecasting methodologies to such areas as sales, marketing, and strategic decision making. The topics in this title include: sales and marketing, forecasting, new product forecasting, judgmentally based forecasting, the application of surveys to forecasting, and more.
Volume 4 of Advances in Medicinal Chemistry is comprised of six chapters on a wide range of topics in medicinal chemistry, including molecular modeling, structure-based drug design, organic synthesis, peptide conformational analysis, biological assessment, structure-activity correlation, and lead optimization. Chapter 1 presents an account about amino acid-based peptide mimetics corresponding to b-turn, loop, helical motifs in proteins as a probe of ligand-receptor and ligand-enzyme molecular interactions. Chapter 2 addresses new facets of the medicinal chemistry of the important anticancer drug Taxol® (paclitaxel). Chapter 3 relates an account of the search for new drugs for the treatment of malaria based on the natural product artemisinin. Chapter 4 applies computational chemistry to the evaluation of compound libraries for biological testing. Chapter 5 describes the construction of a 3-dimensional molecular model of the human thrombin receptor, the first protease-activated G-protein coupled receptor (PAR-1), as a means to explore the intermolecular contacts involved in agonist peptide recognition. Finally, Chapter 6 describes the research conducted at Merck on inhibitors of farnesyl transferase as a potential treatment for human cancers.
Advances in Nanoporous Materials is a collection of comprehensive reviews of lasting value to the field. The contributions cover all aspects of nanoporous materials, including their preparation and structure, post-synthetic modification, characterization and use in catalysis, adsorption/separation, and all other fields of potential application, e.g., membranes, host/guest chemistry, environmental protection, electrochemistry, sensors, and optical devices. "Nanoporous materials" comprise all kinds of porous solids that possess pores in the range from about 0.2 nm up to 50 nm, irrespective of their chemical composition, their origin (natural or synthetic), and their amorphous or crystalline nature. Typical examples are zeolites and zeolite-like materials (e.g., crystalline microporous aluminophosphates and their derivatives), mesoporous oxides such as silica, metal organic frameworks, pillared clays, porous carbons, and related materials. State-of-the-art reviews keep coverage current Broad scope provides a full topical overview Contributions from renowned experts lend authority to the material
Volume 4 of Advances in Developmental Biology and Biochemistry consists of five chapters that review specific aspects of fly and mammalian development. In Chapter 1, Y. Mishina and R. Behringer discuss various aspects of Müllerian-inhibiting substance (MIS) in mammals, from a brief history of its discovery to recent studies of the MIS gene in transgenic and knock-out animals. In Chapter 2, C. Rushlow and S. Roth discuss the role of the dpp-group genes in dorsoventral patterning of the Drosophila embryo. In Chapter 3, M. Yip and H. Lipshitz discuss the terminal (asegmental termini) gene hierarchy of Drosophila and the genetic control of tissue specification and morphogenesis. In Chapter 4, R. Bachvarova discusses induction of mesoderm and the origin of anterior-posterior polarity in the mouse embryo, using the frog embryo as a paradigm. In Chapter 5, P. Vogt discusses human Y chromosome function in male germ cell development.
"Multiphase flow and heat transfer have found a wide range of applications in several engineering and science fields such as mechanical engineering, chemical and petrochemical engineering, nuclear engineering, energy engineering, material engineering, ocea"
The present volume continues the trend established in previous volumes in this series on Advances in Structural Biology. As in the past, diverse topics of current importance relevant to the theme of the series are included in the fourth volume.
Advances in Porous Media, Volume 3 presents in-depth review papers that give a comprehensive coverage of the field of transport in porous media. This is the third volume in the series which treats transport phenomena in porous media as an interdisciplinary topic. The objective of each chapter is to review the work done on a specific topic including theoretical, numerical as well as experimental studies. All contributors are from a variety of backgrounds, such as civil and environmental engineering, earth and environmental sciences. The articles are aimed at scientists and engineers from various fields who are concerned with the fundamentals and applications of processes in porous media. Advances in Porous Media, Volume 3 is a valuable source of information for both researchers in the field and those working in other related disciplines.
Advances in Electronics and Electron Physics