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Celebrating 100 years of HEP, this volume will discuss key pharmacological discoveries and concepts of the past 100 years. These discoveries have dramatically changed the medical treatment paradigms of many diseases and these concepts have and will continue to shape discovery of new medicinies. Newly evolving technologies will similarly be discussed as they will shape the future of the pharmacology and, accordingly, medical therapy.
This book provides essential insights into microbial pathogenesis, host-pathogen interactions, and the anti-microbial drug resistance of various human pathogens on the basis of various model organisms. The initial sections of the book introduce readers to the mechanisms of microbial pathogenesis, host-pathogen interactions, anti-microbial drug resistance, and the dynamics of biofilm formation. Due to the emergence of various microbial resistant strains, it is especially important to understand the prognosis for microbial infections, disease progression profiles, and mechanisms of resistance to antibiotic therapy in order to develop novel therapeutic strategies. In turn, the second part of the book presents a comparative analysis of various animal models to help readers understand microbial pathogenesis, host-pathogen interactions, anti-microbial drug discovery, anti-biofilm therapeutics, and treatment regimes. Given its scope, the book represents a valuable asset for microbiologists, biotechnologists, medical professionals, drug development researchers, and pharmacologists alike.
This edited volume on machine learning and big data analytics (Proceedings of ICMLBDA 2021) is intended to be used as a reference book for researchers and practitioners in the disciplines of computer science, electronics and telecommunication, information science, and electrical engineering. Machine learning and Big data analytics represent a key ingredients in the industrial applications for new products and services. Big data analytics applies machine learning for predictions by examining large and varied data sets—i.e., big data—to uncover hidden patterns, unknown correlations, market trends, customer preferences, and other useful information that can help organizations make more informed business decisions.
This book constitutes revised papers from the nine workshops and one accompanying event which took place at the 22nd International Conference on Business Information Systems, BIS 2019, held in Seville, Spain, in June 2019. There was a total of 139 submissions to all workshops of which 57 papers were accepted for publication. The workshops included in this volume are: AKTB 2019: 11th Workshop on Applications of Knowledge-Based Technologies in Business BITA 2019: 10th Workshop on Business and IT Alignment BSCT 2019: Second Workshop on Blockchain and Smart Contract Technologies DigEX 2019: First International Workshop on transforming the Digital Customer Experience iCRM 2019: 4th International Workshop on Intelligent Data Analysis in Integrated Social CRM iDEATE 2019: 4th Workshop on Big Data and Business Analytics Ecosystems ISMAD 2019: Workshop on Information Systems and Applications in Maritime Domain QOD 2019: Second Workshop on Quality of Open Data SciBOWater 2019: Second Workshop on Scientific Challenges and Business Opportunities in Water Management
This clinically and practice oriented, multidisciplinary book is intended to fill the gap between evidence-based knowledge on the benefits of physical activity and exercise during pregnancy and the implementation of exercise programmes and related health promotion measures in pregnant women. It will provide medical, sports, and fitness professionals both with the knowledge needed to allay undue fears regarding the consequences of exercising during pregnancy and with the practical expertise to offer optimal guidance on exercising to pregnant exercisers and athletes. Readers will find up-to-date evidence on the psychological, social, physiological, body composition, musculoskeletal, and biomechanical changes that occur during pregnancy and their implications for physical activity and exercise. Detailed descriptions are provided of the components of exercise testing and prescription for pregnant women, the current evidence-based and practice-oriented guidelines, and exercise selection and adaptation during pregnancy. Exercises specifically targeting musculoskeletal health are discussed separately, and a concluding chapter explains the nutritional requirements in pregnant women who exercise.
The chapters of Studies on Periodontal Disease comprise four parts. Part 1 provides basic sciences from the general to the particular. The findings of cell culture and animal models supply the mechanism between periodontal disease and oxidative stress. In part 2, human clinical studies are mainly addressed. The effects of periodontal therapy on circulating oxidative stress are also discussed. The relationships between periodontal disease and systemic diseases are examined in part 3. The involvement of oxidative stress and inflammation are discussed through in vivo and in vitro study results. Part 4 discusses future strategies, including the effects of antioxidants and nutrition on periodontal disease. This thorough examination of the relationship between oxidative stress and periodontal disease is essential reading for researchers in oxidative stress and periodontal clinicians, alike.
This text contains an integrated bound-in CD-ROM, and has a strong emphasis on design. Its active visual approach and inclusion of space-orientated engineering make it an interesting examination of the aerospace engineering field.
This manual takes a multidisciplinary approach to neurological disorders in the elderly. Comprehensive and practical, it includes the most recent diagnostic criteria and immediately accessible visual care paths including the latest pharmacologic and non-pharmacologic interventions. Covering a range of modalities, from the importance and impact of each disease to diagnostic criteria, genetics, laboratory and imaging findings, treatment and care paths, this book focuses on neurological conditions that occur commonly in older persons or which have a striking effect on their lives. The common types of dementias, Parkinson’s disease and related disorders, rapidly progressive diseases, seizure disorders and multiple sclerosis are covered. Issues commonly affecting this population, such as neurobehavioral symptoms and caregiver issues, are discussed. Neuro-Geriatrics: A Clinical Manual is aimed at any physician who treats the elderly with neurological disorders: neurologists, geriatricians and geriatric psychiatrists, both specialists and general practitioners.