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Discover your true life calling in a world of endless possibilities with Pascal Bachmann's step-by-step guide to finding your highest point of contribution. Learn to navigate your unique intersection of talents and passions, and transform them into profitable business opportunities.
Does your heart desire to discover your life’s purpose and live a life that is filled with love, joy and abundance? You can be, do, and have everything your heart desires for you by creating your life’s work, believing in your higher self and taking inspired action. If you are ready to let go of everything that no longer serves your higher purpose, breaking free from limiting beliefs, shifting challenges into opportunities, and choosing a life that is filled with passion, purpose, and prosperity. You will enjoy the journey of awakening your spiritual abundance with the help of the Archangels. This step-by-step 5Ps to Prosperity Process will be the secret ingredients for Being, Doing and Having everything your heart desires.
Life is not what you get out of it . . . it’s what you put back in. Yet our current means for summarizing life’s work, from resumes to salaries, are devoid of what matters most. This is why the work we do is often bad for our wellbeing, when it should be making us happier and healthier. What are the most meaningful contributions we can make? This is Life’s Great Question. Life is about what you do that improves the world around you. It is about investing in the development of other people. And it is about efforts that will continue to grow when you are gone. Life’s Great Question will show you how to make your work and life more meaningful, and greatly boost your wellbeing. In this remarkably quick read, author Tom Rath describes how finding your greatest contribution is far more effective than following talent or passion alone. More than a book, each copy includes a code for an online program that identifies the most significant contributions you can make. This deeply practical book will alter how you look at your work and change the way you live each day.
Have you ever considered that you may have created your present reality? Could you have been attracting people and situations in your life unconsciously and creating the circumstances you are experiencing? If so, can you make this process conscious and restructure your life as you wish? If you are truly manifesting your reality, should you not attempt to create an energizing and joyful existence, living your life to its highest potential? This book will create a paradigm shift in your understanding of reality by questioning your deepest assumptions and then take you step by step through a practical, easy to implement process to create the life you desire. It will set you on an exciting path of self-discovery and reclaiming control no matter what stage of life you are at.
Chemoinformatics strategies to improve drug discovery results With contributions from leading researchers in academia and the pharmaceutical industry as well as experts from the software industry, this book explains how chemoinformatics enhances drug discovery and pharmaceutical research efforts, describing what works and what doesn't. Strong emphasis is put on tested and proven practical applications, with plenty of case studies detailing the development and implementation of chemoinformatics methods to support successful drug discovery efforts. Many of these case studies depict groundbreaking collaborations between academia and the pharmaceutical industry. Chemoinformatics for Drug Discovery is logically organized, offering readers a solid base in methods and models and advancing to drug discovery applications and the design of chemoinformatics infrastructures. The book features 15 chapters, including: What are our models really telling us? A practical tutorial on avoiding common mistakes when building predictive models Exploration of structure-activity relationships and transfer of key elements in lead optimization Collaborations between academia and pharma Applications of chemoinformatics in pharmaceutical research experiences at large international pharmaceutical companies Lessons learned from 30 years of developing successful integrated chemoinformatic systems Throughout the book, the authors present chemoinformatics strategies and methods that have been proven to work in pharmaceutical research, offering insights culled from their own investigations. Each chapter is extensively referenced with citations to original research reports and reviews. Integrating chemistry, computer science, and drug discovery, Chemoinformatics for Drug Discovery encapsulates the field as it stands today and opens the door to further advances.
THE LIFE-CHANGING NEW YORK TIMES BESTSELLER • MORE THAN TWO MILLION COPIES SOLD • Now in a 10th anniversary edition featuring a new introduction and bonus 21-day challenge. “Essentialism holds the keys to solving one of the great puzzles of life: How can we do less but accomplish more?”—Adam Grant, bestselling author of Think Again Essentialism isn’t about getting more done in less time. It’s about getting only the right things done. Have you ever found yourself stretched too thin? Are you often busy but not productive? Do you feel like your time is constantly being hijacked? If you answered yes to any of these, the way out is the Way of the Essentialist. Essentialism is more than a time-management technique. It is a systematic discipline for discerning what is absolutely essential, then eliminating everything that is not, so we can make the highest possible contribution toward the things that really matter. By forcing us to apply more selective criteria for where to spend our precious time and energy, the disciplined pursuit of less empowers us to reclaim control of our own choices, instead of giving others the implicit permission to choose for us. Essentialism is not one more thing to do. It’s a whole new way of doing less, but better, in every area of our lives. Join the millions of people who have used Essentialism to change their outlook on the world.
