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Fungal dimorphism is a topic that sounds inherently too rarified to attract more than a specialist audience. Yet some 230 individuals representing an eclectic mixture of interests, from basic science to medical practice, gathered in Churchill College, Cambridge in Semptember 1992 for a meeting devoted only to this subject. The symposium was the fourth in a series "Topics in Mycology" to be jointly organized by the Janssen Research Foundation and the International Society for Human and Animal Mycology. The participants enjoyed a rich and varied diet of oral presentations and poster displays in the field of fungal morphogenesis. This book sets down in print the material presented at the dimorphism symposium. We think that the high quality of these papers conveys very well the flavor of what was an excellent meeting. The selection of contributions in this volume covers very wide ground indeed. Chapters devoted to some non-pathogenic fungi are included, because the scientific basis of morphological development belongs to the fields of cellular and molecular biology: it does not recognize the boundary imposed by considerations of virulence of a fungus for a human host. Yet morphogenetic change in those fungi that do cause human disease frequently appears to be a component of the pathological process: many important pathogens change from a hyphal form in the external environment to a round form in infected tissues. This relationship between dimorphism and pathogenicity is the point of contact between pure biology and medicine.
The Oxford Textbook of Medical Mycology is a comprehensive reference text which brings together the science and medicine of human fungal disease. Written by a leading group of international authors to bring a global expertise, it is divided into sections that deal with the principles of mycology, the organisms, a systems based approach to management, fungal disease in specific patient groups, diagnosis, and treatment. The detailed clinical chapters take account of recent international guidelines on the management of fungal disease. With chapters covering recent developments in taxonomy, fungal genetics and other 'omics', epidemiology, pathogenesis, and immunology, this textbook is well suited to aid both scientists and clinicians. The extensive illustrations, tables, and in-depth coverage of topics, including discussion of the non-infective aspects of allergic and toxin mediated fungal disease, are designed to aid the understanding of mechanisms and pathology, and extend the usual approach to fungal disease. This textbook is essential reading for microbiologists, research scientists, infectious diseases clinicians, respiratory physicians, and those managing immunocompromised patients. Part of the Oxford Textbook in Infectious Disease and Microbiology series, it is also a useful companion text for students and trainees looking to supplement mycology courses and microbiology training.
Fungi: Biology and Applications, Second Edition provides a comprehensive treatment of fungi, covering biochemistry, genetics and the medical and economic significance of these organisms at introductory level. With no prior knowledge of the subject assumed, the opening chapters offer a broad overview of the basics of fungal biology, in particular the physiology and genetics of fungi and also a new chapter on the application of genomics to fungi. Later chapters move on to include more detailed coverage of topics such as antibiotic and chemical commodities from fungi, new chapters on biotechnological use of fungal enzymes and fungal proteomics, and fungal diseases of humans, antifungal agents for use in human therapy and fungal pathogens of plants.
Descriptions of Medical Fungi. Third Edition. Sarah Kidd, Catriona Halliday, Helen Alexiou and David Ellis. 2016. This updated third edition which includes new and revised descriptions. We have endeavoured to reconcile current morphological descriptions with more recent genetic data. More than 165 fungus species are described, including members of the Zygomycota, Hyphomycetes, Dimorphic Pathogens, Yeasts and Dermatophytes. 340 colour photographs. Antifungal Susceptibility Profiles. Microscopy Stains & Techniques. Specialised Culture Media. References. 250 pages.