Legendary leaders change the world by putting leadership at the service of humanity Humanise is a comprehensive look at human-centred leadership, providing insight and guidance for those who want to change the world. A deep examination of the concept of moral leadership, this book examines what it is, how it's acquired, and how it can be applied in business, government, and society. Readers will gain insight into predominant leadership styles exemplified in governments and organizations around the world, and discover the missing pieces that come together to more effectively guide people through challenges and transitions. With a focus on building a solid foundation, a strong moral compass, and deep empathy for others, this book shows you how to be a leader wherever you are, build your leadership capability, and make a positive impact on the world. We are facing a crisis of leadership. Where are the new Mandelas? What type of person is that? What are their qualities and attributes? Who will lead us into the future? Humanise is a book for people who want to be the very best version of themselves, the best leader they can be, and impact the world for good. Discover a different perspective on the leadership crisis throughout the world Create your own leadership foundation starting with your purpose and principles Turn your personal moral values into a leadership style that will benefit and inspire others Influence the individuals and world around you to become a part of the solution Following in the footsteps of Mandela and Ghandi, this book explains why great leadership is human-centred, and how you can become such a leader, no matter who you are or what position you are in. For those interested in picking up the torch and guiding the way, Humanise provides a roadmap to the version of you you've always wanted to be, and that the world needs you to be.
Ever since Newton created dynamics, there has been controversy about its foundations. Are space and time absolute? Do they form a rigid but invisible framework and container of the universe? Or are space, time, and motion relative? If so, does Newton's 'framework' arise through the influence of the universe at large, as Ernst Mach suggested? Einstein's aim when creating his general theory of relativity was to demonstrate this and thereby implement 'Mach's Principle'. However, it is widely believed that he achieved only partial success. This question of whether motion is absolute or relative has been a central issues in philosophy; the nature of time has perennial interest. Current attempts to create a quantum description of the whole universe keep these issues at the cutting edge of modern research. Written by the world's leading expert on Mach's Principle, The Discovery of Dynamics is a highly original account of the development of notions about space, time, and motion. Widely praised in its hardback version, it is one of the fullest and most readable accounts of the astronomical studies that culminated in Kepler's laws of planetary motion and of the creation of dynamics by Galileo, Descartes, Huygens, and Newton. Originally published as Absolute or Relative Motion?, Vol. 1: The Discovery of Dynamics (Cambridge), The Discovery of Dynamics provides the technical background to Barbour's recently published The End of Time, in which he argues that time disappears from the description of the quantum universe.
The top quark is by far the heaviest known fundamental particle with a mass nearing that of a gold atom. Because of this strikingly high mass, the top quark has several unique properties and might play an important role in electroweak symmetry breaking—the mechanism that gives all elementary particles mass. Creating top quarks requires access to very high energy collisions, and at present only the Tevatron collider at Fermilab is capable of reaching these energies. Until now, top quarks have only been observed produced in pairs via the strong interaction. At hadron colliders, it should also be possible to produce single top quarks via the electroweak interaction. Studies of single top quark production provide opportunities to measure the top quark spin, how top quarks mix with other quarks, and to look for new physics beyond the standard model. Because of these interesting properties, scientists have been looking for single top quarks for more than 15 years. This thesis presents the first discovery of single top quark production. It documents one of the flagship measurements of the D0 experiment, a collaboration of more than 600 physicists from around the world. It describes first observation of a physical process known as “single top quark production”, which had been sought for more than 10 years before its eventual discovery in 2009. Further, his thesis describes, in detail, the innovative approach Dr. Gillberg took to this analysis. Through the use of Boosted Decision Trees, a machine-learning technique, he observed the tiny single top signal within an otherwise overwhelming background. This Doctoral Thesis has been accepted by Simon Fraser University, Burnaby, BC, Canada.
Rocket scientist, internet entrepreneur, and popular speaker Mary Spio presents practical advice for beating the odds, breaking the mold, and charting your own path to achieve true success Mary Spio went from being a barefoot girl in Ghana to a rocket scientist with major patents with Boeing. Mary is also an internet entrepreneur who speaks throughout the world about how anyone with a dream and some tools can harness the digital world for success and prosperity. In IT'S NOT ROCKET SCIENCE, she presents advice and empowering stories that will inspire readers to move beyond their comfort zones into mastery and empowerment. IT'S NOT ROCKET SCIENCE reveals the habits and traits of people who defy convention, overcome limited thinking, and crush the odds to achieve breakthrough success—and shows readers how to strike their own uncommon path. It shares the secrets to cultivating curiosity, creativity, compassion, audacity, passion, obsessive focus and tenacity to attain their dreams and change the world. It's not Rocket Science is an inspiring and entertaining read for anyone who desires to be empowered with the mindset needed to propel their life to new heights. • Learn how some of the world’s most successful people shatter boundaries. • Discover how your difference creates your relevance and your significance. • Uncover your inner spark and learn how to fuel your own flame. • Understand why a Defy-ing Moment is a defining moment. • Find your path to success –however you define it.