Fungal dimorphism is a topic that sounds inherently too rarified to attract more than a specialist audience. Yet some 230 individuals representing an eclectic mixture of interests, from basic science to medical practice, gathered in Churchill College, Cambridge in Semptember 1992 for a meeting devoted only to this subject. The symposium was the fourth in a series "Topics in Mycology" to be jointly organized by the Janssen Research Foundation and the International Society for Human and Animal Mycology. The participants enjoyed a rich and varied diet of oral presentations and poster displays in the field of fungal morphogenesis. This book sets down in print the material presented at the dimorphism symposium. We think that the high quality of these papers conveys very well the flavor of what was an excellent meeting. The selection of contributions in this volume covers very wide ground indeed. Chapters devoted to some non-pathogenic fungi are included, because the scientific basis of morphological development belongs to the fields of cellular and molecular biology: it does not recognize the boundary imposed by considerations of virulence of a fungus for a human host. Yet morphogenetic change in those fungi that do cause human disease frequently appears to be a component of the pathological process: many important pathogens change from a hyphal form in the external environment to a round form in infected tissues. This relationship between dimorphism and pathogenicity is the point of contact between pure biology and medicine.
Fungi research and knowledge grew rapidly following recent advances in genetics and genomics. This book synthesizes new knowledge with existing information to stimulate new scientific questions and propel fungal scientists on to the next stages of research. This book is a comprehensive guide on fungi, environmental sensing, genetics, genomics, interactions with microbes, plants, insects, and humans, technological applications, and natural product development.
The first book of its kind to focus on the diagnosis, prevention, and treatment of patients with fungal infections, this definitive reference returns in a completely revised, full-color new edition. It presents specific recommendations for understanding, controlling, and preventing fungal infections based upon underlying principles of epidemiology and infection control policy, pathogenesis, immunology, histopathology, and laboratory diagnosis and antifungal therapy. More than 560 photographs, illustrations, and tables depict conditions as they appear in real life and equip you to identify clinical manifestations with accuracy. Expanded therapy content helps you implement the most appropriate treatment quickly, and a bonus CD-ROM-featuring all of the images from the text-enables you to enhance your electronic presentations. Includes specific recommendations for diagnosing, preventing, and treating fungal infections in various patient populations based upon underlying principles of epidemiology and infection control policy, pathogenesis, immunology, histopathology, and laboratory diagnosis and antifungal therapy. Covers etiologic agents of disease, fungal infections in special hosts such as pediatric patients and patients with cancer and HIV, infections of specific organ systems, and more, to make you aware of the special considerations involved in certain cases. Features clinically useful and reader-friendly practical tools-including algorithms, slides, graphs, pictorials, photographs, and radiographs-that better illustrate and communicate essential points, promote efficient use in a variety of clinical and academic settings, and facilitate slide making for lectures and presentations. Offers a CD-ROM containing all of the book's images for use in your electronic presentations. Offers more clinically relevant images-more than 300 in full color for the first time-to facilitate diagnosis. Features expanded therapy-related content, including up-to-date treatment strategies and drug selection and dosing guidelines. Includes several new sections in the chapter on fungal infections in cancer patients that reflect the formidable clinical challenges these infections continue to present. Presents the work of additional international contributors who have defined many of the key issues in the field, providing more of a global perspective on the best diagnostic and management approaches. Uses a new, full-color design to enhance readability and ease of access to information.
Black & white print. Concepts of Biology is designed for the typical introductory biology course for nonmajors, covering standard scope and sequence requirements. The text includes interesting applications and conveys the major themes of biology, with content that is meaningful and easy to understand. The book is designed to demonstrate biology concepts and to promote scientific literacy.
Fungal diseases have contributed to death and disability in humans, triggered global wildlife extinctions and population declines, devastated agricultural crops, and altered forest ecosystem dynamics. Despite the extensive influence of fungi on health and economic well-being, the threats posed by emerging fungal pathogens to life on Earth are often underappreciated and poorly understood. On December 14 and 15, 2010, the IOM's Forum on Microbial Threats hosted a public workshop to explore the scientific and policy dimensions associated with the causes and consequences of emerging fungal diseases.
The identification of medically important fungi has been an important area of study that warrants further extensive research. The use oftraditional and molecular methods of identification, provides new insights into differentiation of species and ultimately the line of treatment can be determined. This book incorporates a diverse group of medically